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Shire plc: IFRS Results for the Year Ending December 31, 2007
Date:3/25/2008

US$M US$M

_______ _________ _________

Continuing operations:

Revenue 2,436.3 1,796.5

Cost of sales (312.7) (252.9)

__________ __________

Gross profit 2,123.6 1,543.6

Research and development (including other

intangible asset impairments of US$256.4

million (2006: US$nil)) (775.2) (295.8)

Selling, general and administrative

(including goodwill and other intangible

asset impairments of US$134.1 million (2006: (1,381.1) (1,219.9)

US$273.0 million)

Gain on sale of product rights 102.9 63.0

__________ __________

Operating profit 70.2 90.9

Investment revenues 50.6 50.5

Finance costs (93.1) (27.0)

Other income/(expense), net 1.9 9.4

Share of post tax profit from associates and

joint ventures 1.8 5.8

__________ __________

Profit before taxation 31.4 129.6

Taxation 4 51.0 (114.0)

__________ __________

Profit for the year from continuing

Operations 82.4 15.6

Discontinued operations:

Gain on disposal of discontinued operation,

net of tax
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SOURCE Shire plc
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