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Sigma-Aldrich (Nasdaq: SIAL) Reports Q4 and Full Year 2010 Diluted EPS of $0.76 and $3.12, Respectively. Q4 and Full Year 2010 Adjusted Diluted EPS Were $0.83 and $3.31, Respectively. Q4 Sales Set New Quarterly High. 2011 Diluted EPS Expected to be
Date:2/9/2011

organic growth in SAFC, and to enhance our e-commerce and Asia Pacific-Latin American market sales. All of these efforts are intended in an effort to once again boost sales growth above the underlying market rate.  

Excluding any special charges, we also expect to hold our operating profit margin close to the level achieved in 2010.  Our 2011 plans include continuing benefits from our sales growth and operations improvement initiatives. We plan to reinvest some of those benefits in the initiatives that are expected to accelerate sales growth rate in the future. In addition, we also plan to create our new European headquarters in Switzerland to more effectively manage our efforts in the important EMEA market. These additional expenses are included in our earnings outlook. Our diluted EPS, exclusive of any restructuring and other extraordinary special charges, should increase by 4% to 9% to a range of $3.45 to $3.60.  Let me assure you that our management team is fully engaged and committed to deliver this performance."

2010 RESULTS:Reported sales for the fourth quarter of 2010 of $582 million increased 2% from the fourth quarter of 2009.  Excluding a 1% impact from unfavorable currency rates, fourth quarter organic sales growth was 3%.  Fourth quarter sales for the Company's Research business grew 3% on a currency-adjusted basis, driven primarily by growth in the Asia Pacific-Latin American markets. Fourth quarter sales for the Company's SAFC business grew 4% on a currency-adjusted basis, as sales of our Supply Solutions, Bioscience and Hitech products again reflected stronger demand. A reconciliation of reported to adjusted (organic) sales is below.

The operating income margin in the fourth quarter of 2010 was 22.3% of sales, comparable to that reported for the fourth quarter of 2009. Excluding restructuring costs, the operating income margin in the fourth quarters of 2010 and 2009 would have been 24.2% and 23.9%, r
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