Navigation Links
Selexis SA and the University of Lausanne Announce the Complete Sequencing of the Selexis SURE CHO-M Genome
Date:3/23/2011

eir CMC documentation packages for regulatory filings with the FDA and EMA. In the near future, Selexis will be in a very strong position to utilize the data and genome sequence to engineer new CHO cell lines with defined specificities. More importantly, our engineered CHO cell lines will have enhanced expression capacity, especially for difficult to express recombinant proteins such as blood clot factors or fusion proteins, thus yielding therapeutics of higher quality," said Igor Fisch, CEO, Selexis SA. "The sequencing of our proprietary Selexis SURECHO-M Cell Line was a major accomplishment and a priority for Selexis in the continued improvement of our SURE Technology Platform."

Today, CHO cell lines used in the manufacturing of recombinant biologic therapeutics are from multiple origins and the variations between the CHO genomes are poorly understood. Additionally, the genetic characterization of genetically modified CHO cell lines producing recombinant protein drugs can still be quite challenging, especially when DNA amplification methods have been used to create the cell lines. Thus, regulatory agencies are increasingly looking towards more thorough filing packages. With the improvement of sequencing and genomics technologies, it is now possible to build a genomic map of particular manufacturing cell lines to finely characterize the genetic and production characteristics. Sequencing of the Selexis SURECHO-M Cell Line genome represents one of the first efforts to take genomic scale technology and apply it to industrial biologic manufacturing and regulatory activities.

Selexis and its academic collaborators will continue to work on the data analysis and genome assembly from this work. In addition to allowing more accurate manufacturing of therapeutics, this data will be used to advance the study of gene regulatory networks and expression in the Selexis SURECHO-M Cell Line as well as to improve the quantity and quality of its biologic production ca
'/>"/>

SOURCE Selexis SA
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related biology technology :

1. Selexis SA Doubles Cell Line Development Laboratory Space in Geneva, Switzerland
2. Irvine Scientific and Selexis to Announce Results of Successful Collaboration
3. Selexis Launches Biosimilar Cell Line Development Program
4. China PharmaHub In-Licenses Universal Donor Red Blood Cells Technology Exclusively From University of California, San Diego
5. Mtech Announces Semifinalists for University of Maryland $75K Business Plan Competition
6. University of Maryland School of Medicine publishes scientific paper on 2001 anthrax attacks
7. Queens University professor uses nanotechnology to prolong machine and engine life
8. Binghamton University nanoscientist chosen for the Air Forces Young Investigator Research Program
9. Stemline Therapeutics Licenses Phase I/II Brain Cancer Vaccine - Shows Promise in Clinical Trial Conducted at University of Pittsburgh
10. Georgia Health Sciences University Clinical Study Shows RyMed InVision-Plus® IV Connector Significantly Decreased Central Venous Catheter Occlusions in Oncology Patients
11. Caliper Life Sciences Collaborates with University of Miami to Automate Next Generation Sequencing Workflows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... (PRWEB) May 24, 2013 This ... survey on kinase profiling carried out in May ... of the breakdown of the responses for each ... future (2015). It also highlights some interesting differences, ... groupings. Two bottom-up models were developed to estimate ...
(Date:5/24/2013)... Vestiage, Inc. (stock symbol "VEST") a publicly ... and development, sales and marketing of premium branded ... that it is awarding exclusive Vestiage territories in ... Skin Illuminating Facial Care. Qualified applicants can request ... email to info(at)vestiageinc(dot)com and putting RELUMA in the ...
(Date:5/23/2013)... baby stopped breathing, his collapsed bronchus blocking the crucial ... Gionfriddo watched helplessly, just praying that somehow the dire ... he had a good chance of not leaving the ... son, Kaiba. "At that point, we were desperate. Anything ... with it." , They found hope at the University ...
(Date:5/23/2013)... Baltimore, MD (PRWEB) May 23, 2013 ... time off from work motivate members of the public ... of researchers including Johns Hopkins Carey Business School ... an emphatic yes. Pointing to a large body of ... write in the May 24, 2013, issue of Science ...
Breaking Biology Technology:Kinase Market Profiling - In House & Outsourced Trends 2015 Forecast in New Research Report at ReportsnReports.com 2Kinase Market Profiling - In House & Outsourced Trends 2015 Forecast in New Research Report at ReportsnReports.com 3Kinase Market Profiling - In House & Outsourced Trends 2015 Forecast in New Research Report at ReportsnReports.com 4Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 2Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 3Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 4Vestiage Announces Launch of Exclusive Territories for Reluma Brand Sales in USA 5Baby's life saved with groundbreaking 3-D printed device that restored his breathing 2Baby's life saved with groundbreaking 3-D printed device that restored his breathing 3Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 2Offering Economic Incentives to Attract Blood Donations Should Be Encouraged, Research Team writes in Science 3
... at Rensselaer Polytechnic Institute developed a new method for ... nanomaterial graphene, opening the door to new graphene-based transistors ... humidity, Rensselaer Professor Nikhil Koratkar and his research team ... a critical prerequisite to creating graphene transistors. At ...
... ... ... ... keyed by longUrl, so we need to grab the first one. for (var r in data.results) { first_result = ...
... -- China-Biotics, Inc. ("China-Biotics", the "Company") (Nasdaq: ... probiotics products in China, today announced it will host ... / 9:00 p.m. Beijing Time on Tuesday, November 9, ... and six months financial results for the period ended ...
Cached Biology Technology:Water could hold answer to graphene nanoelectronics 2Water could hold answer to graphene nanoelectronics 3Sirius Genomics Announces Issuance of U.S. Patent 2Sirius Genomics Announces Issuance of U.S. Patent 3Sirius Genomics Announces Issuance of U.S. Patent 4Sirius Genomics Announces Issuance of U.S. Patent 5Sirius Genomics Announces Issuance of U.S. Patent 6Sirius Genomics Announces Issuance of U.S. Patent 7China-Biotics to Report Fiscal Year 2011 Second Quarter Financial Results on November 9 2
(Date:5/24/2013)... Frontiers, one of the world,s largest and fastest growing ... journal, Frontiers in Physics . , A broad ... will provide an open-science and interactive web platform ... rigorously peer-reviewed articles. , Frontiers, real-time and interactive ... range of article types. With an average of three ...
(Date:5/24/2013)... cells spread and grow by avoiding detection and destruction ... can help to eliminate cancer cells; however, there are ... cancer cells. Regulatory T cells are immune cells that ... issue of the Journal of Clinical Investigation , ... that regulatory T cells that infiltrate tumors express proteins ...
(Date:5/24/2013)... After studying noise in one French Quarter neighborhood of ... exceeded municipal ordinances, Annette Hurley, PhD, Assistant Professor of ... Eric Arriaga, a third-year LSUHSC doctor of audiology student, ... own hearing health. Their case study is published online ... Practice Management ., "An important part of an audiologist,s ...
Breaking Biology News(10 mins):Frontiers launches new open-access journal in physics 2Frontiers launches new open-access journal in physics 3Please do try this at home 2
... to New York City from around the world ... Therapy for Cardiovascular Diseases. Dedicated to new advances ... feature an in-depth review of cell-based therapies for ... findings. Highlights include: ...
... the evolutionary mechanisms that facilitate the remarkably fast adaptation ... in the January issue of PLoS Genetics by researchers ... Using germ-free mice a simplified but ecologically relevant ... a model bacterial strain, Escherichia coli MG1655. E. coli ...
... journal Emerging Infectious Diseases, Swedish researchers report that ... with the tundra expedition Beringia 2005, were carriers ... resistance to antibiotics has spread into nature, which ... The scientists took samples from 97 birds ...
Cached Biology News:Cell Therapy for Cardiovascular Diseases 2Cell Therapy for Cardiovascular Diseases 3Dissecting the genetic components of adaptation of E. coli to the mouse gut 2High degree of resistance to antibiotics in Arctic birds 2
The BD OptEIA Rat TNF-alpha ELISA Kit is for the quantitative determination of TNF-alpha in rat serum, plasma and cell culture supernatant....
This SMAD antibody sampler pack contains 5 Polyclonal ,SMAD antibodies....
...
Phosphate-Buffered Saline (PBS) 7.4 (1X) liquid...
Biology Products: