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Shire's Quarterly Revenues Grow by 25% to $1 Billion for the First Time
Date:7/28/2011

preciation of $29.5 million included in Cost of product sales, R&D costs and SG&A costs for US GAAP separately disclosed for the presentation of Non GAAP earnings.

Unaudited results for the three months to June 30, 2010

Non GAAP reconciliation

US GAAP Adjustments Divestments, Amortization reorganizations & asset & discontinued 3 months to, June 30, impairments operations 2010 (a) (b) $M $M $M Total revenues 849.4 - - Costs and expenses: Cost of product sales 119.1 - (7.4) Research and development 147.0 - - Selling, general and administrative 354.4 (33.8) - Gain on sale of product rights (4.1) - 4.1 Reorganization costs 8.6 - (8.6) Depreciation - - - Total operating expenses 625.0 (33.8) (11.9) Operating income 224.4 33.8 11.9 Interest income 0.5 - - Interest expense (8.3) - - Other expense, net (2.6) - - Total other expense, net (10.4) - - Income before income taxes and equity in earnings of equity method investees 214.0 33.8 11.9 Income taxes (54.5) (9.6) (1.9) Equity in earnings of equity method investees, net of tax 1.0 - - Net income 160.5 24.2 10.0 Impact of convertible debt, net of tax 8.4 - - Numerator for diluted EPS 168.9 24.2 10.0 Weighted average number of shares (millions) - diluted 590.0 - - Diluted earnings per ADS 85.8c 12.3c 5.1c

(Continued)

Adjustments Non GAAP Reclassify 3 months to, depreciation June 30, 2010 (c) $M $M Total revenues - 849.4 Costs and expenses: Cost of product sales (3.8) 107.9 Research and development (3.5) 143.5 Selling, general and administrative (16.6) 304.0 Gain on sale of product rights - - Reorganization costs - - Depreciation 23.9 23.9 Total operating expenses - 579.3 Operating income - 270.1 Interest income - 0.5 Interest expense - (8.3) Other expense, net - (2.6) Total other expense, net - (10.4) Income before income taxes and equity in earnings of equity method investees - 259.7 Income taxes - (66.0) Equity in earnings of equity method inve
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SOURCE Shire plc
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