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Shire plc Appoints Two New Board Directors
Date:6/17/2010

ds and a Member of Law Society of Scotland. Anne Minto has also been appointed to Shire's Remuneration Committee and she will assume the Chair of that Committee on the retirement of Kate Nealon from the Shire Board at the end of Ms Nealon's term of office at the end of July.

Shire Chairman, Matthew Emmens commented: "I am very pleased that we have attracted two highly qualified and experienced Directors to our Board. David's medical background and areas of specializm and Anne's legal, commercial and remuneration experience will be welcome additions to our strong team. I'd like to thank Kate Nealon for her four years of service to Shire's Board and for her contributions to the Remuneration Committee."

There is no further information that is required to be disclosed under 9.6.13R of the United Kingdom listing rules

Notes to editors

SHIRE PLC

Shire's strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit hyperactivity disorder (ADHD), human genetic therapies (HGT) and gastrointestinal (GI) diseases as well as opportunities in other therapeutic areas to the extent they arise through acquisitions. Shire's in-licensing, merger and acquisition efforts are focused on products in specialist markets with strong intellectual property protection and global rights. Shire believes that a carefully selected and balanced portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.

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