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Seaside publishes research supporting disease-modifying potential of STX209 for fragile X syndrome
Date:9/19/2012

of FXS. Post-hoc analysis of ABC-Social Avoidance scale, a newly validated scale for the assessment of FXS, revealed a significant beneficial treatment effect in the full study population (p<0.01). A post-hoc subgroup of 27 subjects with more severe social impairment showed improvements on the Vineland II-Socialization raw score (p=0.03), the ABC-Social Avoidance scale (p=0.04) and on all global measures. The results suggest that STX209 has the potential to improve social function and behavior in patients with FXS.

Study authors included Elizabeth M. Berry-Kravis of Rush University Medical Center, Randi J. Hagerman, David R. Hessl, Yi Mu and Danh V. Nguyen of the University of California Davis; Barbara Rathmell, Peter Zarevics, Maryann Cherubini, Karen Walton-Bowen, Paul P. Wang and Randall L. Carpenter of Seaside Therapeutics; Joseph Gonzalez-Heydrich of Children's Hospital Boston; and Mark F. Bear of the Massachusetts Institute of Technology.


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Contact: Kari Watson
kwatson@macbiocom.com
781-235-3060
MacDougall Biomedical Communications, Inc.
Source:Eurekalert

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