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Sigma-Aldrich (Nasdaq: SIAL) Q3 2007 Sales Increase 14.0%, Yielding Diluted EPS of $.54.
Date:10/23/2007

(45.1) (41.9)

Treasury stock purchases (131.4) (125.0)

Exercise of stock options 24.9 21.1

Excess tax benefits from stock-based

payments 5.5 2.4

Net cash used in financing activities (123.7) (120.0)

Effect of exchange rate changes on cash 8.1 3.7

Net change in cash and cash equivalents 29.0 38.4

Cash and cash equivalents at January 1 173.8 98.6

Cash and cash equivalents at March 31 $202.8 $137.0

SIGMA-ALDRICH CORPORATION

Supplemental Financial Information - (Unaudited)

Sales Growth by Business Unit

Three Months

Ended September 30, 2007

Currency Adjusted

Reported Impact Acquisition (Organic)

Research Essentials 8.6% 4.2% -% 4.4%

Research Specialties 13.6% 4.8% -% 8.8%

Research Biotech 11.2% 4.0% -% 7.2%

SAFC 19.8% 4.0% 9.7% 6.1%

Total 14.0% 4.3% 2.7% 7.0%

Nine Months

Ended September 30, 2007

Currency Adjusted

Reported Impact Acquisition (Organic)

Research Essentials 8.3% 3.9% -% 4.4%

Research Specialties 13.0% 4.4% -% 8.6%

Research Biotech 7.0% 3.6% -% 3.4%

SAFC 20.0% 4.0% 7.5% 8.5%

Total 1
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SOURCE Sigma-Aldrich
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