Navigation Links
Shaken, not stirred: Berkeley lab scientists spy molecular maneuvers
Date:10/27/2011

Stir this clear liquid in a glass vial and nothing happens. Shake this liquid, and free-floating sheets of protein-like structures emerge, ready to detect molecules or catalyze a reaction. This isn't the latest gadget from James Bond's arsenal -- rather, the latest research from the U. S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) scientists unveiling how slim sheets of protein-like structures self-assemble. This "shaken, not stirred" mechanism provides a way to scale up production of these two-dimensional nanosheets for a wide range of applications, such as platforms for sensing, filtration and templating growth of other nanostructures.

"Our findings tell us how to engineer two-dimensional, biomimetic materials with atomic precision in water," said Ron Zuckermann, Director of the Biological Nanostructures Facility at the Molecular Foundry, a DOE nanoscience user facility at Berkeley Lab. "What's more, we can produce these materials for specific applications, such as a platform for sensing molecules or a membrane for filtration."

Zuckermann, who is also a senior scientist at Berkeley Lab, is a pioneer in the development of peptoids, synthetic polymers that behave like naturally occurring proteins without degrading. His group previously discovered peptoids capable of self-assembling into nanoscale ropes, sheets and jaws, accelerating mineral growth and serving as a platform for detecting misfolded proteins.

In this latest study, the team employed a Langmuir-Blodgett trough a bath of water with Teflon-coated paddles at either end to study how peptoid nanosheets assemble at the surface of the bath, called the air-water interface. By compressing a single layer of peptoid molecules on the surface of water with these paddles, said Babak Sanii, a post-doctoral researcher working with Zuckermann, "we can squeeze this layer to a critical pressure and watch it collapse into a sheet."

"Knowing the mechanism of sheet formation gives us a set of design rules for making these nanomaterials on a much larger scale," added Sanii.

To study how shaking affected sheet formation, the team developed a new device called the SheetRocker to gently rock a vial of peptoids from upright to horizontal and back again. This carefully controlled motion allowed the team to precisely control the process of compression on the air-water interface.

"During shaking, the monolayer of peptoids essentially compresses, pushing chains of peptoids together and squeezing them out into a nanosheet. The air-water interface essentially acts as a catalyst for producing nanosheets in 95% yield," added Zuckermann. "What's more, this process may be general for a wide variety of two-dimensional nanomaterials."


'/>"/>
Contact: Aditi Risbud
asrisbud@lbl.gov
510-486-4861
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Related biology technology :

1. DOE to Explore Scientific Cloud Computing at Argonne, Lawrence Berkeley National Laboratories
2. Berkeley researchers find new route to nano self-assembly
3. LS9, Inc., U.C Berkeley, and JBEI Make Major Breakthrough in Cellulosic Fuels Production
4. Berkeley researchers take the lead out of piezoelectrics
5. Berkeley Lab scientists create molecular paper
6. Grove Gift Launches Translational Medicine Program at UCSF & UC Berkeley
7. Berkeley Law Survey Challenges Popular Beliefs About Hi-tech Startup Patents
8. Strange new twist: Berkeley researchers discover Möbius symmetry in metamaterials
9. Berkeley Lab scientists control light scattering in graphene
10. Berkeley Lab researchers report tandem catalysis in nanocrystal interfaces
11. Berkeley scientists pioneer nanoscale nuclear materials testing capability
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Shaken, not stirred: Berkeley lab scientists spy molecular maneuvers
(Date:5/18/2017)... ... ... Sherley, was notified earlier this year that his company Asymmetrex had been selected ... Silicon Review , he was not surprised as others might be. Sherley says, “I ... Silicon Valley was particularly meaningful. Our selection by The Silicon Review may ...
(Date:5/16/2017)... , May 16, 2017 Telehealth ... healthcare organizations and something that has been kept ... (EHR) optimization. But according to   Logicalis Healthcare ... an international IT solutions and managed services provider ... and often overlooked – interrelationship between telehealth, imaging, ...
(Date:5/15/2017)... ... May 15, 2017 , ... Algenist is ... Contouring Cream, a gravity-shattering cream with a patented formula, clinically proven to deliver ... the Advanced Lift Contouring Cream to our already innovative ELEVATE product line,” said ...
(Date:5/11/2017)... 2017   BioLife Solutions , Inc. (NASDAQ: ... clinical grade cell and tissue hypothermic storage and ... reported operational highlights and financial results for the first quarter ... reached a new high of $2.4 million in the first ... period in 2016. Revenue growth was driven by sales of ...
Breaking Biology Technology:
(Date:3/24/2017)... -- The Controller General of Immigration from Maldives Mr. ... have received the prestigious international IAIR Award for the most innovative high ... ... Maldives Immigration Controller ... (small picture on the right) have received the IAIR award for the ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and Touchless), ... published by MarketsandMarkets, the market is expected to be worth USD 18.98 billion ... Continue Reading ... ...      (Logo: ...
(Date:3/22/2017)... , March 21, 2017   Neurotechnology , ... recognition technologies, today announced the release of the ... which provides improved facial recognition using up to ... a single computer. The new version uses deep ... accuracy, and it utilizes a Graphing Processing Unit ...
Breaking Biology News(10 mins):