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Scientists develop way to successfully give nanoparticle therapeutics orally
Date:11/27/2013

be used to carry any kind of drug to treat many diseases.

"Being able to deliver nanomedicine orally would offer clinicians broad and novel ways to treat today's many chronic diseases that require daily therapy, such as diabetes and cancer," said Langer. "Imagine being able to take RNA or proteins orally; that would be paradigm shift."

In terms of next steps, the researchers are working to enhance the nanoparticles' drug-releasing abilities to prepare for future pre-clinical testing with insulin and other drugs. They also plan to design nanoparticles that can cross other barriers, such as the blood-brain barrier, which prevents many drugs from reaching the brain.

"If you can penetrate the mucosa in the intestine, maybe next you can penetrate the mucosa in the lungs, maybe the blood-brain barrier, maybe the placental barrier," said Farokhzad.


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Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-525-6383
Brigham and Women's Hospital
Source:Eurekalert

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