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Separation Systems for Commercial Biotechnology
Date:9/21/2011

NEW YORK, Sept. 21, 2011 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue:

Separation Systems for Commercial Biotechnology

http://www.reportlinker.com/p0619255/Separation-Systems-for-Commercial-Biotechnology.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Biotechnology

THIS REPORT CONTAINS:

* An overview of the U.S. market for separation systems for commercial biotechnology

* Analyses of market trends, with data from 2010, estimates for 2011, and projections of compound annual growth rates (CAGRs) through 2016

* A breakdown of the separation systems for the commercial biotechnology market into major segments of liquid chromatography, centrifugation, membrane filtration, electrophoresis, and niche separations

* Discussion of important technology and the latest advancements in the industry

* Evaluations of important and upcoming patents

* Company profiles of the top players within the industry.

INTRODUCTION

STUDY GOALS AND OBJECTIVES

This market research report provides a comprehensive sizing, analysis, and forecast of the global market for the commercial applications of biotechnology separation systems.

The report will review global markets for biotechnology separation systems and will forecast trends and sales in these markets through 2016. This report provides a range of information, including detailed analyses of the various segments of the market, new applications for separation technology, and overall industry trends. It examines the separation process for a variety of biomolecules, including; proteins, RNA, and DNA. This information will allow the reader to evaluate and quantify the current market size for specific separation systems within the growing biomedical and pharmaceutical technology market.

Forecasts and trends have been developed from a variety of data, including industry sources, company publications, and industry benchmarks. Major separation applications, technologies, geography, and factors influencing the demand for endoscopy services and products will be discussed. Consideration is given to an analysis of government issues versus the biotech and pharmaceutical industry markets.

REASONS FOR DOING THE STUDY

The biomolecule separation market is positioned for significant growth in the next 5 years. This is due to new protein and other biomolecule products that will require separation technology, as well as new innovations in the technology itself. This report investigates one of the major drivers for the separations system market: the development by the biomedical and pharmaceutical industry of proteins that can be used as biotherapeutic agents against a number of human diseases. Another factor that will contribute to growth is the recognition of this technology in emerging markets such as Japan and the Pacific Rim countries. Continued global growth is expected due to a growing middle class in countries such as India, China, Brazil, and Russia.

This report addresses critically important topics for analyzing a changing market dynamic; identifies the emerging players; discusses the technologies and strategies for accessing these emerging markets; and notes the measurement and forecast of specific segments and geographies to allow for enhanced resources allocation.

SCOPE OF REPORT

Current and projected protein and biomolecule separation revenue forecasts during the forecast period (i.e., 2010 to 2016) are discussed. Protein separation systems are playing important roles in new biopharmaceutical development. Protein separation systems do not require U.S. Food and Drug Administration (FDA) approval, but the products produced from these processes do, and they must be produced in accordance with FDA good manufacturing practices (GMP) guidelines. Thus, these separation procedures and equipment must pass FDA audits of the manufacturing process. New products requiring separation technologies that have been approved by the FDA in 2009 and 2010 are covered, and those products expected to be approved within the forecast period are discussed. Due to the timing of the writing of this report, the figures for 2011 are estimated except where actual results have been reported

The report includes analysis of the leading competitors, as well as emerging companies in the current global biomolecule separation market. Profiles of the manufacturers of the leading products are analyzed, and their specific product strategies are outlined. This report notes companies that are poised to introduce new products during the forecast period and discusses how these products may change the face of the competitive environment. This competitive environment is examined, with a special focus on the ways in which developing products and technologies are influencing the current standard of patient care. Detailed profiles of the current market leaders and emerging companies are discussed in detail.

Market figures are based on revenues at the manufacturers' level. The base year for analysis and projection is 2010. Trends are assessed based on a number of parameters, including projected sales for existing products, new product INTRODUCTIONs, and expanded indications for existing products.

This report also includes overviews and forecasts of the separations market by product, by company, and by geographic region for the period from 2010 to 2016. The global market is analyzed, and data are provided for each segment.

Sales figures are reported in U.S. dollars and reflect currency fluctuations within the performance of revenue change. Revenue figures do not account for variation in local currencies.

All market share data are presented on a global basis unless specifically noted.

INTENDED AUDIENCE

This report is an invaluable tool for business planners, acquisitions specialists; licensing strategists; product managers; market research analysts; investors; investor consultants; and anyone interested in the biomolecule separation market, its products, its industry participants, and its future.

It is important to identify overall market trends, product opportunities, emerging geographies, merger and acquisition opportunities, and insights that provide guidance for sales growth and business decisions for a variety of reasons, including:

* Established companies in the industry, including departments that specialize in corporate strategy, sales and marketing, business development, and research and development (R&D), will benefit from the contents of this report.

* Emerging biotechnology players must understand specific opportunities for out-licensing that originates from the differentiation of their products or technologies, as compared with leading, competitive, and emerging technologies. In addition, market forecasts found in this study are supported in detail.

* Investment firms evaluating candidates for venture capital or investment in hedged funds will gain insight into the opportunities and risks that are encountered in the industry with product and company-specific analyses.

* Equity analysts are provided with detailed forecasts for the next 5 years, which are substantiated by quantitative analysis that can support further analysis to product and company forecasts over the short and long run.

METHODOLOGY AND INFORMATION SOURCES

Both primary and secondary research methodologies were used in preparing this report. In-depth interviews were conducted with leading experts in the field, including company executives, industry analysts, and leading biotechnology investigators.

The overall biomolecule separation sector is comprised of a variety of fast–growing, independent segments. For completeness, the current and forecasted markets comprise the total market for each respective segment. Within each sub-section, there is a detailed forecast of each market driver or relevant area of growth.

The information used in preparing this report was obtained from emerging companies in the biomolecule separation industry, including their annual reports, 10Ks, press releases, websites, and other company documents. Information also came from articles published in research journals, such as the Belfort's Biomolecular Separations Research Group, NUS Membrane Research-Bio Separation, Lab-on-a-Chip Technology, Nature Methods, and Trends in Biotechnology. Other information was gathered from the World Health Organization and biotechnology associations. Population estimates are based on those reported by the U.S. Census Bureau's international database. Investigated articles appeared in various journals focusing on biotechnology and bioprocessing.

Current and historical revenue figures for individual products have been acquired from company disclosures that exist in the public domain or from government sources.

CHAPTER ONE: INTRODUCTION . 1

STUDY GOALS AND OBJECTIVES 1

REASONS FOR DOING THE STUDY .. 1

SCOPE OF REPORT 2

INTENDED AUDIENCE .... 3

METHODOLOGY AND INFORMATION SOURCES .... 3

RELATED REPORTS .... 4

BCC ONLINE SERVICES .. 4

DISCLAIMER . 5

CHAPTER TWO: SUMMARY . 6

SUMMARY . 6

SUMMARY TABLE GLOBAL MARKET FOR COMMERCIAL BIOTECH

SEPARATION SYSTEMS BY METHOD OF SEPARATION,

THROUGH 2016 ($ MILLIONS) ... 7

SUMMARY FIGURE GLOBAL MARKET FOR COMMERCIAL

BIOTECH SEPARATION SYSTEMS BY METHOD OF SEPARATION,

2011 AND 2016 ($ MILLIONS) 8

CHAPTER THREE: OVERVIEW 9

BIOMOLECULAR SEPARATION SYSTEMS 9

TABLE 1 GLOBAL MARKET RANKING FOR COMMERCIAL BIOTECH

SEPARATION SYSTEMS, 2011 AND 2016 (%) . 10

RED BIOTECHNOLOGY . 10

WHITE BIOTECHNOLOGY . 10

GREEN BIOTECHNOLOGY 11

BLUE BIOTECHNOLOGY ... 11

ANALYTICAL, PREPARATIVE, AND PRODUCTION SCALE

PROCESSES . 12

ANALYTICAL SCALE SEPARATION PROCESSES . 12

PREPARATIVE SCALE SEPARATIONS 12

PRODUCTION SCALE SEPARATION ... 13

SCOPE 13

BIOMOLECULAR SEPARATIONS AND PURIFICATION .. 14

BIOMOLECULAR SEPARATIONS AND (CONTINUED) ... 15

BIOMOLECULAR SEPARATIONS AND (CONTINUED) ... 16

BIOMOLECULAR SEPARATIONS AND (CONTINUED) ... 17

Biomolecular Separations and Purification (Continued) 18

SEPARATION TECHNOLOGY: CURRENT TRENDS .... 19

SEPARATION TECHNOLOGY . 19

TABLE 2 MAJOR COMPANIES IN THE BIOMOLECULAR

SEPARATION MARKET AND MAJOR PRODUCT AREAS, 2011 . 20

TABLE 2 (CONTINUED) ... 21

DRIVERS AND RESISTORS FOR BIOMOLECULAR SEPARATION

MARKET .. 21

DRIVERS . 21

RESISTORS .. 22

COMMERCIAL BIOMOLECULAR SEPARATION MARKET .. 22

PROTEINS ... 22

Proteins (Continued) .. 23

ANTIBODIES .... 24

ENZYMES .... 25

NUCLEIC ACIDS ... 25

Nucleic Acids (Continued) .... 26

HORMONES 27

CELLS 27

BLOOD AND SERUM PRODUCTS .... 28

ORGANIC PRODUCTS ... 29

TABLE 3 GLOBAL MANUFACTURE OF BULK CHEMICAL

SUBSTANCE BY BIOCATALYSIS, 2010 (METRIC TONS) 29

COMMERCIAL SEPARATION SYSTEMS END-USE MARKETS 30

END USERS OF BIOTECHNOLOGY SEPARATION SYSTEMS . 30

Pharmaceuticals .... 30

Food, Cosmetics, and Agriculture .. 31

Energy 32

COMMERCIAL BIOTECHNOLOGY SEPARATION SYSTEMS ENDUSER

DISTRIBUTION WITHIN THE U.S. MARKET .... 32

BIOTECHNOLOGY ACTIVITY IN THE U.S. ... 32

TABLE 4 DISTRIBUTION OF U.S. BIOTECHNOLOGY AND

BIOPHARMA COMPANIES BY REGION, 2008 (%) .... 33

DISTRIBUTION OF SEPARATIONS SYSTEMS BY END USERS .... 34

DISTRIBUTION OF SEPARATIONS …(CONTINUED) . 35

DISTRIBUTION OF SEPARATIONS …(CONTINUED) . 36

OVERVIEW OF THE GLOBAL COMMERCIAL BIOMOLECULAR

SEPARATIONS MARKET .... 37

TABLE 5 GLOBAL MARKET FOR BIOMOLECULAR SEPARATIONS

SYSTEMS INDUSTRY BY REGION, THROUGH 2016 ($ MILLIONS) .. 37

OVERVIEW OF GLOBAL MARKET SEPARATION SYSTEMS

GROWTH BY SEPARATION METHOD .. 38

TABLE 6 GLOBAL MARKET FOR SEPARATION SYSTEMS BY

SEPARATION METHOD, THROUGH 2016 ($ MILLIONS) . 38

SEPARATION SYSTEMS MARKET: COMPETITIVE STRUCTURE 39

TABLE 7 COMPETITIVE STRUCTURE, 2010 . 39

DISTRIBUTION STRUCTURE . 40

KEY END USERS .. 40

MERGERS AND ACQUISITIONS . 40

TABLE 8 ACQUIRED BIOTECHNOLOGY AND

BIOPHARMACEUTICAL COMPANIES, 2008–2010 ($ MILLIONS) .. 41

TABLE 8 (CONTINUED) ... 42

TABLE 8 (CONTINUED) ... 43

TABLE 8 (CONTINUED) ... 44

TABLE 8 (CONTINUED) ... 45

TABLE 8 (CONTINUED) ... 46

TABLE 8 (CONTINUED) ... 47

TABLE 8 (CONTINUED) ... 47

TABLE 8 (CONTINUED) ... 49

CHAPTER FOUR: CENTRIFUGATION SYSTEMS IN BIOTECHNOLOGY ... 50

CENTRIFUGATION SYSTEMS IN BIOTECHNOLOGY 50

TABLE 9 CENTRIFUGATION PROCESSES AND CHEMICALS USED .... 51

TYPES OF CENTRIFUGATION PROCEDURES .. 51

APPLICATIONS OF CENTRIFUGATION IN SEPARATION ... 52

APPLICATIONS OF CENTRIFUGATION SYSTEMS IN THE

BIOTECH INDUSTRY .... 52

Applications of Centrifugation … (Continued) .. 53

DRIVERS FOR CENTRIFUGATION SYSTEMS IN THE BIOTECH

INDUSTRY ... 54

TABLE 10 GLOBAL MARKET FOR CENTRIFUGATION SEPARATION

SYSTEMS BY REGION, THROUGH 2016 ($ MILLIONS) ... 55

TABLE 11 CENTRIFUGATION SEPARATION SYSTEMS MARKET,

THROUGH 2016 ($ MILLIONS) . 55

DRIVERS FOR CENTRIFUGATION …(CONTINUED) . 56

TABLE 12 PRODUCT TECHNOLOGY IN ULTRACENTRIFUGATION

BY COMPANY, 2011 56

TABLE 12 (CONTINUED) . 57

KEY PLAYERS IN THE CENTRIFUGATION SEPARATION

SYSTEMS GLOBAL MARKET .. 57

CHAPTER FIVE: LIQUID CHROMATOGRAPHY IN BIOMOLECULAR

SEPARATIONS IN BIOTECHNOLOGY .. 58

LIQUID CHROMATOGRAPHY… .. 58

LIQUID CHROMATOGRAPHY…(CONTINUED) . 59

TABLE 13 PRODUCT TECHNOLOGY IN CHROMATOGRAPHY BY

COMPANY, 2011 . 60

TABLE 13 (CONTINUED) . 61

ION EXCHANGE CHROMATOGRAPHY 61

GEL FILTRATION CHROMATOGRAPHY ... 62

AFFINITY CHROMATOGRAPHY . 62

THIN-LAYER CHROMATOGRAPHY . 63

FLASH CHROMATOGRAPHY .. 63

HIGH–PERFORMANCE, THIN-LAYER CHROMATOGRAPHY ... 63

APPLICATIONS OF LIQUID CHROMATOGRAPHY IN THE

GLOBAL BIOMOLECULAR SEPARATIONS INDUSTRY .. 64

LIFE SCIENCES .... 64

PHARMACEUTICAL DEVELOPMENT . 64

CLINICAL .... 65

FOOD AND FLAVOR . 65

DRIVERS OF LIQUID CHROMATOGRAPHY IN THE

BIOMOLECULAR SEPARATION INDUSTRY . 66

MARKET ANALYSIS OF THE GLOBAL LIQUID

CHROMATOGRAPHY BIOTECH INDUSTRY THROUGH 2011 .. 66

TABLE 14 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY

SYSTEMS BY REGION, THROUGH 2016 ($ MILLIONS) ... 67

TABLE 15 GLOBAL MARKET FOR CHROMATOGRAPHY SYSTEMS

BY TECHNOLOGY, THROUGH 2016 ($ MILLIONS) . 67

TABLE 16 KEY PLAYERS IN THE LIQUID CHROMATOGRAPHY

SEPARATION SYSTEMS MARKET, 2010 .... 68

CHAPTER SIX: ELECTROPHORESIS IN BIOMOLECULAR

SEPARATIONS .. 69

TYPES OF ELECTROPHORESIS .. 69

GEL ELECTROPHORESIS .. 69

Two-Dimensional Gel Electrophoresis 70

CAPILLARY ELECTROPHORESIS ... 71

Capillary Gel Electrophoresis ... 72

Capillary Isoelectric Focusing ... 72

Capillary Electro-Chromatography .... 72

DIELECTROPHORESIS . 73

FREE-FLOW ELECTROPHORESIS .. 73

APPLICATION OF ELECTROPHORESIS IN THE BIOMOLECULAR

SEPARATIONS INDUSTRY. 74

DRIVERS OF ELECTROPHORESIS IN THE BIOMOLECULAR

SEPARATIONS INDUSTRY. 75

MARKET ANALYSIS OF GLOBAL ELECTROPHORESIS

BIOMOLECULAR SEPARATIONS .... 75

TABLE 17 GLOBAL MARKET FOR ELECTROPHORESIS SYSTEMS

BY REGION, THROUGH 2016 ($ MILLIONS) 76

TABLE 18 GLOBAL MARKET FOR ELECTROPHORESIS SYSTEMS

BY METHOD, THROUGH 2016 ($ MILLIONS) ... 76

KEY PLAYERS IN ELECTROPHORESIS SEPARATION SYSTEMS

GLOBAL MARKET 77

CHAPTER SEVEN: MEMBRANE FILTRATION IN BIOMOLECULAR

SEPARATIONS .. 78

MATERIAL COMPOSITION OF MEMBRANE FILTERS .... 78

TABLE 19 CLASSES OF FILTRATION BY PORE SIZE AND

APPLICATION .... 78

CROSS-FLOW AND TANGENTIAL FLOW FILTRATION .. 79

BIOMOLECULAR FILTRATION CONFIGURATIONS .. 79

CERAMIC MEMBRANES .... 80

PLASTIC-IRRADIATED-ETCHED FILTERS ... 80

ADVANTAGES OF MEMBRANE SYSTEMS .... 81

DISADVANTAGES OF MEMBRANE SYSTEMS ... 81

APPLICATION OF MEMBRANE FILTRATION TO THE

BIOMOLECULAR SEPARATIONS INDUSTRY .... 81

APPLICATIONS IN THE BIOPHARMA INDUSTRY 82

CURRENT TRENDS ... 82

DRIVERS OF MEMBRANE FILTRATION IN THE BIOMOLECULAR

SEPARATIONS INDUSTRY. 83

HIGH DEMAND FOR PROTEIN SEPARATION .. 83

HIGH QUALITY AND YIELD ... 83

LOW OVERALL COSTS .. 84

MARKET ANALYSIS OF MEMBRANE FILTRATION IN THE

BIOMOLECULAR SEPARATIONS INDUSTRY THROUGH 2016 .... 84

TABLE 20 GLOBAL MARKET FOR MEMBRANE FILTRATION

SYSTEMS BY REGION, THROUGH 2016 ($ MILLIONS) .. 84

KEY PLAYERS IN THE GLOBAL MARKET FOR MEMBRANE

FILTRATION SEPARATION SYSTEMS . 85

KEY PLAYERS IN THE GLOBAL MARKET (CONTINUED) .. 86

CHAPTER EIGHT: NEW METHODS OF BIOMOLECULAR SEPARATION .. 87

MICROARRAY AND LAB-ON-A-CHIP .... 87

MICROARRAYS 87

Microarrays (Continued) . 88

BIOCHIPS .... 89

LAB-ON-A-CHIP .... 90

FLOW CYTOMETRY ... 91

CLINICAL APPLICATIONS OF FLOW CYTOMETER .. 92

MAGNETIC SEPARATION .. 93

MAGNETIC SEPARATION (CONTINUED) 94

TABLE 21 GLOBAL MARKET FOR NEW SEPARATION METHODS BY

REGION, THROUGH 2016 ($ MILLIONS) 95

TABLE 22 MARKET FOR NEW SEPARATIONS METHODS, THROUGH

2016 ($ MILLIONS) . 96

TABLE 23 KEY PLAYERS IN EACH OF THE NEW SEPARATIONS

MARKET SEGMENTS . 97

MAGNETIC SEPARATION (CONTINUED) 98

CHAPTER NINE: COMPANY PROFILES ... 99

AFFYMETRIX .... 99

AGILENT TECHNOLOGIES ... 100

ALFA LAVAL GROUP .... 101

ALFA WASSERMANN SEPARATION TECHNOLOGIES . 102

APPLIED BIOSYSTEMS CORPORATION . 102

BECKMAN COULTER, INC. ... 103

BD BIOSCIENCES (BECTON, DICKINSON, AND COMPANY) . 104

BIO-RAD LABORATORIES, INC. 105

CALIPER LIFE SCIENCES 106

DIONEX . 107

FLOTTWEG SEPARATIONS TECHNOLOGY 108

GE HEALTHCARE LIFE SCIENCES .... 109

HITACHI KOKI CO., LTD. . 109

INVITROGEN .. 110

LIFE TECHNOLOGIES . 111

MILLIPORE BIOMANUFACTURING AND LIFE SCIENCES

(MERCK KGAA) ... 111

NOVASEP LIFE SCIENCES MANUFACTURING SOLUTIONS 112

PALL CORPORATION ... 113

PERKIN-ELMER .. 113

QIAGEN GMBH .... 114

SEPMAG TECHNOLOGIES .... 115

SARTORIUS STEDMAN BIOTECH CORPORATION ... 115

SHIMADZU SCIENTIFIC INSTRUMENTS .... 116

TECAN GROUP, LTD. ... 117

THERMO FISHER SCIENTIFIC . 117

WATERS CORPORATION .. 118

WHATMAN INTERNATIONAL, LTD. ... 119

CHAPTER TEN: PATENTS FOR BIOMOLECULAR SEPARATIONS RELATED

INSTRUMENTATION AND ACCESSORIES ... 120

TABLE 24 PATENTS ISSUED FOR BIOMOLECULAR SEPARATIONS

TECHNOLOGIES, 2005–2010 .. 120

TABLE 25 U.S. AND E.U. BIOMOLECULAR SEPARATIONS PATENTS

BY AREA (%) 121

TABLE 26 BIO-RAD LABORATORIES PARTIAL U.S. PATENT LIST 121

TABLE 26 (CONTINUED) .... 122

TABLE 27 AGILENT TECHNOLOGIES PARTIAL U.S. PATENT LIST ... 122

TABLE 28 GE HEALTHCARE LIFE SCIENCES PARTIAL U.S. PATENT

LIST .... 123

TABLE 29 WATERS CORPORATION PARTIAL U.S. PATENT LIST .. 123

TABLE 30 MERCK MILLIPORE CORPORATION PARTIAL U.S.

PATENT LIST... 124

TABLE 31 GLOBAL CHROMATOGRAPHY PATENTS 124

TABLE 32 MEMBRANE FILTRATION PATENTS ... 126

TABLE 33 ELECTROPHORESIS PATENTS .. 128

APPENDIX .. 129

TABLE 34 KEY WEBSITES 129

TABLE 35 KEY INDUSTRY AND REGULATORY ASSOCIATIONS .... 129

To order this report:

Biotechnology Industry: Separation Systems for Commercial Biotechnology

Biotechnology Business News

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Nicolas Bombourg

Reportlinker

Email: nbo@reportlinker.com

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