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Sigma-Aldrich (Nasdaq: SIAL) Reports 16.7% Gain in Q2 2008 Diluted EPS. Q2 2008 Sales Rise 14.4%. 2008 Diluted EPS Forecast Raised $.05 to $2.62-$2.72.
Date:7/22/2008

tion of strategically important products, services, platform technologies, businesses and facilities.

Our forecast for diluted earnings per share for all of 2008 is increased by $.05 to a new range of $2.62 to $2.72, a 12.0% to 16.2% increase over 2007's $2.34, based on our 2008 year-to-date results, the sales expectations described above, currency rates remaining at June 30, 2008 levels, the expected pretax income margin and tax rate described below and other expectations for our business. Pretax income margins for the full year are expected to improve from the 21.5% achieved in 2007 as the result of favorable currency rates, lower interest rates, modest contributions from the Company's supply chain initiative and other margin improvement initiatives. Anticipated input cost increases are expected to be offset by higher selling price increases, with ongoing monitoring of these costs to achieve desired margins. A higher forecasted effective tax rate in the range of 30% to 32% of pretax income for all of 2008 will likely partially offset pretax margin improvements. The effective tax rate for 2008 is expected to increase due to a higher net international tax level versus 2007 and the expiration of the U.S. R&D tax credit. Reinstatement of the U.S. R&D tax credit by the U.S. Congress and/or other known tax reduction activities could drive the tax rate for 2008 from our higher year-to-date level to the mid-point or lower end of the forecasted range. Variations to our forecast tax rate and forecast diluted EPS for 2008 are also possible due in part to changes in the status of tax uncertainties pursuant to FASB Interpretation No. 48, "Accounting for Uncertainty in Income Taxes." Additional modest share repurchase activity may also benefit EPS growth.

Supply Chain Initiative: The Company's previously announced supply chain project is an ambitious five-year project that is expected to improve service and enable us to expand margins through eight separate but co
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