Navigation Links
Sigma® Life Science and King's College London Co-Developing miRNA Target Identification Technology
Date:5/5/2011

ST. LOUIS, Mo., May 5, 2011 /PRNewswire/ -- Sigma Life Science, the innovative biological products and services research business of Sigma-Aldrich® (Nasdaq:  SIAL), and King's College London, today announced an exclusive license to develop and commercialize new technology for the identification and validation of microRNA (miRNA) targets in research and clinical diagnostics. For more detailed information, visit www.wherebiobegins.com/targetid.

miRNAs function as critical regulators of gene expression in eukaryotic cells, with more than 1,000 different miRNAs in the human genome already known to play multiple roles in gene regulation. Although the specific targets of most miRNAs are largely unknown, aberrant expression of miRNAs has been implicated in numerous disease states, making them important targets for clinical research in oncology, wound healing and infectious disease.

Currently, identification of miRNA targets is laborious and inefficient, relying on computer algorithms and subsequent validation by in vitro assays. To overcome this research bottleneck, scientists in the Division of Cancer Studies at King's have developed a technology allowing simple, accurate identification and validation of miRNA targets. Dr. Joop Gaken, lead researcher of this project, explained, "The role of miRNAs in cancer is well established, and several miRNAs clearly function as either oncogenes or tumor suppressor genes, although the target genes are unknown in the majority of cases. This new test is expected to enable the straightforward identification of target genes that are strongly regulated by a given miRNA, helping to elucidate important gene regulation events in vivo."

"miRNA research is a rapidly growing field, and this test is expected to be an invaluable asset to commercial and academic researchers working with miRNAs," said Steven Suchyta, Market Segment Manager at Sigma-
'/>"/>

SOURCE Sigma Life Science
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Sigma® Life Science Enters Genetically Modified Cell Market
2. Sigma® Life Science Awarded Silver in Top Ten Innovations 2010
3. Sigma® Life Science Creates Worlds First Knock-in Rats using Zinc Finger Nuclease Technology
4. Sigma® Life Science Launches Pre-designed CompoZr® Knockout Zinc Finger Nucleases for Entire Human Genome
5. Sigma® Life Science Launches Suite of Knockout Rats to Model Parkinsons Disease
6. Sigma® Life Science Joins AMDeCs Vendor Partnership Program, Further Enhancing Value to Academic Medical Research Centers
7. Sigma® Life Science and Kraig Biocraft Laboratories to Develop Silkworms for the Production of Spider Silk
8. The Science of Music Meets the Art of Medicine - ARIMM 3rd Annual Conference at IPFW, September 12-13, 2008
9. Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2008
10. Carna Biosciences Signs Reagent Supply Agreement with Caliper Life Sciences
11. Pressure BioSciences, Inc. to Discuss Second Quarter 2008 Financial Results and Provide Business Update
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2015)... CA (PRWEB) April 23, 2015 Delpor, ... today announced that the United States Patent and Trademark ... Company’s NANOPOR™ technology. US Pat. No. ... Delpor’s microfabricated drug delivery device for the ... proprietary NANOPOR™ technology for the sustained (zero-order) release of ...
(Date:4/22/2015)... , April 22, 2015 /PRNewswire/ - BioAmber Inc. (NYSE and EURONEXT Paris:BIOA) today ... first quarter 2015 on Thursday, May 7, 2015 after ... a webcast and conference call for 4.30 pm ET ... Live audio of the conference call will be ... investors, members of the news media and the general ...
(Date:4/22/2015)... Calif. , April 22, 2015 ... and analytics, announced today that it has opened ... its continued growth and expansion.  The common stock ... Act, Section 506(c), a law intended to encourage ... regulations.  Prior to 506(c), small businesses largely relied ...
(Date:4/22/2015)... 2015 /PRNewswire/ - Portage Biotech Inc. ("Portage") (OTC Market: ... announce that Biohaven Pharmaceutical Holding Company Limited (Biohaven), ... to initiate a Phase 1 pharmacokinetic and biomarker ... Biohaven plans to initiate the trial no later ... in the Phase 1 study, Biohaven will move ...
Breaking Biology Technology:Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 2Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 3BioAmber Announces Webcast of Fiscal First Quarter 2015 Financial Results 2Steep Hill Launches $5M Limited Stock Offering 2Steep Hill Launches $5M Limited Stock Offering 3Portage's Biohaven to begin Phase 1 study in 3Q2015 and readying for Phase 3 study start by 1Q2016 2Portage's Biohaven to begin Phase 1 study in 3Q2015 and readying for Phase 3 study start by 1Q2016 3
... SHENYANG, China, Aug. 20 /Xinhua-PRNewswire-FirstCall/ -- 3SBio ... biotechnology company focused on,researching, developing, manufacturing and ... Annual General Meeting of,Shareholders of 3SBio Inc. ... (Friday) at,10:00 a.m. (Beijing time) at No.3 ...
... Medication Management Systems,(MMS) today announced a new ... -- the result of a legislative initiative ... benefit for North,Dakota state employees and other ... Care System(TM) will provide North Dakota,pharmacists with ...
... Aug. 20 Pressure,BioSciences, Inc. (Nasdaq: PBIO ... for sale of ProteoSolve-SB, a novel, pressure cycling,technology ... of nucleic acids (DNA and RNA), proteins, and,lipids ... laboratory research.,This patent-pending kit was released earlier this ...
Cached Biology Technology:3SBio Inc. to Hold Annual General Meeting 2North Dakota Pharmacists and Medication Management Systems Partner to Deliver Quality MTM Services to Patients With Diabetes 2Pressure BioSciences, Inc. Releases Novel, PCT-dependent Sample Preparation Kit for Systems Biology Studies 2Pressure BioSciences, Inc. Releases Novel, PCT-dependent Sample Preparation Kit for Systems Biology Studies 3Pressure BioSciences, Inc. Releases Novel, PCT-dependent Sample Preparation Kit for Systems Biology Studies 4
(Date:4/20/2015)... 2015 Huntington Memorial Hospital is the first ... new miniaturized, wireless monitoring sensor to manage heart failure ... only FDA-approved heart failure monitoring device that has been ... physicians to manage heart failure. The CardioMEMS ... the pulmonary artery (PA) during a non-surgical procedure to ...
(Date:4/14/2015)... YORK , April 14, 2015  HYPR ... IDentity Online (FIDO ® ) Alliance tm , ... specifications. FIDO members commit to share technology and ... methods that are interoperable, more secure and private, ... enable biometric identity verification that protects sensitive user ...
(Date:4/13/2015)... , April 13, 2015  higi, a leading ... ways to more fully engage with their communities around ... industry-leading, privacy protected and secure API.  ... enables the most accessible, affordable, and convenient vehicle to ... The API will allow ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3
... A new analysis of extinct sea creatures suggests that the ... that allowed these ancient species to adapt to and thrive ... this week in the journal Nature by scientists ... report that the evolution of live-born young depended crucially on ...
... some individuals in the vegetative and minimally conscious states, ... learn and thereby demonstrate at least a partial consciousness. ... online edition of Nature Neuroscience . It ... patients in vegetative and minimally conscious states can learn. ...
... first drink may influence genes linked to alcoholism, making the ... team of researchers, led by scientists at Washington University School ... Australia. They wanted to learn whether twins who start drinking ... more heritable form of alcohol dependence than those who begin ...
Cached Biology News:Genetic sex determination let ancient species adapt to ocean life 2Scientists find that individuals in vegetative states can learn 2Young age at first drink may affect genes and risk for alcoholism 2Young age at first drink may affect genes and risk for alcoholism 3