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Sigma-Aldrich Announces Collaboration With Metahelix Life Sciences
Date:7/8/2008

Partnership to provide expertise and applications support in plant

biotechnology

ST. LOUIS, July 8 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) and Metahelix Life Sciences today announced a partnership under which Metahelix will assist in developing applications data for Sigma-Aldrich's plant bioscience product line, and provide expert technological guidance regarding usage. The efforts of this collaboration will occur in Metahelix's existing facility, located adjacent to Sigma-Aldrich's manufacturing and distribution center in Bangalore, India, and provide support for Sigma-Aldrich customers throughout the Pacific Rim and Latin America.

"The plant biotechnology market is growing rapidly in Latin America and Asia as biofuels and the rapid expansion of urban centers drives increased demand for higher productivity crops," said Susan Riley, director of international business at Sigma-Aldrich. "This partnership with Metahelix is expected to enable us to support our customers with practical guidance by a firm that works with a number of different species of plants."

Guatham Nadig, head of research and development at Metahelix, said: "Metahelix will benefit from visibility of new tools available to develop our commercial offerings in the plant bioscience area."

Sigma-Aldrich serves the plant biotechnology research market with a variety of genomic and proteomic solutions, including whole genome amplification and RNA purification kits (http://www.sigmaaldrich.com/plant). The Company's leading Extract-N-Amp(TM) plant PCR technology dramatically reduces the amount of time required to extract and amplify genomic DNA from plant tissue, facilitating rapid screening. Sigma-Aldrich's SpyLine(TM) plant mRNA capture kits allow for the isolation of mRNA and performance of RT-PCR in a single 96-well PCR plate incorporating Oligo (dT) primers, eliminating transfer steps and increasing throughput. Unique to the market, the Company's Spectrum(TM) Plant Total RNA Kits succeed where most protocols fail, employing patent-pending lysis and binding chemistry to purify total RNA from plant tissues that contain high levels of secondary metabolites.

To learn more about Sigma-Aldrich's extensive offering of products and kits for the plant bioscience research community, visit http://www.sigmaaldrich.com/plant.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 36 countries and has 7,900 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at http://www.sigma-aldrich.com.

About Metahelix: Metahelix is an agricultural biotechnology company focusing on developing traits and technologies for crop protection & improved productivity. Hybrid Seeds and traits are commercialized by its wholly owned subsidiary seeds business Dhaanya Seeds. Metahelix also provides customized research to select global Ag-biotech business using its proprietary technologies in crop transformation and functional genomics. Metahelix is based at Bangalore India, which is home to a growing number of new-age high technology ventures. For more information about Metahelix, visit http://www.meta-helix.com/.

Cautionary Statement: This release contains forward-looking statements relating to future performance, goals, strategic actions and initiatives and similar intentions and beliefs and other statements regarding the Companies' expectations, goals, beliefs, intentions and the like, which involve assumptions regarding the Companies' operations and conditions in the markets the Companies serve. The Companies do not undertake any obligation to update these forward-looking statements.

Sigma-Aldrich, Spectrum, SpyLine and Extract-N-Amp are trademarks of Sigma-Aldrich Biotechnology L.P. and Sigma-Aldrich Co.


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