Navigation Links
Scientists 'boot up' a bacterial cell with a synthetic genome
Date:5/20/2010

Scientists have developed the first cell controlled by a synthetic genome. They now hope to use this method to probe the basic machinery of life and to engineer bacteria specially designed to solve environmental or energy problems.

The study will be published online by the journal Science, at the Science Express website, on Thursday, 20 May. Science is published by AAAS, the nonprofit science society.

The research team, led by Craig Venter of the J. Craig Venter Institute, has already chemically synthesized a bacterial genome, and it has transplanted the genome of one bacterium to another. Now, the scientists have put both methods together, to create what they call a "synthetic cell," although only its genome is synthetic.

"This is the first synthetic cell that's been made, and we call it synthetic because the cell is totally derived from a synthetic chromosome, made with four bottles of chemicals on a chemical synthesizer, starting with information in a computer," said Venter.

"This becomes a very powerful tool for trying to design what we want biology to do. We have a wide range of applications [in mind]," he said.

For example, the researchers are planning to design algae that can capture carbon dioxide and make new hydrocarbons that could go into refineries. They are also working on ways to speed up vaccine production. Making new chemicals or food ingredients and cleaning up water are other possible benefits, according to Venter.

In the Science study, the researchers synthesized the genome of the bacterium M. mycoides and added DNA sequences that "watermark" the genome to distinguish it from a natural one.

Because current machines can only assemble relatively short strings of DNA letters at a time, the researchers inserted the shorter sequences into yeast, whose DNA-repair enzymes linked the strings together. They then transferred the medium-sized st
'/>"/>

Contact: Natasha Pinol
npinol@aaas.org
202-326-7088
American Association for the Advancement of Science
Source:Eurekalert  

0

GOOD

Page: 1 2

Related biology technology :

1. Scientists ID bacterial genes that improve plant growth
2. Nano parfait a treat for scientists
3. Berkeley Lab scientists create molecular paper
4. Brown University scientists discover new principle in material science
5. NIST scientists address wrinkles in transparent film development
6. Scientists discover worlds smallest superconductor
7. Carnegie Mellon scientists create rainbow of fluorescent probes
8. MIT scientists transform polyethylene into a heat-conducting material
9. Scientists discover how ocean bacterium turns carbon into fuel
10. Scientists glimpse nanobubbles on super nonstick surfaces
11. Princeton scientists find an equation for materials innovation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Scientists 'boot up' a bacterial cell with a synthetic genome
(Date:5/24/2013)... and TEL AVIV, Israel , ... or the "Company") (NYSE MKT: NSPR), a leader in embolic ... the Company,s President and Chief Executive Officer, and ... participate in the Benchmark Company, LLC One-on-One Investor Conference on ... Wisconsin Ave., Milwaukee, WI. ...
(Date:5/24/2013)... 2013 This market report summarizes ... profiling carried out in May 2013. The full ... of the responses for each question, its segmentation ... also highlights some interesting differences, particularly between Pharma, ... models were developed to estimate the in house ...
(Date:5/24/2013)... The Oklahoma tornado left the ... the mayor of Moore, one of the heavily damaged towns, ... report from cnn.com. Reaching out to also be of help, ... Safe Shield to counter the looming mold problem. , The ... 22, 2013, caused 24 deaths, My Cleaning Products shared. Ten ...
(Date:5/24/2013)... 2013 Quincy Bioscience, a leading ... of calcium-binding proteins to support healthy living, is ... study of apoaequorin in Food and ... the British Industrial Biological Research Association. , ... potential adverse effects, if any, of apoaequorin, in ...
Breaking Biology Technology:InspireMD To Participate In Benchmark Investor Conference On May 30th 2InspireMD To Participate In Benchmark Investor Conference On May 30th 3InspireMD To Participate In Benchmark Investor Conference On May 30th 4Kinase Market Profiling - In House & Outsourced Trends 2015 Forecast in New Research Report at ReportsnReports.com 2Kinase Market Profiling - In House & Outsourced Trends 2015 Forecast in New Research Report at ReportsnReports.com 3Kinase Market Profiling - In House & Outsourced Trends 2015 Forecast in New Research Report at ReportsnReports.com 4Mayor of Oklahoma-Tornado-Impaired Town Proposes Storm Shelter Bill, My Cleaning Products Offers Complimentary Molderizer and Safe Shield to Help Victim with Looming Mold 2Safety Assessment Study of Apoaequorin Published in Food and Chemical Toxicology 2
... , New BL21-Gold cells accelerate the protein ... Jerpseth Lisa Breister Alan,Greener ,Stratagene , ... the new BL21-Gold,series. Epicurian Coli ... the EndA1 nuclease and offer 100-fold higher,transformation efficiencies ...
... Monitor activation status of interferon-stimulated signaling pathways , ... Buchanan Chao-Feng Zheng ,Stratagene , Stratagenes family of ... ISRE reporting systems, to better study the,activation of signal ... b , or - g . The ...
... in any tissue with the Big Blue ... Barry W. Glickman ,Centre for Environmental Health, University ... Blue transgenic rodent mutation,assay,* which carries ... shuttle vector, it is easy to study mutations in ...
Cached Biology Technology:High-efficiency Derivatives of the BL21 Series for Protein Expression 2High-efficiency Derivatives of the BL21 Series for Protein Expression 3New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 2New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 3New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 4New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 5New Reporter Plasmids for Studying Interferon-Stimulated Signal Transduction,Pathways 6Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer 2Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer 3Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer 4Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer 5Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer 6Tissue Specificity for Mutation Parallels Tissue Specificity for Cancer 7
(Date:5/24/2013)... leading water scientists from around the world today issued ... short span of one or two generations, the majority ... living under the handicap of severe pressure on fresh ... is no substitute. This handicap will be self-inflicted and ... pointed to chronic underlying problems led by mismanagement and ...
(Date:5/23/2013)... year, carrying more than 284 million tons of cargo, transit ... in toll fees for the Panama Canal Authority. Each time ... water are used from Gatun Lake, which is also a ... the isthmus. , However, the advent of very large ... ships at sea, has demanded change. The Panama Canal is ...
(Date:5/23/2013)... implications for the overall health, development, and academic ... role in ensuring that all students have opportunities ... day of vigorous or moderate-intensity physical activity, says ... Recent estimates suggest that only about half ... promoting better health and development. The report ...
Breaking Biology News(10 mins):A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 2A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 3A majority on Earth face severe self-inflicted water woes within 2 generations: Scientists 4Reforestation study shows trade-offs between water, carbon and timber 2Reforestation study shows trade-offs between water, carbon and timber 3Schools should provide opportunities for 60 minutes of daily physical activity to all students 2Schools should provide opportunities for 60 minutes of daily physical activity to all students 3
... position to monitor environmental conditions in remote areas of the ... scientists believe the cultural and educational gulf between trained scientists ... that native peoples cannot be relied on to collect reliable ... Jose Fragoso have completed a five-year environmental study of a ...
... This release is available in French . ... have received new funding to advance research in fields ranging ... committee, Canada Research Chairs were awarded to the following professors ... announcement was made at Concordia in the presence of Senator ...
... A University of Minnesota team of researchers has overcome ... specialized type of molecular sieve that could make the ... effective and energy efficient. The breakthrough research, led by ... the university,s College of Science and Engineering, is published ...
Cached Biology News:Can indigenous peoples be relied on to gather reliable environmental data? 2Can indigenous peoples be relied on to gather reliable environmental data? 3Recognition for 7 Concordia professors 2Minnesota discovery could make fuel and plastics production more energy efficient and cost effective 2
... the needs of the biopharmaceutical ... supports fast cell growth rates ... maintaining high cell viability and ... the Baculovirus Expression Vector System ...
... number is a new ... easily match Cornings product ... availability yet, please order ... number (Z36,327-8) or contact ...
Originally developed for the culture of Drosophila; suitable for culture of other dipteran cell lines. Powder, Insect cell culture tested...
... This CLS number is ... to easily match Cornings product ... yet, please order under the ... contact customer service for assistance. ...
Biology Products: