Navigation Links
Shionogi-ViiV Healthcare Starts Phase III Trial for '572-Trii' Fixed-Dose Combination HIV Therapy
Date:2/3/2011

LONDON, Feb. 3, 2011 /PRNewswire/ -- Shionogi-ViiV Healthcare, LLC announced today that the first patient has entered the clinical study, SINGLE (ING114467), designed to support a new fixed-dose combination (FDC) therapy for the treatment of HIV.  The new investigational regimen, known as 572-Trii, will combine the investigational integrase inhibitor S/GSK1349572 ('572) and ViiV Healthcare's combination nucleoside reverse transcriptase inhibitor (NRTI) Kivexa®/Epzicom® (ABC/3TC).

"ViiV Healthcare's goal is to understand and be responsive to the needs of people living with HIV," stated Dominique Limet, Chief Executive Officer, ViiV Healthcare. "With this programme, we are seeking to create an integrase-based, once-daily fixed dose combination that helps meet  patient needs.  We know that even with the successes of current therapies, patients still need additional treatment options and we will continue to evaluate existing and pipeline compounds for new combination therapies."  

"The study of a fixed-dose combination therapy that includes '572 is a signal of Shionogi and ViiV Healthcare's confidence in the compound's potential," said Dr. Sapan Shah, President & CEO, Shionogi Inc. "We're optimistic that '572 will continue to show promise through this research and in the other ongoing Phase III studies that are evaluating it in other HIV treatment regimens."

About the Study: SINGLE (ING114467)The SINGLE study (ING114467) is a multi-centre, multinational, double-blind, two arm study designed to compare the efficacy and safety of 572-Trii ('572 plus ABC/3TC) with that of efavirenz/tenofovir/emtricitabine (EFV/TDF/FTC). This study will include approximately 800 HIV-1 infected treatment-naive patients.

The primary objective for the SINGLE study will be to demonstrate the antiviral activity of 572-Trii once-daily therapy compared to EFV/TDF/FTC over 48 weeks. Secondary objectives include the assessme
'/>"/>

SOURCE Shionogi-ViiV Healthcare, LLC
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related biology technology :

1. Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2008
2. Mindray Medical to Attend Morgan Stanley Global Healthcare Unplugged Conference
3. TVM Capital, Signet Healthcare Partners and Paul Capital Healthcare Enter into euro 26 Million Financing of SpePharm
4. Beckman Coulter to Present at the Thomas Weisel Healthcare Conference 2008
5. Beckman Coulter to Present at the Morgan Stanley Healthcare Unplugged Conference
6. 3SBio Inc. to Present at the Morgan Stanley Global Healthcare Unplugged Conference
7. Neurocrine Biosciences to Present at Thomas Weisel Healthcare Conference and the NewsMakers in the Biotech Industry Conference
8. Oridion Expands its OEM Partnerships - New Agreement with Spacelabs Healthcare
9. Varian, Inc. to Present at Thomas Weisel Partners 2008 Healthcare Conference
10. Thermage, Inc. to Present at the 2008 Thomas Weisel Partners Healthcare Conference
11. Trubion Pharmaceuticals to Present at Fall 2008 Morgan Stanley Global Healthcare Unplugged Conference in New York
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... Date: Friday, April 11, 2014 , Time: 6 p.m. – ... Warrington, Pa. , Details: The Hepatitis B Foundation, ... cure for hepatitis B and improving the quality of life ... on Friday, April 11 at Warrington Country Club in Warrington, ...
(Date:1/14/2014)... , Jan. 14, 2014 As pet owners drew up ... many of them wrote: "Take better care of my furry companion." ... designer clothes and top-brand carrying cases to take the little canine ... might also feel compelled to buy some pricey toys at the ...
(Date:1/14/2014)... 2014 iLab Solutions, the leader in core ... Director of Product Strategy. In this role, Michelle will work ... to guide in the development of iLab products. Her main ... possible benefit to the scientific community by offering the most ...
(Date:1/14/2014)... Jan. 14, 2014   Kinaxis ®, provider of RapidResponse ... sales and operations planning ( S&OP ) service, is proud ... , which will be held at the Hilton San Diego ... Kinaxis customer Elisabeth Kaszas , Director of Supply Chain ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... home of innovation for entrepreneurs, as its liberal climate and productive ... roots. With over 120 technology companies founded in Madison over the ... Magazine to place it first on the list of best ... a major project in mind when they start, such as ...
... Recently the Wisconsin Technology Network sat down with ... Council , to discuss the basic tenants and initiatives ... technology space grow. This is the first portion of ... and how the Wisconsin Technology Council is working to ...
... Inc . has introduced two new AV-ready Mediasite ... for a variety of uses. The new products, ... technology, are intended to enable customers to record ... communications, Web-based education, online training, product marketing and ...
Cached Biology Technology:The NeuronFarm works to increase reading comprehension 2The NeuronFarm works to increase reading comprehension 3The NeuronFarm works to increase reading comprehension 4WTN exclusive interview with Tom Still, Wisconsin Technology Council 2WTN exclusive interview with Tom Still, Wisconsin Technology Council 3WTN exclusive interview with Tom Still, Wisconsin Technology Council 4WTN exclusive interview with Tom Still, Wisconsin Technology Council 5Sonic Foundry announces new Mediasite products 2
(Date:4/23/2014)... today announced Sophie Martin of the University of Lausanne, ... Medal. The award acknowledges her work to understand the ... the cell. , Martin has been working for the ... the way in which the spatial organization of cells ... last 11 years, she has been using fission yeast, ...
(Date:4/23/2014)... form different types of social relationships they may ... strict dominance relations. From a cognitive perspective, understanding one,s ... daily social life ("knowing who is nice or not"). ... each other sets the stage for "political" maneuvers ("knowing ... have been published in the scientific journal Nature ...
(Date:4/22/2014)... 21, 2014) -- There are all sorts of signaling ... spread their colorful tails; satin bowbirds build specialized stick ... shiny objects; and European bitterling males show off bright ... a unique method to communicate with others. , ... "Signaling can have profound fitness implications for individuals that ...
Breaking Biology News(10 mins):EMBO Gold Medal 2014 awarded to Sophie Martin 2Ravens understand the relations among others 2Best practices in communication for the animal world 2Best practices in communication for the animal world 3
... food, air and water pathogens may get a lot easier ... University researcher and his team. , Syed Hashsham, an ... and the Center for Microbial Ecology, is developing a portable, ... agents in air, water and food. , "This ...
... patients living with heart failure and other health conditions, blood ... their condition. Often, though, chemical or physiologic changes silently cause ... what if in the future a tiny device, one the ... in the patient to monitor and detect abnormalities, and could ...
... in the thymus, where the immune system's T cells develop, ... body's thousands of proteins as "self." The research confirms ... of the immune system, and not only at the sites ... case of type 1 diabetes, or the joints in rheumatoid ...
Cached Biology News:Professors to develop hand-held pathogen testing device 2Cardiologist's 'living chip' changes science of disease monitoring 2Cardiologist's 'living chip' changes science of disease monitoring 3Cardiologist's 'living chip' changes science of disease monitoring 4Proteins anchor memories in our brain 2Proteins anchor memories in our brain 3
... The BioPrime Plus Array CGH Genomic ... that enable reproducible labeling of genomic DNA ... Available in both indirect and direct labeling ... Labeling Systems provide a flexible solution to ...
MOUSE ANTI GTP BINDING PROTEIN...
The Cellject Elecroporator is suitable for all cell types including embryo, mammalian, plant, yeast and bacterial. Its has highly user-freindly programing and can be used remotely, for example in a l...
... containing a clone of the human Topoisomerase II ... alters the topological state of nucleic acids by ... break which generates a separate DNA helix (1,2) ... passage mechanism, the enzyme can relax negatively or ...
Biology Products: