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Shire's Quarterly Revenues Grow by 25% to $1 Billion for the First Time
Date:7/28/2011

t of an international commercial hub in Switzerland, gain on disposal of the investment in Virochem ($11.1 million), and tax effect of adjustments; and

(d)    Depreciation: Depreciation of $46.4 million included in Cost of product sales, R&D costs and SG&A costs for US GAAP separately disclosed for the presentation of Non GAAP earnings.

Unaudited results for the three months and six months to June 30, 2011

Non GAAP reconciliation

The following table reconciles US GAAP net cash provided by operating activities to Non GAAP cash generation:

3 months to June 30, 6 months to June 30, 2011 2010 2011 2010 $M $M $M $M Net cash provided by operating activities 283.6 283.8 485.5 469.9 Tax and interest payments, net 156.4 127.6 162.8 217.7 Non GAAP cash generation 440.0 411.4 648.3 687.6

The following table reconciles US GAAP net cash provided by operating activities to Non GAAP free cashflow:

3 months to June 30, 6 months to June 30, 2011 2010 2011 2010 $M $M $M $M Net cash provided by operating activities 283.6 283.8 485.5 469.9 Capital expenditure (1) (48.5) (45.3) (95.0) (88.9) Non GAAP free cash flow 235.1 238.5 390.5 381.0

(1) Capital expenditure for the three months and six months ended June 30, 2010 excludes capital expenditure relating to the acquisition of Lexington Technology Park.

Non GAAP net debt comprises:

June 30, December 31, 2011 2010 $M $M Cash and cash equivalents 144.6 550.6 Restricted cash 21.9 26.8 Convertible bonds (1,100.0) (1,100.0) Revolving credit facility (30.0) - Building finance obligation (8.4) (8.4) Non GAAP net debt (971.9) (531.0)

NOTES TO EDITORS

THE "SAFEHARBOR" STATEMENT UNDER THE PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995

Statements included herein that are not historical facts are forward-looking statements. Such forwar
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SOURCE Shire plc
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