Navigation Links
Shire plc: Excellent Performance Across All Areas of the Business and Accelerating New Product Sales Drive Revenue Growth of 36%
Date:2/21/2008

ican Federal Commission for the Protection against Sanitary Risk. ELAPRASE is now approved in 37 countries worldwide and sales for the year to December 31, 2007 were $181.8 million (2006: $23.6 million).

- In October 2007 ELAPRASE was launched in Japan, with sales and distribution managed by Genzyme Corporation. Shire's gross profit on the arrangement equates to an effective royalty of approximately 25% to 30%, but revenues will be recorded within product sales.

- REPLAGAL(R) - Fabry disease.

- REPLAGAL is now approved in 41 countries and sales for 2007 were up 22% to $143.9 million (2006: $117.7 million).

- In February 2007 REPLAGAL was launched in Japan through Shire's partner Dainippon Sumitomo Pharma Co., Ltd. Similar to ELAPRASE, Shire will record revenues within product sales.

Pipeline Highlights

Shire has expanded its product pipeline by in-licensing the following drug compounds and technologies in 2007:

- JUVISTA(R)

- In August 2007 Shire acquired exclusive rights to develop and commercialize JUVISTA worldwide (with the exception of EU member states) from Renovo Limited ("Renovo"). JUVISTA, which is being investigated for the prevention and reduction of scarring in connection with surgery, is in late Phase 2 development.

- Seven Phase 2 efficacy trials for JUVISTA have now been reported of which six demonstrated statistically significant efficacy. Phase 2 clinical trials in multiple other surgery types are ongoing and are expected to report during 2008 and 2009.

- Pharmacological chaperone compounds for Lysosomal Storage Disorders ("LSDs") - In November 2007 Shire in-licensed from Amicus Therapeutics, Inc. ("Amicus") the rights to three compounds in markets outside the US:

- AMIGAL(TM) for Fabry disease (Phase 2) received orphan drug designation by the EMEA, which may provide it with up to ten years market exclusivity in the EU;

- PLICERA(TM) for Gaucher disease (Phase 2) rec
'/>"/>

SOURCE Shire plc
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

Related biology technology :

1. Shire plc: Correction Re Website
2. Shires ELAPRASE(R) (idursulfase) Approved in Mexico for Treatment of Hunter Syndrome
3. Shire Engages Palio
4. Texas Boy Receives Wheelchair From New Hampshire Couples Recently Deceased Granddaughter
5. FDA Approves Additional Dosage Strengths of Shires ADHD Treatment VYVANSE(TM) (lisdexamfetamine dimesylate) Which May Help Physicians Tailor Treatment for Individual Patients
6. Shire Expands its Gastrointestinal Portfolio Through In-Licensing Celiac Disease Phase 2 Product From Alba Therapeutics Corporation
7. Alba Therapeutics Corporation and Shire plc Enter Into $325 Million ex-US, ex-Japan Licensing Agreement to Develop and Commercialize AT-1001
8. Shire plc: Board Changes
9. David Mott Appointed Non Executive Director at Shire
10. Correction: Shire plc: Third Quarter 2007 results date notification November 1, 2007
11. Shire Divests Non-Core Product Portfolio to Almirall
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2008)...es embedded with a telescope,promise to make it ea...do,other activities requiring sharper distance vis...scribe the advantages of these innovative glasses,...e May/June issue of,Journal of Biomedical Optics, ..."This new design has several advantages," says the...
(Date:7/24/2008)...ll/ -- American Oriental,Bioengineering, Inc. (NYS...,second quarter 2008 financial results on Monday, ...mpany will hold a conference call at 5:00 pm ET on...ter 2008 results. Listeners may,access the call by...rnational callers, access code: 41757592. A webcas...
(Date:7/24/2008).../- Poniard,Pharmaceuticals,...y focused,on oncology, today announced that it wil...second quarter results and provide a corporate upd...nt plan for picoplatin, the,Company,s lead product...ef,executive officer, Ronald A. Martell, president...
(Date:7/24/2008).../ -- Sagent Pharmaceuticals, Inc.,a privately-hel...d that it,has launched ceftazidime for injection, ...ntibiotic. Sagent will offer ceftazidime in 1,and ...vials. According to,IMS data, 2007 sales of inject...ately $45.7 million., "Sagent is proud to be prov...
Breaking Biology Technology:Telescope Embedded in Spectacle Lens Promises to Make Driving Easier for Visually Impaired 2Telescope Embedded in Spectacle Lens Promises to Make Driving Easier for Visually Impaired 3Poniard Pharmaceuticals to Host Second Quarter 2008 Financial Results Conference Call on July 31 2Sagent Pharmaceuticals Launches Ceftazidime for Injection, USP 2
...WR , ECL™ Semi-dry Blotters are desi...er results using low current and voltage with a mi...s available with and without built-in power suppli... Complete, uniform electrotransfer of proteins f... • Minimal buffer use—just enough...
...phopeptide • two-dimensional liquid chromatog...ull; reversed-phase chromatography (RPC) • st...inear ion trap mass spectrometer, , ... phospho-peptides in mouse brain tissue. The tryps...exchange chromatography (SCX), followed by reverse...
...onucleus assays • toxicology • image ana...icronucleus induction is a key characteristic of g...mation resulting from DNA strand breakage (clastog...aneugens) is an important component of toxicology ...f micronucleus assays is time consuming and subjec...
...nalyzer • apoptosis • multiplexing ...tosis represents a gene-directed, morphologically ... death. Inappropriate control of apoptosis is asso...ncer, AIDS, neurodegenerative diseases, and ischae...optosis is extremely important when considering th...
Other Biology Technology:ECL Semi-dry Blotters 22D-LC analysis of phosphopeptides in brain tissue using Ettan MDLC and Finnigan LTQ 22D-LC analysis of phosphopeptides in brain tissue using Ettan MDLC and Finnigan LTQ 32D-LC analysis of phosphopeptides in brain tissue using Ettan MDLC and Finnigan LTQ 42D-LC analysis of phosphopeptides in brain tissue using Ettan MDLC and Finnigan LTQ 52D-LC analysis of phosphopeptides in brain tissue using Ettan MDLC and Finnigan LTQ 6Analysis of in vitro micronucleus assays using the IN Cell Analyzer 3000 Micronuclei Formation Analysis Module 2Analysis of in vitro micronucleus assays using the IN Cell Analyzer 3000 Micronuclei Formation Analysis Module 3Analysis of in vitro micronucleus assays using the IN Cell Analyzer 3000 Micronuclei Formation Analysis Module 4Analysis of in vitro micronucleus assays using the IN Cell Analyzer 3000 Micronuclei Formation Analysis Module 5The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays 2The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays 3The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays 4The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays 5The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays 6The measurement of DNA condensation and mitochondrial changes during apoptosis and necrosis in cell based assays 7
(Date:7/23/2008)...enewable fuel source could generate enough electri...,s entire consumption needs and lead to a signific...according to US research published today, Thursday...ntal Research Letters . , The journal paper, ,Co...erting Manure to Biogas, has implications for all...
(Date:7/23/2008)...llectively spend about $1 billion annually could p...ic tons of carbon dioxide per year for the next 25...about that much money to put an end to a tenth of ...e top contributors to greenhouse gas emissions, re...rogram could have potential to reduce global carbo...
(Date:7/23/2008)...ernationally renowned scientists from 12 countries...lia and India to address ancient microscopic foss...ng together the world,s best scientists in the fie...iam Schopf, founder and director of the UCLA Insti...or the Study of Evolution and the Origin of Life (...
(Date:7/23/2008)...ards and Technology (NIST) have developed a techni... in protein-based pharmaceuticals. This first syst... scientists can be assured that their instruments ...aggregates, a major concern because of its impact ...ufacturing. , Proteins, a main constituent of ma...
Breaking Biology News(10 mins):Cow power could generate electricity for millions 2Paying to save tropical forests could be a way to reduce global carbon emissions 2Paying to save tropical forests could be a way to reduce global carbon emissions 3Paying to save tropical forests could be a way to reduce global carbon emissions 4UCLA 'world summit' to explore ancient life on Earth, and beyond 2NIST trumps the clumps: Making biologic drugs safer 2Safer easier system for remote explosive detection 4506 1Safer easier system for remote explosive detection 4506 2CamelBak 28R 29 CEO Statement on BPA and Plastic Re Usable Water Bottles 16442 1Haemacure Reports on its annual general and special meeting of shareholders 16438 1Haemacure Reports on its annual general and special meeting of shareholders 16438 2Haemacure Reports on its annual general and special meeting of shareholders 16438 3Haemacure Reports on its annual general and special meeting of shareholders 16438 4Aerobic Exercise Keeps You Young 16434 1Aerobic Exercise Keeps You Young 16434 2
...y (NYUCD) research team has found the first oral b...rn Homo sapiens out of Africa to Asia. , The te... and comprehensive care at NYUCD, discovered that ...dental caries, has evolved along with its human ho...ingle common ancestor who lived in Africa between ...
...ve care unit (ICU) already are seriously ill, so t...tunately, statistics show that as many as 25 perce...on ventilators develop pneumonia, which can be fat...ause of infection in the hospital, and studies hav...ts and double the length of stay of the patient in...
...learn skills from each other, in the same manner a...mbridge researcher. , Dr Antonio Moura, a Brazilia...hropology, has discovered signs that Capuchin monk...o ward off potential predators. , While not co...evidence that suggests other species have somethin...
...l fuel air pollution in the United States by analy...nwide. , This novel way to measure carbon dioxid...ll help atmospheric scientists better understand w...es in the air. Tracking fossil-fuel-emitted carbon... the world adhere to the Kyoto Protocol, an agreem...
Other Biology News:'Ancestral eve' was mother of all tooth decay 2Bacteria from patient's dental plaque causes ventilator-associated pneumonia 2New evidence of 'human' culture among primates 2New evidence of 'human' culture among primates 3Scientists map air pollution using corn grown in US fields 2
Alpha-2-antiplasmin precursor (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Alpha-2-AP). [Source:Uniprot/SWISSPROT;Acc:P08697] Antigen: Recombinant Protein Epitope Signature Tag (PrEST).
Mouse polyclonal antibody raised against a partial recombinant CSRP3. NCBI Entrez Gene ID = 8048
Mouse monoclonal antibody raised against a partial recombinant EOMES. NCBI Entrez Gene ID = EOMES
LTQ XL Linear Ion Trap from Thermo Scientific
Biology Products: