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Shire plc: Core Portfolio of Products Delivers 20% Sales Growth
Date:8/5/2009

both recurring and non-recurring, that Shire's management believes are not related to the core performance of Shire's business. A list of these items can be found on pages 26-27.

PRODUCT LAUNCHES

Subject to obtaining the relevant regulatory/governmental approvals, product launches planned over the next two years include:

    - MEZAVANT for the treatment of ulcerative colitis; launches will
      continue in certain EU and RoW countries in 2009 and 2010;

    - FIRAZYR for the symptomatic treatment of acute attacks of HAE; launches
      will continue in certain European and Latin American countries during
      2009 and 2010;

    - INTUNIV for the treatment of ADHD in children and adolescents in the
      US in the fourth quarter of 2009;

    - EQUASYM(R) for the treatment of ADHD; launches will continue in certain
      EU countries during 2009 and 2010;

    - DAYTRANA(R) for the treatment of ADHD in adolescents in the US in 2010;

    - Velaglucerase alfa for the treatment of Gaucher disease in the US and
      the EU in 2010; and

    - VYVANSE for the treatment of ADHD, in ex-US and ex-EU regions starting
      in 2010, and in the EU in 2011.

DIVIDEND

In respect of the six months ended June 30, 2009, the Board resolved to pay an interim dividend of 2.147 US cents per ordinary share (2008: 2.147 US cents per share).

Dividend payments will be made in Pounds Sterling to Ordinary shareholders and in US Dollars to holders of American Depository Shares ("ADS"). A dividend of 1.302 pence per ordinary share (2008: 1.085 pence) and 6.441 US cents per ADS (2008: 6.441 US cents) will be paid on October 8, 2009 to persons whose names appear on the register of members of the Company at the close of business on September 11, 2009.

    Additional Information
    The following additional information is included in this press release:

      
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SOURCE Shire Plc
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