Sigma-Aldrich(R) and Sangamo BioSciences Announce Major Expansion of ZFP Technology License... (nphier Sangamo's President and CEO. Sig...)

Sigma-Aldrich(R) and Sangamo BioSciences Announce Major Expansion of ZFP Technology License Agreement

Date:10/5/2009

nphier, Sangamo's President and CEO. "Sigma-Aldrich has been aggressively developing, marketing and distributing ZFP-based products through their CompoZr website, and we anticipate the same success in these expanded markets of cell line engineering and transgenic animal products. Sangamo's business model enables us to access non-dilutive funding for our core ZFP Therapeutic(TM) programs by monetizing the industrial applications of our ZFP technology with a focused and committed partner. Sigma-Aldrich has proven to be just that."

For more information on Sigma-Aldrich's CompoZr ZFN technology platform, visit http://www.compozrzfn.com or contact a sales representative at zfn@sial.com.

Terms of the License Agreement Amendment

The expanded agreement provides Sigma-Aldrich with exclusive rights to develop and distribute ZFP-modified cell lines for commercial production of protein pharmaceuticals and ZFP-engineered transgenic animals for livestock, companion animals and therapeutic protein production. Sangamo retained all rights to ZFP-modified transgenic animals for discovery of novel therapeutics and the right to use ZFPs as therapeutic products. Under this agreement, Sigma-Aldrich will make initial payments of $20.0 million to Sangamo, consisting of an upfront license payment of $15.0 million and $5.0 million through the purchase of 636,133 shares of Sangamo common stock at market price. Market price is determined by the average closing price of Sangamo stock over the past 30 trading days, or $7.86 per share. Sangamo is eligible to earn additional contingent commercial license fees of up to $5.0 million based on certain conditions and thereafter a royalty based upon a percentage of net sales and sublicensing revenue. Sangamo is also eligible to receive commercial milestone payments ranging from $2.0 million to $10.0 million, up to a tota
'/>"/>

SOURCE Sigma-Aldrich Corporation
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Post Your Comments:

(Date:12/15/2009)... N.Y., Dec. 15 On January 20th, ... Society for Medical Publication Professionals (ISMPP) will be ... London, UK. More than 100 attendees are expected ... for publication professionals, editors, publishers, medical writers and ... medical publications and the impact of guidelines and ...

(Date:12/15/2009)... of several innovative new programs to aid cash-strapped entrepreneurs ... climate. The first is aimed at entrepreneurs and ... a period of 6, 12, 18, or 24 months ... The second is aimed at more established businesses and ... 12 month period at discounted rates, and even the ...

(Date:12/14/2009)... Dec. 14 Dyadic International, Inc. (Pink ... extended its collaboration with The Scripps Research Institute ... to re-annotate the genome of Dyadic,s patented and ... a continuation of the successful relationship between the ... Dyadic engaged Scripps to annotate the C1 genome ...

(Date:12/14/2009)... 14 Boston Scientific Corporation (NYSE: ... offering of $2 billion aggregate principal amount of its ... The public offering consists of $850 million of 4.50 ... percent notes due January 2020 and $300 million of ... plans to use the net proceeds for general corporate ...

Breaking Biology Technology:Announcing ISMPP EU 2010 - the First European Meeting of the International Society for Medical Publication Professionals, Royal College of Physicians, London, UK, January 20, 2010 2 The Prinz Law Office Launches Innovative New Programs to Aid Cash-Strapped Entrepreneurs and Businesses 2 Dyadic International Extends Collaboration With The Scripps Research Institute 2 Dyadic International Extends Collaboration With The Scripps Research Institute 3 Dyadic International Extends Collaboration With The Scripps Research Institute 4 Dyadic International Extends Collaboration With The Scripps Research Institute 5 Boston Scientific Announces Completion of $2 Billion Senior Notes Offering 2 Boston Scientific Announces Completion of $2 Billion Senior Notes Offering 3

[0] Announcing ISMPP EU 2010 - the First European Meeting of the International Society for Medical Publication Professionals, Royal College of Physicians, London, UK, January 20, 2010 [0] The Prinz Law Office Launches Innovative New Programs to Aid Cash-Strapped Entrepreneurs and Businesses [0] Dyadic International Extends Collaboration With The Scripps Research Institute [0] Boston Scientific Announces Completion of $2 Billion Senior Notes Offering

... Key milestones, - Strong R&D investments, especially in EHT Dx21 and ... - Recruitment of 311 samples achieved for EHT Dx21, ... - Expansion of the strategic collaboration with Allergan and extension, ... Appointment of a new Management Board, - New positioning of Genomic ...

... March 3 NeoGenomics, Inc. (OTC Bulletin Board: ... its fourth quarter and full year 2008 financial results on ... conference call to discuss their Q4 and full year 2008 ... Interested investors should dial (877) 407-8033 (domestic) and (201) 689-8033 ...

... Leverage Respective Technology and Market Experience to Support ... Sparta Systems, Inc., the leading provider of ... the appointment of two software and life sciences ... Diane Carlson, vice president of marketing communications, and ...

ExonHit Therapeutics Invested Strongly in 2008 for Pivotal 2009 Results NeoGenomics Schedules its Q4 and Full Year 2008 Earnings Release for March 5, 2009 Sparta Systems Bolsters Executive Leadership Team with Strategic Additions

(Date:12/15/2009)... WI, December 15, 2009 Economics, environmental impacts, ... factors that influence the overall success of an ... on the system, forcing individuals and social groups ... order to survive. , Experiential learning theory ... result of firsthand experiences. Such lessons are especially ...

(Date:12/15/2009)... American researchers found the fossil remains of a whale, 4.5 ... for the first time, the results of the decay and ... cetacean, possibly a baleen whale from the Mysticeti group. , ... remains of a whale from the Lower Pliocene (five million ... is the first time that the results of the processes ...

(Date:12/15/2009)... HERNDON, Va., Dec. 15 The PTR Group, ... today announced that it has agreed to sponsor three ... US FIRST Robotics Competition ( http://usfirst.org ). ... high school teams in three different states. The ... in Rockwall, TX, and James Madison HS in Vienna, ...

Breaking Biology News(10 mins):Experiential learning teaches change and adaptation 2 Story of 4.5 million-year-old whale unveiled in Huelva 2 Story of 4.5 million-year-old whale unveiled in Huelva 3 The PTR Group Announces Financial and Technical Support to US FIRST Robotics Competition Teams 2 ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA 13440 1 ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA 13440 2 LCA Announces More Requests for Bids on Lung Cancer Research Programs Funded Through the Department of Defense 53923 1 LCA Announces More Requests for Bids on Lung Cancer Research Programs Funded Through the Department of Defense 53923 2 Matrixx Initiatives Inc Sets Time for Discussion of First Quarter Fiscal 2010 Financial Results 53918 1 Matrixx Initiatives Inc Sets Time for Discussion of First Quarter Fiscal 2010 Financial Results 53918 2

[0] Experiential learning teaches change and adaptation [0] Story of 4.5 million-year-old whale unveiled in Huelva [0] The PTR Group Announces Financial and Technical Support to US FIRST Robotics Competition Teams

... in the body, a virus such as HIV invades body ... membrane. Once inside the cell, the invading microbe's genetic material ... produce more copies of the virus, which then spill out ... assumed that once a virus begins fusing with a cell's ...

... in the impact of malaria is in prospect with a ... next year. Success in the trial would open the way ... debilitating and often fatal disease - over 500,000,000 people. ... is collaborating with the Papua New Guinea Institute of Medical ...

... San Francisco VA Medical Center (SFVAMC) and the University ... associated with lymphocytic bronchitis, which is thought to lead ... long-term failure of transplanted lungs. , The researchers hope ... and more accurate standard test for chronic lung rejection, ...

Other Biology News:Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development 2 Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development 3 Old drug, new tricks: Prospects for slashing the impact of malaria 2 Researchers identify genes associated with lung transplant rejection 2

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development Old drug, new tricks: Prospects for slashing the impact of malaria Researchers identify genes associated with lung transplant rejection

... Safe photographic filter (S37100, Photographic Filters ... is ideal for black-and-white photography of ... DNA gel stain, the safer ethidium ... Safe photographic filter is identical to ...

The Zymo-Spin PI Fast-Spin column features durable polypropylene construction and is the same column featured in the His-Spin Protein Miniprep. Capacity is 800 l....

Enodgenous alkaline phosphotase inhibitor. Levamisole solution is supplied in concentrated form (20x). The final concentration of levamisole in the substrate solution will be 1 mM....

LAL Chromogenic Endpoint assay...

Biology Products:

SYBR Safe photographic filter from Molecular Probes (Invitrogen)Zymo-Spin PI from Zymo Research LEVAMISOLE SOLUTION from Invitrogen bacterial endotoxin Chromogenic Assay Kit from Cell Sciences

Sigma-Aldrich(R) and Sangamo BioSciences Announce Major Expansion of ZFP Technology License...(nphier Sangamo's President and CEO. Sig...)