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Shire plc: Core Portfolio of Products Delivers 20% Sales Growth
Date:8/5/2009

Page Overview of Financial Results 6 Financial Information 13 Notes to Editors 26 Safe Harbor Statement 26 Explanation of Non GAAP Measures 26 Trademarks 27

Dial in details for the live conference call for investors 14:00 BST/09:00 EDT on August 5, 2009:

    UK dial in: 0808-100-5150 or 01296-311-652
    US dial in: 1-8662977327 or 1-7183541176
    International dial in: +44(0)1296-311-652
    Password/Conf ID: 515 749#
    Live Webcast:http://www.shire.com/shire/InvestorRelations/index.jsp?tn=2
    OVERVIEW OF FINANCIAL RESULTS
    1. Introduction
    Summary of Q2 2009

Revenues from continuing operations for the three months to June 30, 2009 decreased by 19% to $629.7 million (2008: $775.6 million), primarily due to the decline in branded ADDERALL XR product sales in Q2 2009 following the launch of an authorized generic version by Teva in April 2009. Excluding ADDERALL XR, product sales increased by 20% to $491.0 million (2008: $409.3 million).

Non GAAP operating income for the three months to June 30, 2009 decreased by 53% to $115.5 million (2008: $246.5 million). The lower product sales of ADDERALL XR in Q2 2009 were partially offset by higher revenues from other products and lower operating expenses, as the Company benefits from its more diversified portfolio and continues to focus on cost management, with some additional benefits from foreign exchange compared to 2008.

US GAAP operating income from continuing operations for the three months to June 30, 2009 increased by $102.0 million to $34.7 million (2008: $67.3 million loss). US GAAP operating in
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SOURCE Shire Plc
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