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Shire plc: Continued Strong Product Sales Performance in Q3: On Track to Deliver Significant 2011 Earnings Growth
Date:10/28/2011

ncluded the up-front payment to Acceleron and the intangible asset impairment charges for DAYTRANA. Taken together, these costs increased the US GAAP tax rate in Q3 2010 as they were either incurred in territories with tax rates lower than Shire's effective rate or in territories where the establishment of valuation allowances precluded the recognition of any tax benefit. Were the impact of these items excluded the effective tax rate in Q3 2010 would have been 24%.

FINANCIAL INFORMATION

TABLE OF CONTENTS

Page Unaudited US GAAP Consolidated Balance Sheets 11 Unaudited US GAAP Consolidated Statements of Income 12 Unaudited US GAAP Consolidated Statements of Cash Flows 14 Selected Notes to the Unaudited US GAAP Financial Statements (1) Earnings per share 16 (2) Analysis of revenues 17 Non GAAP reconciliation 19

Unaudited US GAAP financial position as of September 30, 2011
Consolidated Balance Sheets

September 30, December 31, 2011 2010 $M $M ASSETS Current assets: Cash and cash equivalents 276.4 550.6 Restricted cash 21.0 26.8 Accounts receivable, net 844.7 692.5 Inventories 325.9 260.0 Deferred tax asset 179.0 182.0 Prepaid expenses and other current assets 159.3 168.4 Total current assets 1,806.3 1,880.3 Non-current assets: Investments 30.1 101.6 Property, plant and equipment, net 918.8 853.4 Goodwill 596.2 402.5 Other intangible assets, net 2,561.7 1,978.9 Deferred tax asset 109.5 110.4 Other non-current assets 43.0 60.5 Total assets 6,065.6 5,387.6 LIABILITIES AND EQUITY Current liabilities: Accounts payable and accrued expenses 1,312.7 1,239.3 Convertible bonds 1,100.0 - Deferred tax liability 4.3 4.4 Other current liabilities 56.0 49.6 Total current liabilities 2,473.0 1,293.3 Non-current liabilities: Convertible bonds - 1,100.0 Deferred tax liability 540.4 352.1 Other non-current liabilities 97.5 190.8 Total liabilities 3,110.9 2,936.2 Equity: Common stock of 5p par va
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