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Shire and Boston Children's Hospital Enter Into Broad Research Collaboration
Date:11/20/2012

LEXINGTON, Massachusetts, November 20, 2012 /PRNewswire/ --

Shire plc (LSE: SHP, NASDAQ: SHPG) and Boston Children's Hospital today announced a three-year, broad research collaboration in rare diseases.  The goal of the collaboration is to develop novel therapies to treat a number of rare pediatric diseases with high unmet medical need, thereby leveraging Boston Children's research expertise and Shire's development and commercialization capabilities. The partnership underscores Shire's long-term commitment to bring innovative therapies to patients with rare diseases worldwide.

Under the terms of the agreement, Shire will make an initial upfront payment to Boston Children's and will have the opportunity to fund selected research programs. The emphasis will be on opportunities that have the potential to deliver a development candidate in less than three years from project initiation. Following the completion of these programs, Shire will have an exclusive option to enter into a licensing agreement for each program. Upon entering into any subsequent licensing agreement, Boston Children's will be eligible to receive certain development and commercial milestone payments, as well as royalties on product sales from Shire. Shire will have the primary responsibility for any further clinical development and commercialization of products arising from the collaboration. The agreement, negotiated on the Boston Children's side by its Technology & Innovation Development Office, represents a flexible structure that aligns the parties according to their strengths.

"As a leader in rare diseases, Shire is pleased to enter into this innovative collaboration with Boston Children's, which joins together leaders in academia and industry to advance pioneering research from the lab to the clinic," said Dr. Philip J. Vickers, Global Head of Research and Development,  S
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SOURCE Shire plc
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