Navigation Links
Scientists synthesize memory in yeast cells
Date:9/22/2007

BOSTON, Mass. (September 14, 2007)Harvard Medical School researchers have successfully synthesized a DNA-based memory loop in yeast cells, findings that mark a significant step forward in the emerging field of synthetic biology.

After constructing genes from random bits of DNA, researchers in the lab of Professor Pamela Silver, a faculty member in Harvard Medical Schools Department of Systems Biology, not only reconstructed the dynamics of memory, but also created a mathematical model that predicted how such a memory device might work.

Synthetic biology is an incredibly exciting field, with more possibilities than many of us can imagine, says Silver, lead author of the paper to be published in the September 15 issue of the journal Genes and Development. While this proof-of-concept experiment is simply one step forward, weve established a foundational technology that just might set the standard of what we should expect in subsequent work.

Like many emerging fields, theres still a bit of uncertainty over what, exactly, synthetic biology is. Ask any three scientists for a definition, and youll probably get four answers.

Some see it as a means to boost the production of biotech products, such as proteins for pharmaceutical uses or other kinds of molecules for, say, environmental clean-up. Others see it as a means to creating computer platforms that may bypass many of the onerous stages of clinical trials. In such a scenario, a scientist would type the chemical structure of a drug candidate into a computer, and a program containing models of cellular metabolism could generate information on how people would react to that compound.

Either way, at its core, synthetic biology boils down to gleaning insights into how biological systems work by reconstructing them. If you can build it, it forces you to understand it.

A team in Silvers Harvard Medical School lab led by Caroline Ajo-Franklin, now at Lawrence Ber
'/>"/>

Contact: David Cameron
public_affairs@hms.harvard.edu
617-432-0442
Harvard Medical School
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. UW computer scientists fighting computer virus "Cold War"
2. Scientists find way to make human collagen in lab
3. Wisconsin scientists to be recognized for innovative biofuel technology
4. UW-Madison scientists to mimic nature for newest cancer drugs
5. UW scientists study strange material with communications potential
6. Scientists find nanotech method for examining cells
7. UW space scientists use Keck telescope to study wild weather of Uranus
8. UW computer scientists tout achievements and explain industry shortcomings
9. Facing shortage of U.S. scientists, UW wants to boost math enrollment
10. UW-Madison scientists find a key to cell division
11. TIP/UW Scientists Provide Mars Rover Commentary
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2015)... April 28, 2015 IMS is ... bring it to the web and provide greater ... user friendly reporting metrics increase data warehouse’s utility; ... convenient recall and access “on-the-go” makes data analysis ... using client feedback to assist in repository analytics ...
(Date:4/28/2015)... Reproductive endocrinologist Dr. Kaylen Silverberg , ... battling infertility in this country, testified on behalf of ... first state in the nation to consider creating a clearinghouse ... who desire to receive them. , Infertility affects over 7.3 ... is one of the few medical diseases that is curable, ...
(Date:4/27/2015)... 27, 2015 Dr. Robert Hanzlik, whose ... toxicity carries implications for advancing the creation of safer ... National University , the second-largest private, nonprofit university ... Hanzlik, a professor at the University of Kansas School ... design, starts at 5 p.m. and takes place at ...
(Date:4/27/2015)... Kan. , April 27, 2015   ... a pet therapeutics company focused on the licensing, ... companion animals, today provided commentary on clinical study ... during a poster session at the American Association ... ADXS31-164 is a novel Lm -LLO ...
Breaking Biology Technology:Texas Fertility Center Supports a Groundbreaking HB1145 that Facilitates Embryo Donation in Texas 2Texas Fertility Center Supports a Groundbreaking HB1145 that Facilitates Embryo Donation in Texas 3Dr. Robert Hanzlik Discusses Pharmaceutical Testing Models at Event Hosted by National University 2Dr. Robert Hanzlik Discusses Pharmaceutical Testing Models at Event Hosted by National University 3Aratana Therapeutics Comments on ADXS31-164 (AT-014) Study Data Presented During Poster Session at the American Association for Cancer Research (AACR) Annual Meeting 2015 2
... grow by over ... 100%, year-over-year, ... ATSI ), manufacturer and marketer of state-of-the-art cardiac,surgery products and ... 2008., (Logo: http://www.newscom.com/cgi-bin/prnh/20040202/ATSILOGO ), The Company currently ...
... National Institute of Standards and Technology (NIST) and the ... a rare-earth element, erbium, to within two millionths of ... and laser cooling technique. Their recent report* is a ... manipulate individual atoms of erbium, an element with unique ...
... SAN FRANCISCO, Calif., April 2, 2008 ... development of novel,pharmaceutical therapies for the treatment ... the U.S. Food and Drug Administration,(FDA) has ... selective,blocker of proteasome activity for the treatment ...
Cached Biology Technology:ATS Medical Expects First Quarter Revenue of $14.6 to $14.8 Million 2ATS Medical Expects First Quarter Revenue of $14.6 to $14.8 Million 3Bon MOT: Innovative atom trap catches highly magnetic atoms 2Proteolix's Carfilzomib Receives Orphan Drug Designation for Treatment of Multiple Myeloma 2Proteolix's Carfilzomib Receives Orphan Drug Designation for Treatment of Multiple Myeloma 3
(Date:4/13/2015)... 13, 2015 According to ... Biometrics Market Forecast & Opportunities, 2020", the global biometrics ... around 14% till 2020. The biometrics market is ... implementation and review of biometric management systems. The ... products with greater efficiency, are resulting in increasing ...
(Date:4/9/2015)... Calif. , April 9, 2015 Synaptics ... interface solutions, announced today that it will report financial ... Thursday, April 23, 2015, after the close of market. ... analysts and investors at 2:00 p.m. PT (5:00 p.m. ... To participate on the live call, analysts ...
(Date:4/2/2015)... Germany , April 2, 2015 ... fingerprint tests DERMALOG by far outperforms the strongest ... always maintaining high accuracy, the system is capable ... Hence, the speed proves up to be ten ... faster than its runner-up performance.      ...
Breaking Biology News(10 mins):Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2Synaptics to Report Third Quarter Results on April 23 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3
... Salk Institute for Biological Studies and Iowa State University ... role in the production of seed oils, substances important ... Scoring a rare scientific hat trick, the researchers ... ( Arabidopsis thaliana ) that regulate the metabolism of ...
... of the University,s Faculty of Biological Sciences are working with ... of molecular signatures that will help identify the severity of ... team is barcoding different strains of influenza virus and human ... onset of asthma in young children. "Diseases such as ...
... China BGI, the world,s largest genomics organization, in ... the genome sequence and analysis of foxtail millet ( ... millet. This study provides an invaluable resource for the ... crops at a genome-wide level. Results of the latest ...
Cached Biology News:Discovery of plant proteins may boost agricultural yields and biofuel production 2Discovery of plant proteins may boost agricultural yields and biofuel production 3Virus 'barcodes' offer rapid detection of mutated strains 2BGI reports the completed sequence of foxtail millet genome 2
... output accessory lessens the expensive task ... laboratories with multiple mass spectrometers. It ... from Agilent 1100 Series LC/MSD quadrupole ... transmits the analog data directly to ...
... SOS Protein Solubility Service, We ... , New SOS technology yields the best ... parameters applied on each clone submitted , ... ,The new protein Solubility Optimization Service ...
... were designed for full-length gene cloning and ... identify the desired cDNA clone. The first ... "Master Plate," where each well contains plasmid ... positive well(s) by gel electrophoresis of the ...
... were designed for full-length gene cloning and ... identify the desired cDNA clone. The first ... "Master Plate," where each well contains plasmid ... positive well(s) by gel electrophoresis of the ...
Biology Products: