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Shire's New Product Portfolio Delivers Strong Quarterly Performance
Date:10/29/2008

ge 120.5 - 255.5 1,896.0

-------- ------- -------- --------

Total operating expenses 655.7 586.1 2,037.8 3,323.1

-------- ------- -------- --------

Operating income/(loss) 122.9 22.6 218.6 (1,611.3)

Interest income 3.8 8.0 23.0 42.7

Interest expense (19.9) (18.0) (54.0) (53.8)

Other (expenses)/income, net (52.0) (1.6) (38.6) 0.7

-------- ------- -------- --------

Total other (expenses)/income, net (68.1) (11.6) (69.6) (10.4)

-------- ------- -------- --------

Income/(loss) from continuing operations

before income taxes, minority interests

and equity in earnings of equity method

investees 54.8 11.0 149.0 (1,621.7)

Income taxes (45.0) 23.2 (89.3) (43.9)

Minority interest 1.3 - 1.3 -

Equity in earnings of equity method

investees, net of taxes 1.6 0.5 1.3 1.7

-------- ------ -------- --------

Income/(loss) from continuing

operations 12.7 34.7 62.3 (1,663.9)

Loss from discontinued operations (0.9) - (0.9) -

-------- ------ -------- --------

Net income/(loss) 11.8 34.7 61.4 (1,663.9)

-------- ------- -------- --------

(1) For the three months to September 30, 2007 $4.6 million of depreciation was reclassified from Selling,
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SOURCE Shire Plc
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