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Shire Delivers Excellent Growth for the Year, With the new Product Portfolio Achieving Sales of $1 Billion
Date:2/19/2009

ies, or which are owned by third parties as indicated and referred to in this press release:

    Product              Active ingredient

    ADDERALL(R) XR       (mixed salts of a single-entity amphetamine)
    AMIGAL(TM)           (migalastat hydrochloride) (trademark of Amicus
                          Therapeutics ("Amicus"))
    CALCICHEW(R) range   (calcium carbonate with or without Vitamin D3)
    CARBATROL(R)         (carbamazepine - extended-release capsules)
    DAYTRANA(R)          (methylphenidate transdermal system)
    DYNEPO(R)            (epoetin delta) (trademark of Sanofi-Aventis)
    ELAPRASE(R)          (idursulfase)
    EPIVIR (R)           (lamivudine) (trademark of GlaxoSmithKline ("GSK"))
    FIRAZYR(R)           (icatibant)
    FOSRENOL(R)          (lanthanum carbonate)
    INTUNIV(TM)          (guanfacine - extended release)
    LIALDA(R)            (mesalamine)
    METAZYM(TM)          (arylsulfatase-A)
    MEZAVANT(R)          (mesalazine)
    PENTASA(R)           (mesalamine) (trademark of Ferring)
    PLICERA(TM)          (isofagomine tartrate) (trademark of Amicus)
    RAZADYNE(R)          (galantamine) (trademark of Johnson & Johnson
                          ("J&J"))
    RAZADYNE(R) ER       (galantamine) (trademark of J&J)
    REMINYL(R)           (galantamine hydrobromide) (UK and Republic of
                          Ireland)
    REMINYL(R)           (galantamine) (trademark of J&J, excluding UK and
                          Republic of Ireland)
    REMINYL XL(TM)       (galantamine hydrobromide) (UK and Republic of
                          Ireland)
    REMINYL XL(TM)       (galantamine) (trademark of J&J, excluding UK and
                          Republic of Ireland)
    REPLAGAL(R)          (agalsidase alfa)
    VYVANSE(R)           (lisdexamfetamine dimesylate)
    XAGRID(TM)           (anagrelide hydrochloride)
    ZEFFIX(R)            (lamivudine) (trademark
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SOURCE Shire Plc
Copyright©2009 PR Newswire.
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3. Shire Successfully Settles Former TKT Shareholder Appraisal Rights Litigation
4. Shires New Product Portfolio Delivers Strong Quarterly Performance
5. Change of Name to Shire plc
6. Shire Announces Holding of 81% in Jerini AG and Publication of Offer Document
7. Shire Delivers Strong Quarter: Driven by $243m of New Product Sales (+164% YOY Growth). Revenue Guidance Upgrade.
8. Shire Re-Launches ADHDSupport.com, a Virtual Road Map Providing Information, Tools and Practical Tips About Attention Deficit Hyperactivity Disorder (ADHD)
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10. Shire Ltd - Second Quarter 2008 Results Date Notification - 31 July 2008
11. Graham Hetherington Appointed Chief Financial Officer and Board Director at Shire
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