Navigation Links
Scientists reveal how biological activity is regulated in fruit fly and roundworm genomes
Date:12/22/2010

Scientists today published catalogs of the fruit fly and roundworm's functional genomic elements: DNA sequences in the genome that carry the instructions and determine which genes are turned on and off at various times in different cells.

Initially sequenced as part of the Human Genome Project, the genomes of the fruit fly, Drosophila melanogaster, and the roundworm, Caenorhabditis elegans, are powerful models for understanding human biology and disease, as many functional genomic elements have been conserved across the vast evolutionary distances separating each organism. Scientists can now study functional genomic elements in the fruit fly and roundworm that are also present in humans to better understand how the human genome works in health and disease.

"These findings will enable scientists everywhere to carry out experiments in fruit flies and roundworms to better understand the relationship between molecular and biological activities in these animals," said NHGRI Director Eric D. Green, M.D., Ph.D. "What we learn from these model organisms will contribute greatly to our understanding about the genomic basis of health and disease in humans."

The papers reporting these new findings will appear in the Dec. 24 issue of Science and are authored by members of the model organism ENCyclopedia Of DNA Elements (modENCODE) Consortium, which is funded by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH). In addition, more than a dozen companion modENCODE papers will be published online in the journals Nature, Genome Research and Genome Biology.

The fruit fly and roundworm modENCODE projects were launched in 2007 to complement the work being done by the ENCyclopedia Of DNA Elements Consortium (ENCODE) Project, which is building a comprehensive catalog of functional genomic elements in the human genome. In 2007, ENCODE completed a pi
'/>"/>

Contact: Geoff Spencer
spencerg@mail.nih.gov
301-402-0911
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4

Related biology technology :

1. Clemson scientists put a (nano) spring in their step
2. City of Hope Helps KGI Launch New Management Training Program for Scientists
3. University of Pennsylvania scientists move optical computing closer to reality
4. Scientists grow nanonets able to snare added energy transfer
5. The National Cancer Institute Joins the Global Community of Scientists Now Using BIOMARKERcenter From Thomson Reuters
6. Scientists peel away the mystery behind golds catalytic prowess
7. SACHEM Launches 2-D HPLC e-Learning Program : New e-Learning Program Teaches Scientists How to Better Analyze and Prove Product Purity Through Greater Sensitivity and Precision in Identification of Trace Components
8. Vermillion and Stanford Scientists Receive Best Research Award From the PAD Coalition
9. Brewing better beer: Scientists determine the genomic origins of lager yeasts
10. Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation
11. CU scientists create worlds thinnest balloon -- just one atom thick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Jan. 22, 2015  Transwestern | RBJ today announces the firm ... space for Shire a leading biopharmaceutical company, at Two Ledgemont ... RBJ,s Robert Richards , president, and Brian Cohen ... the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... Pipette.com has added the Eppendorf ... portfolio of Eppendorf products. , The Eppendorf Centrifuge 5424/5424 ... 5424/5424 R and receive the following:, , ... or Eppendorf Reference 2 ,     3 Free ...
(Date:1/22/2015)... January 22, 2015 Diagenode, Inc., ... as the Bioruptor® and complete solutions for epigenetics ... chromatin immunoprecipitation, alleviating the need for manual processing. ... needed for ChIP of histones or transcription factors ...
(Date:1/22/2015)... N.J. , Jan. 22, 2015  Derma Sciences, ... regeneration company focused on advanced wound care, announces ... placental tissues, have been added to the Premier, ... increases the opportunity for the AMNIOEXCEL® and AMNIOMATRIX® ...
Breaking Biology Technology:Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5
... 17, 2011 Hadasit Bio-Holdings, Ltd. - (OTCBB: HADSY), ... on intellectual property developed by the Hadassah University Hospital, ... company Enlivex Therapeutics (92% owned by Hadasit Bio) has ... in its Phase I / II clinical trial using ...
... ReportsnReports   announces ... Recovery Solutions, Electric Vehicle, Telemedicine, NFC PoS Terminal, 3D ... Technoavio / Infiniti Research has recently ... Priced differently based on the market and geography researched, ...
... Institute for Biotechnology) and Ghent University have shown that ... rheumatoid arthritis, an often-crippling inflammation of the joints that ... the underlying molecular mechanism of the disease was largely ... , the researchers demonstrate that a cell-specific defect in ...
Cached Biology Technology:Clinical Developments at Enlivex Therapeutics - a Hadasit Bio-Holdings Portfolio Company 2Clinical Developments at Enlivex Therapeutics - a Hadasit Bio-Holdings Portfolio Company 3Clinical Developments at Enlivex Therapeutics - a Hadasit Bio-Holdings Portfolio Company 4ReportsnReports - Global Hospital Information Systems, Mobile Health Applications, Electric Vehicle Market Research Reports 2ReportsnReports - Global Hospital Information Systems, Mobile Health Applications, Electric Vehicle Market Research Reports 3ReportsnReports - Global Hospital Information Systems, Mobile Health Applications, Electric Vehicle Market Research Reports 4ReportsnReports - Global Hospital Information Systems, Mobile Health Applications, Electric Vehicle Market Research Reports 5Defect in A20 gene expression causes rheumatoid arthritis 2
(Date:12/22/2014)... Conn. , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce market, ... Apollo Robbins for the 2015 International CES debut ... Apollo Robbins will be at the NXT-ID booth January ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... "Micro Market Monitor: North America Perimeter Security Systems Market" ... The North American perimeter security market is ... to 2019. Although the U.S. market holds a larger share ...
(Date:12/17/2014)... , Dec. 15, 2014 The Defense Logistics Agency ... detect and prevent counterfeit microcircuits from entering into its ... an in-house microcircuit anti-counterfeit initiative dubbed DNA marking. The ... increasing their reliability throughout the supply chain. The new ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
... other medicines inside soil microbes and other natural sources is ... than 50 percent of today,s prescription drugs. This new era ... Chemical & Engineering News , the weekly newsmagazine of ... editor, points out that natural products are the source of ...
... genomes provide useful medical information beyond what current newborn ... question are being funded by the Eunice Kennedy Shriver ... and the National Human Genome Research Institute (NHGRI), both ... $5 million to four grantees have been made in ...
... controlled study of science faculty at minority-serving institutions ... increased the number of peer-reviewed research publications, the ... professional and curricular activities of those who participated ... The study, published today in the journal, ...
Cached Biology News:NIH program explores the use of genomic sequencing in newborn healthcare 2NIH program explores the use of genomic sequencing in newborn healthcare 3NIH program explores the use of genomic sequencing in newborn healthcare 4Outside mentoring support for science faculty at minority-serving institutions pays off 2Outside mentoring support for science faculty at minority-serving institutions pays off 3Outside mentoring support for science faculty at minority-serving institutions pays off 4
... 'Agilents GeneSpring Workgroup solution is ... managing and mining expression data in ... and is deployed in over 40 ... research organizations worldwide. GeneSpring Workgroup streamlines ...
... Western blotting is a commonly used ... Typically, protein samples are electrophoresed on SDS-PAGE ... nitrocellulose or nylon, where they are probed ... technologies, which allow reuse of Southern and ...
... microarrays designed for quantitative assays using ... built on the flexible and powerful ... customer specified sequences can be synthesized ... assistance with custom sequence design. These ...
... Chemicon Select Tissue Arrays are intended for ... tissues were fixed in neutral buffered formalin ... and diagnosis was performed by certified pathologists. ... paraffin blocks and relocated into a new ...
Biology Products: