GENEVA, March 23, 2011 /PRNewswire/ -- Selexis SA, a Swiss-based biotechnology company with technologies for the rapid development and engineering of high yield and stable mammalian cell lines for therapeutic protein manufacturing, announced today the Company has completed the sequencing of their proprietary Chinese hamster ovary (CHO) cell line, the Selexis SURECHO-M Cell Line™. The project was performed in collaboration with the Institute of Biotechnology at the University of Lausanne, the SIB Swiss Institute of Bioinformatics and the CHUV, Centre Hospitalier Universitaire Vaudois (Lausanne University Hospital).
CHO cells are the leading industry choice for mammalian production of recombinant biologic therapeutic drugs. Approximately 70% of all recombinant therapeutic proteins and monoclonal antibodies (MAbs) are produced in CHO cells(1). Sales of these drugs exceed $30 billion USD annually. The proprietary Selexis SURECHO-M Cell Line is a high-performance suspension and serum-free adapted CHO cell line derived from the CHO-K1 lineage. The data from the sequencing of the Selexis SURECHO-M Cell Line will be used to generate detailed characterization packages of production clones for filings with regulatory agencies such as the Food and Drug Administration (FDA) and the European Medicines Agency (EMA). Additionally, the data will be used to engineer the cell line's production capabilities in a predictable way.
"The Selexis SURECHO-M Cell Line genome data will be a valuable tool for helping our clients to improve th
|SOURCE Selexis SA|
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