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Selection of Development Candidate Triggers $0.5 Million Milestone Payment to Ardea Biosciences, Inc.
Date:8/19/2007

- Ardea Biosciences Receives Milestone Payment from Valeant Pharmaceuticals

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CARLSBAD, Calif., Aug. 16 /PRNewswire-FirstCall/ -- Ardea Biosciences, Inc. (Pink Sheets: ARDC) today announced that it has received the first milestone payment of $0.5 million from its collaboration partner, Valeant Pharmaceuticals International (NYSE: VRX).

In December 2006, Ardea Biosciences entered into a research collaboration with Valeant Pharmaceuticals International pursuant to which we agreed to collaborate exclusively with Valeant to design a series of compounds to treat neurological disorders.

Valeant's announcement of the selection of several pre-Investigational New Drug (IND) candidates for its next-generation potassium-channel opener program triggered this milestone payment, which recognizes the continuing progress in the identification of novel next-generation compounds to treat serious diseases.

"Starting with a very interesting first generation compound, we have successfully improved its metabolic and pharmacokinetic properties, while increasing potency by up to 50-fold. We are pleased to be recognized for achieving this important milestone and for its validation of our fully-integrated discovery, research and development platform," said Barry D. Quart, PharmD, President and CEO.

About Ardea Biosciences, Inc.

Ardea is focused on the development of small-molecule drugs that address large pharmaceutical markets. We plan to source these development candidates from both our internal drug discovery programs and our continued in-licensing efforts. Our initial therapeutic areas of focus are viral diseases, cancer and inflammatory diseases. We believe that we are
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SOURCE Ardea Biosciences, Inc.

Copyright©2007 PR Newswire.

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