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Shire Delivers Excellent Growth for the Year, With the new Product Portfolio Achieving Sales of $1 Billion

PHILADELPHIA, Pennsylvania and DUBLIN, Ireland, February 19 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, NASDAQ: SHPGY) the global specialty biopharmaceutical company announces results for the year to December 31, 2008 - a year which has seen significant growth in Shire's new product portfolio.

    Financial Highlights

                                   Full Year 2008 (1)         Q4 2008 (1)

    Product sales                    $2.75bn    + 27%      $0.70 bn   + 7%(3)
    Product sales
     (excluding ADDERALL XR(R))      $1.65bn    + 45%      $0.43 bn  + 12%(3)
    New product sales (2)            $1.00bn   36% of      $0.27 bn    38% of
                                              product                 product
                                                sales                   sales
    Total revenues                   $3.02bn    + 24%      $0.77 bn   + 6%

    Non GAAP diluted earnings per
    ADS                              $3.86      + 36%      $1.01      + 9%
    US GAAP diluted earnings per
    ADS                              $0.86   + $8.92       $0.78     - 30%
    Dividends (in US$ terms)     9.91c per       +15%        n/a      n/a

    (1) All growth figures compare 2008 results with the same period in 2007.
        New product sales shown as a percentage of 2008 full year/Q4 total
        Product sales.

    (2) New product sales comprise DAYTRANA(R), ELAPRASE(R), FIRAZYR(R),

    (3) Q4 year-on-year product sales growth has been impacted by movements
        in foreign exchange rates - on a constant exchange rate ("CER") basis
        growth in product sales was 10%, and growth in product sales
        excluding ADDERALL XR was 18%. CER growth
SOURCE Shire Plc
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