"We are very pleased to be partnering with Shimadzu, a leader in mass spectrometry and innovative technologies," said Thierry Bernard, Corporate Vice President, Global Commercial Operations at bioMerieux. "By combining Shimadzu's expertise and our unique understanding of the microbiology laboratory, bioMerieux will be the only company to provide a solution integrating mass spectrometry for bacterial ID with the market's fastest AST on VITEK® 2. This complete offer, including the new Myla™ middleware, clearly demonstrates bioMerieux's commitment to enhance productivity in the lab," he added.
*About Matrix Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry
In MALDI-TOF, the sample to be analyzed is mixed with another compound, called a matrix. The mixture is applied to a metal plate and irradiated with a laser. The matrix absorbs the laser light and vaporizes, along with the sample, in the process gaining an electrical charge (ionization).
Electric fields then guide the ions into the time of flight mass spectrometer which separates them according to 'weight' (mass) and displays the results as a series of lines (spectrum) which correspond to different fragments that have broken away from the original molecule. By analyzing the pattern of fragments it is possible to deduce the structure of the molecule.
The system proposed in this collaboration takes this further by comparing the sample spectrum to a database of spectra from a growing number of bacterial species to allow the system to accurately identify the species in question.
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