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Sigma-Aldrich Announces New Prestige Antibodies(TM) Line for Proteomics and Cell Biology Researchers
Date:2/14/2008

Sigma-Aldrich and Atlas Antibodies Establish Exclusive Distribution

Partnership

ST. LOUIS, Feb. 14 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) today announced an exclusive partnership with Atlas Antibodies to distribute Prestige Antibodies(TM) -- developed by the Human Proteome Resource -- to the proteomics and cell biology research communities. Initially consisting of 1800 antibodies, the library is expected to grow by several thousand per year with the goal of producing at least one antibody to all 22,000 non-redundant human proteins by 2015. Through this partnership, Sigma-Aldrich is granted exclusive distribution rights in the U.S. and all regions outside of Europe, with co-exclusive distribution rights in Europe.

Prestige Antibodies(TM) are highly characterized and offer significant value to the research community. Each antibody is highly validated for specificity and accompanied by over 500 immunohistochemical images, which are displayed in the publicly accessible Human Protein Atlas. In addition, Prestige Antibodies(TM) are optimized on a single protocol and tailored for high throughput operations, providing significant time and cost savings for researchers. The antibodies are designed to have low cross-reactivity to other human proteins and to work in a variety of applications and tissue preparations. All Prestige Antibodies(TM) are tested in multiple assurance steps to ensure that they are the most specific products on the market.

"We are delighted to have been chosen as the exclusive distributor of Prestige Antibodies(TM), and we expect to release substantial additions to the catalog annually," said Dr. David Smoller, President of Sigma-Aldrich's Research Biotech business unit. "By making these high quality and highly validated antibodies accessible to proteomics and cell biology researchers worldwide, Sigma-Aldrich is helping to further promote the study of disease."

Atlas Antibodies is a biotech company established in 2006 to produce the antibodies identified by the Human Proteome Resource (HPR), a major component of the Human Proteome Organization (HUPO) that is systematically exploring the human proteome using antibody-based proteomics. As the library developed by Atlas Antibodies grows each year, Sigma-Aldrich will expand its catalog of Prestige Antibodies(TM).

"Sigma-Aldrich offers a recognized brand name and an established distribution network that will help us bring our antibodies to market", said Marianne Hansson, co-founder and CEO of Atlas Antibodies. "This partnership will enable Atlas Antibodies to reach all of the proteomics and cell biology researchers who will benefit from the unprecedented specification of the Prestige Antibodies(TM)."

Prestige Antibodies(TM) are available at http://www.sigma.com/prestige, where customers can search for available antibodies by specific gene name and ID, or by browsing individual chromosomes.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 36 countries and has 7,900 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at http://www.sigma-aldrich.com.

About Atlas Antibodies: Atlas Antibodies was founded in 2006 by researchers at the Royal Institute of Technology (KTH) in Stockholm and the Rudbeck Laboratory, Uppsala University in Uppsala, Sweden. Atlas Antibodies will handle the production, marketing and sales of the antibody products developed and validated in the Human Proteome Resource (HPR) Center. The Human Proteome Resource (HPR) Center is performing a systematic exploration of the human proteome with Affinity (Antibody) based Proteomics, combining high-throughput generation of affinity-purified (mono-specific) antibodies with protein profiling using tissue microarrays. The Human Proteome Resource (HPR) Center is located in Stockholm and Uppsala, Sweden and is running the Swedish Human Protein Atlas (HPA) program. The HPA program generates expression and localization patterns of proteins in a large portion of both normal and cancer human tissues and organs resulting in the antibody-based profiling presented in the publicly available Human Protein Atlas (HPA) (http://www.proteinatlas.org). The HPA vision is to enable the systematic generation of quality assured antibodies to all non-redundant human proteins and to use these reagents to functionally explore human proteins, protein variants and protein interactions.

Cautionary Statement: This release contains forward-looking statements relating to future performance, goals, strategic actions and initiatives and similar intentions and beliefs and other statements regarding the Companies' expectations, goals, beliefs, intentions and the like, which involve assumptions regarding the Companies' operations and conditions in the markets the Companies serve. The Companies do not undertake any obligation to update these forward-looking statements.


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