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Shire plc: Strong Third Quarter and Increased Non GAAP Earnings Expectations
Date:10/24/2013

T on October 24, 2013:

UK dial in:                0808-237-0030 or 0203-139-4830

US dial in:                1-866-928-7517 or 1-718-873-9077

International Access Numbers: http://wpc.1726.planetstream.net/001726/FEL_Events_International_Access_List.p

Password/Conf ID:            71566006#

Live Webcast:                http://www.shire.com/shireplc/en/investors

The quarterly earnings presentation will be available today at 13:00 BST / 08:00 EDT on:

- Shire's IR Briefcase in the iTunes Store

- Shire.com Investors section

OVERVIEW OF THIRD QUARTER 2013 FINANCIAL RESULTS

1.    Product sales

For the three months to September 30, 2013 product sales increased by 13% to $1,195 million (Q3 2012: $1,055 million) and represented 97% of total revenues (Q3 2012: 96%).

US Exit Market Year on year growth Share(1) Non GAAP Product sales Sales $M Sales CER US Rx(1) VYVANSE(2) 299.2 +21% +21% +7% 17% LIALDA/MEZAVANT 141.9 +36% +36% +23% 27% ELAPRASE 129.1 +17% +17% n/a(3) n/a(3) REPLAGAL 108.5 -11% -10% n/a(4) n/a(4) VPRIV 87.8 +17% +17% n/a(3) n/a(3) ADDERALL XR 81.4 -20% -20% -2% 5% INTUNIV 80.8 +17% +17% +8% 4% PENTASA(R) 70.6 +5% +5% +1% 14% FIRAZYR 62.6 +107% +106% n/a(3) n/a(3) DERMAGRAFT 23.9 -29% -29% n/a(3) n/a(3) OTHER 109.1 +16% +15% n/a n/a Total 1,194.9 +13% +13%

  1. Data provided by IMS Health National Prescription Audit ("IMS NPA") relates solely to US-based prescriptions. Exit market share represents the average monthly US market share in the month ended September 30, 2013.
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SOURCE Shire plc
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