Navigation Links
Shaken, not stirred: Berkeley lab scientists spy molecular maneuvers
Date:10/27/2011

Stir this clear liquid in a glass vial and nothing happens. Shake this liquid, and free-floating sheets of protein-like structures emerge, ready to detect molecules or catalyze a reaction. This isn't the latest gadget from James Bond's arsenal -- rather, the latest research from the U. S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) scientists unveiling how slim sheets of protein-like structures self-assemble. This "shaken, not stirred" mechanism provides a way to scale up production of these two-dimensional nanosheets for a wide range of applications, such as platforms for sensing, filtration and templating growth of other nanostructures.

"Our findings tell us how to engineer two-dimensional, biomimetic materials with atomic precision in water," said Ron Zuckermann, Director of the Biological Nanostructures Facility at the Molecular Foundry, a DOE nanoscience user facility at Berkeley Lab. "What's more, we can produce these materials for specific applications, such as a platform for sensing molecules or a membrane for filtration."

Zuckermann, who is also a senior scientist at Berkeley Lab, is a pioneer in the development of peptoids, synthetic polymers that behave like naturally occurring proteins without degrading. His group previously discovered peptoids capable of self-assembling into nanoscale ropes, sheets and jaws, accelerating mineral growth and serving as a platform for detecting misfolded proteins.

In this latest study, the team employed a Langmuir-Blodgett trough a bath of water with Teflon-coated paddles at either end to study how peptoid nanosheets assemble at the surface of the bath, called the air-water interface. By compressing a single layer of peptoid molecules on the surface of water with these paddles, said Babak Sanii, a post-doctoral researcher working with Zuckermann, "we can squeeze this layer to a critical pressure and watch it collapse into a sheet."

"Knowing the mechanism of sheet formation gives us a set of design rules for making these nanomaterials on a much larger scale," added Sanii.

To study how shaking affected sheet formation, the team developed a new device called the SheetRocker to gently rock a vial of peptoids from upright to horizontal and back again. This carefully controlled motion allowed the team to precisely control the process of compression on the air-water interface.

"During shaking, the monolayer of peptoids essentially compresses, pushing chains of peptoids together and squeezing them out into a nanosheet. The air-water interface essentially acts as a catalyst for producing nanosheets in 95% yield," added Zuckermann. "What's more, this process may be general for a wide variety of two-dimensional nanomaterials."


'/>"/>
Contact: Aditi Risbud
asrisbud@lbl.gov
510-486-4861
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Related biology technology :

1. DOE to Explore Scientific Cloud Computing at Argonne, Lawrence Berkeley National Laboratories
2. Berkeley researchers find new route to nano self-assembly
3. LS9, Inc., U.C Berkeley, and JBEI Make Major Breakthrough in Cellulosic Fuels Production
4. Berkeley researchers take the lead out of piezoelectrics
5. Berkeley Lab scientists create molecular paper
6. Grove Gift Launches Translational Medicine Program at UCSF & UC Berkeley
7. Berkeley Law Survey Challenges Popular Beliefs About Hi-tech Startup Patents
8. Strange new twist: Berkeley researchers discover Möbius symmetry in metamaterials
9. Berkeley Lab scientists control light scattering in graphene
10. Berkeley Lab researchers report tandem catalysis in nanocrystal interfaces
11. Berkeley scientists pioneer nanoscale nuclear materials testing capability
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Shaken, not stirred: Berkeley lab scientists spy molecular maneuvers
(Date:10/10/2017)... International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, ... security market and how smart safety and security products impact the competitive ... Parks Associates: Smart Home Devices: Main ... "The residential security market has experienced continued ...
(Date:10/10/2017)... PA (PRWEB) , ... October 10, 2017 , ... ... year’s recipients of 13 prestigious awards honoring scientists who have ... presented in a scheduled symposium during Pittcon 2018, the world’s leading conference and ...
(Date:10/9/2017)... ... October 09, 2017 , ... At its national board meeting ... a professor in Harvard University’s Departments of Physics and Astronomy, has been selected for ... of the winning team for the 2015 Breakthrough Prize in Fundamental physics for the ...
(Date:10/7/2017)... (PRWEB) , ... October 06, ... ... years’ experience providing advanced instruments and applications consulting for microscopy and surface ... expertise in application consulting, Nanoscience Analytical offers a broad range of contract ...
Breaking Biology Technology:
(Date:4/13/2017)... 2017 According to a new market research report ... Identity Administration, and Authorization), Service, Authentication Type, Deployment Mode, Vertical, and Region ... expected to grow from USD 14.30 Billion in 2017 to USD 31.75 ... ... MarketsandMarkets Logo ...
(Date:4/6/2017)... Forecasts by Product Type (EAC), ... End-Use (Transportation & Logistics, Government & Public Sector, Utilities ... Generation Facility, Nuclear Power), Industrial, Retail, Business Organisation (BFSI), ... you looking for a definitive report on the $27.9bn ... ...
(Date:4/3/2017)...  Data captured by IsoCode, IsoPlexis Corporation,s ... statistically significant association between the potency of ... objective response of cancer patients post-treatment. The ... cancer patients will respond to CAR-T cell ... to improve both pre-infusion potency testing and cell ...
Breaking Biology News(10 mins):