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Shire's Replenished Portfolio Drives Excellent Quarterly Performance
Date:4/29/2010

ALDA/MEZAVANT(R) (up 29% to $64 million, CER: up 28%); and - Recently launched INTUNIV(R) ($35 million) and VPRIV(R) ($6 million). - Product sales including ADDERALL XR(R) were down 5% to $718 million (CER: down 7%), as the decline in ADDERALL XR sales compared to Q1 2009 (down 69% to $92 million) offset the strong core product sales growth. The decline in ADDERALL XR product sales was expected, as Q1 2009 was the last quarter of ADDERALL XR exclusivity prior to the launch of authorized generic versions by Teva Pharmaceuticals USA Inc. ("Teva") in April 2009 and Impax Laboratories Inc. ("Impax") in October 2009. - Total revenues of $816 million remained at 2009 levels (CER: down 2%; 2009: $818 million) as higher royalty income (primarily received on Impax's sales of authorized generic ADDERALL XR) offset lower product sales. - Non GAAP operating income decreased by 19% to $265 million (2009: $327 million) as a result of increased investment in research and development ("R&D") and higher selling, general and administrative ("SG&A") costs in support of recent product launches. On a US GAAP basis, operating income decreased by 4% to $218 million (2009: $226 million). US GAAP operating income in Q1 2009 included costs of $65 million on termination of the Women's Health development agreement with Duramed Pharmaceuticals Inc. ("Duramed"). - Cash generation, which is a Non GAAP measure, continues to be strong and increased by 19% to $278 million in Q1 2010 (2009: $234 million). The increase in cash generation in 2010 resulted from higher cash receipts from gross product sales and royalties, partially offset by higher cash payments on the increased investment in R&D and SG&A. Cash balances (including cash equivalents and restricted cash) at March 31, 2010 were $684 million (December 31, 2009: $532 millio
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SOURCE Shire plc
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