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SemBioSys initiates toxicology study for safflower-produced insulin
Date:3/26/2008

that safflower-produced insulin is physically, structurally and physiologically indistinguishable from pharmaceutical-grade human recombinant insulin in laboratory testing. In a standard quantitative blood sugar assay performed in rabbits (insulin tolerance test), SemBioSys has demonstrated the pharmacodynamic equivalence of safflower-produced insulin to pharmaceutical-grade insulin. Thus the completion of this toxicology study fulfills the pre-requisite for filing the IND.

The world market for insulin is US$7.1 billion today and the demand for insulin is projected to increase due to two factors. Demographic and dietary choices in the western world are causing an increase in the incidence of diabetes. At the same time, countries in the rest of the world, that are currently underserved in the insulin market, are demanding greater access to insulin at an affordable price. By 2012, independent estimates predict a US$15 billion insulin market. SemBioSys' plant-made insulin will offer dramatic capital and operating cost reductions with the potential to enter the market as a low-cost source of insulin to meet this exploding demand.

About SemBioSys Genetics Inc. (http://www.sembiosys.com)

Calgary, Alberta-based SemBioSys Genetics Inc. is a biotechnology company developing protein-based pharmaceuticals for metabolic and cardiovascular diseases. The Company's lead pharmaceutical candidates, produced in the plant host safflower, are recombinant human insulin to serve the rapidly expanding global diabetes market and Apo AI, a next generation cardiovascular drug. In addition to its pharmaceutical products, SemBioSys is developing a series of non-pharmaceutical products addressing human topical, nutritional oils and agricultural biotechnology markets.

This press release contains certain forward-looking statements, including, without limitation, statements containing the words "believe", "may", "plan
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SOURCE SemBioSys Genetics Inc.
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