Navigation Links
Seeing the world with new eyes: Biosynthetic corneas restore vision in humans
Date:8/25/2010

A new study from researchers in Canada and Sweden has shown that biosynthetic corneas can help regenerate and repair damaged eye tissue and improve vision in humans. The results, from an early phase clinical trial with 10 patients, are published in the August 25th, 2010 issue of Science Translational Medicine.

"This study is important because it is the first to show that an artificially fabricated cornea can integrate with the human eye and stimulate regeneration," said senior author Dr. May Griffith of the Ottawa Hospital Research Institute, the University of Ottawa and Linkping University. "With further research, this approach could help restore sight to millions of people who are waiting for a donated human cornea for transplantation."

The cornea is a thin transparent layer of collagen and cells that acts as a window into the eyeball. It must be completely transparent to allow the light to enter and it also helps with focus. Globally, diseases that lead to clouding of the cornea represent the most common cause of blindness. More than a decade ago, Dr. Griffith and her colleagues began developing biosynthetic corneas in Ottawa, Canada, using collagen produced in the laboratory and moulded into the shape of a cornea. After extensive laboratory testing, Dr. Griffith began collaborating with Dr. Per Fagerholm, an eye surgeon at Linkping University in Sweden, to provide the first-in-human experience with biosynthetic cornea implantation.

Together, they initiated a clinical trial in 10 Swedish patients with advanced keratoconus or central corneal scarring. Each patient underwent surgery on one eye to remove damaged corneal tissue and replace it with the biosynthetic cornea, made from synthetically cross-linked recombinant human collagen. Over two years of follow-up, the researchers observed that cells and nerves from the patients' own corneas had grown into the implant, resulting in a "regenerated" cornea that resembled normal, h
'/>"/>

Contact: Jennifer Paterson
jpaterson@ohri.ca
613-798-5555 x73325
Ottawa Hospital Research Institute
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Seeing moire in graphene
2. Seeing the quantum in chemistry: JILA scientists control chemical reactions of ultracold molecules
3. bioserie Introduces the Worlds First Made of Plants iPhone 4 Cover
4. Regenicin Completes Acquisition of Worldwide Exclusive Know-How Technology License from Lonza Walkersville
5. The nano world of Shrinky Dinks
6. New Test Centre in India: TUV Rheinland Continues Worldwide Investment Programme for Solar Industry
7. New Advances in Understanding of Parasite Risk Showcased at CVBD World Forum
8. Engineering researchers simplify process to make worlds tiniest wires
9. United Nations' World Population Day Calls Attention to Key Global Issues
10. Aeterna Zentaris: Perifosine Data Selected for Oral Presentation at Upcoming 12th World Congress on Gastrointestinal Cancer
11. Progenika Biopharma Grants Grifols World-Wide Distribution Rights for the BLOODCHIP® Genotyping Test for Blood Donors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Seeing the world with new eyes: Biosynthetic corneas restore vision in humans
(Date:12/22/2014)... Dec. 22, 2014  ( www.competitivehealth.com ) — Competitive ... medical bill review and advocacy service, has signed an ... WellCard Savings discount health services marketplace. 63% ... more than they expected to pay. As part of ... costs, WellCard Savings is pleased to offer medical bill ...
(Date:12/22/2014)... 22, 2014 Fertility Associates of Memphis ... Bank USA , a network of more than 20 ... partnership, patients have fast access to a national pool ... IVF . Fertility Associates of Memphis is the only ... treatment option. , Dr. William Kutteh , director ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one ... of Nick Maroulis, Pharm.D. to the newly created position ... In this position, Dr. Maroulis will continue to manage ... of our multi-site pharmacies as the company expands. Dr. ... that time he has served in many different capacities ...
(Date:12/19/2014)... Dec. 19, 2014 Bina Technologies, Inc. (Bina, ... that they have been acquired by Roche (SIX: RO, ... privately held company that provides a big data platform ... (NGS) data for the academic and translational research markets. ... and will continue to focus on development of their ...
Breaking Biology Technology:WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... 4, 2011 Radient Pharmaceuticals Corporation (OTCQX:RXPC) (OTCPK:RXPC), a ... (IVD) cancer tests, today announced that all six proxy ... The Company,s proxy statement was filed with ... is available at www.sec.gov and on the ...
... N.C., Nov. 4, 2011 NeuroCog Trials, Inc. today ... the position of Chief Operating Officer.  In this newly ... continued growth and expansion of NeuroCog Trials, business, research ... research and development for pro-cognitive therapies across a wide ...
... 4, 2011 Major milestone achieved in ... of patients with refractory ascites due to liver cirrhosis. ... and Vienna General Hospital (AKH Wien) reported that the ... were performed at Vienna General Hospital in October, under ...
Cached Biology Technology:Radient Pharmaceuticals Announces Proxy Resolutions Approved at Special Meeting of Stockholders 2NeuroCog Trials Appoints Industry Executive Michael Hufford, Ph.D. to Chief Operating Officer 2The Medical University of Vienna and Vienna General Hospital Perform the First two Commercial Implants Worldwide of Sequana Medical's ALFApump® System 2
(Date:12/3/2014)... , Dec. 2, 2014   Marvin Test ... innovative test solutions for military, aerospace, and manufacturing ... of its successful TS-900 PXI semiconductor test ... features of high-end systems to customers at a ... compared to traditional ATE. "Our ...
(Date:11/21/2014)... -- Earlier this year Donald Spector , Chairman of ... the most prolific inventors in the world, got a ... to third party agencies. Spector envisioned this technology even ... earliest known patents in this area. Now major technology ... care, elder care and hospital applications. This technology has ...
(Date:11/21/2014)... JOSE, Calif. , Nov. 20, 2014   ... global leader in microcontroller (MCU) and touch technology solutions, ... digital temperature sensors with the widest V cc ... delivers higher temperature accuracy and faster I 2 C ... registers and serial EEPROM memory making them ideal for ...
Breaking Biology News(10 mins):Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4
... Engineering established to be a world leading centre in ... Excellence (RCE) supported by NRF and MOE, bringing the ... 2007 , , 1. The National Research Foundation (NRF) and ... support for a Research Centre of Excellence (RCE) called ...
... of reports, the ACSS has collected a number of stories ... that will improve everyone,s wellbeing. The impact of social science ... re-employment to healthy diets and the wellbeing of children. ... will present her research on the value of fathers and ...
... 10, 2010) The American Psychiatric Association today released ... of Diagnostic and Statistical Manual of Mental Disorders (DSM). ... consideration for DSM, which is the standard classification of ... professionals, and is used for diagnostic and research purposes. ...
Cached Biology News:NTU sets up centre on micro-organism research for environmental engineering and sustainability 2NTU sets up centre on micro-organism research for environmental engineering and sustainability 3NTU sets up centre on micro-organism research for environmental engineering and sustainability 4APA announces draft diagnostic criteria for DSM-5 2APA announces draft diagnostic criteria for DSM-5 3APA announces draft diagnostic criteria for DSM-5 4APA announces draft diagnostic criteria for DSM-5 5
... The lyophilization stabilizer is designed ... process and for long-term storage. ... toxic ingredients. It is a ... pH 7.2, and is superior to ...
... coating stabilizer is designed for stabilizing ... and antibodies for immunoassay development. ... during the coating and drying process ... It can also works as a ...
... Clinical is Tecans open platform for clinical ... safety and performance in the clinical diagnostic ... by flexible barcode reading and sample traceability ... the system complies with the IVD-Directive* established ...
... the smallest thermal cyclers on the market, which ... 0.5ml (20 samples) or 0.2ml microtube (25 samples) ... and cooling rate of 3.6C/sec and 2.0C/sec respectively ... Fast track programming with new quick dial facility ...
Biology Products: