Shire's New Product Portfolio Delivers Strong Quarterly P...(ase)/decrease in other assets ...)

assets (51.1) 0.6 (53.5) 1.3

Increase/(decrease) in accounts

and notes payable and other

liabilities 56.7 96.1 (9.7) 103.8

Increase/(decrease) in deferred

revenue 1.9 (42.9) 7.4 45.6

Return on investment on joint

ventures 7.1 6.8 7.1 6.8

-------- -------- -------- --------

Net cash provided by operating 279.4 123.7 525.5 408.1

activities(A)

-------- -------- -------- --------

Unaudited US GAAP results for the three months and nine months to September 30, 2008

Consolidated Statements of Cash Flows

3 months 3 months 9 months 9 months

to to to to

September September September September

30, 30, 30, 30,

2008 2007 2008 2007

$M $M $M $M

-------- -------- -------- --------

CASH FLOWS FROM INVESTING

ACTIVITIES:

Movements in short-term

investments - - - 55.8

Movements in restricted cash 2.5 (2.4) 7.7 (12.0)

Purchases of subsidiary

undertakings, net of cash acquired (462.5) - (462.5) (2,458.6)

Expenses related to the New River

acquisition - - - (60.4)

Purchases of long-term investments (0.2) (50.9) (1.
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