Navigation Links
Sarcoma Alliance Excited About New Drug Research
Date:6/25/2013

h-grade soft-tissue sarcomas for which doxorubicin is an appropriate front-line regimen.

Some critics have suggested that clinical trials be limited to only the sarcoma subtypes that show the greatest initial response. But Dr. Tap said he wouldn’t want to focus on one or two subtypes while other patients who might have responded go untested.

"A phase 2 study showed broad activity across sarcoma subtypes."

Some recent drug studies have looked at progression-free survival, i.e., how long a patient lives without the sarcoma returning or advancing. The TH-302 trial looks at whether patients live longer, Dr. Tap said.

“In sarcoma, in more than 30 years, we haven't had a new drug that we believe affects overall survival," he said, except those used for gastrointestinal stromal tumors.

Some people think TH-302 may fail because palifosfamide did, Beckert said. Both are chemical cousins of ifosfamide, but less toxic. Ifosfamide, an older drug, is sometimes paired with doxorubicin for chemotherapy. The palifosfamide trial combined it with doxorubicin in one arm vs. doxorubicin alone – similar to the TH-302 trial.

"They're different drugs,” Dr. Tap said. “It's like comparing apples and oranges. The key is the delivery method."

Unlike palifosfamide, TH-302 activates in tissue with low oxygen, and those conditions often exist in the center of a sarcoma, he said. This differs from other drugs that attack the edges of tumors, which have more blood vessels and thus, more oxygen.

For more information on the Sarcoma Alliance, go to http://sarcomaalliance.org

Read the full story at http://www.prweb.com/releases/2013/6/prweb10866921.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools
2. Edison Expands French Healthcare Sector Coverage With Initiation of Coverage on BioAlliance Pharma
3. Smart Consulting Group and The Catalyst Group Form Alliance to Supply Quality Compliance Consulting Services For the Pharmaceutical Industry
4. VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials
5. Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC
6. The Alliance for the Advancement of Adult Stem Cell Therapy and Research Recently Has Proven Stem Cells To Be Effective in Dilated Cardiomyopathy
7. Emergent Technologies and Caisson Biotech Form Strategic Alliance with Local Health Care Providers to Improve Delivery and Performance of a Therapeutic Drug
8. ClearPath Workforce Management CEO Appointed Co-chair of Northern California Leadership Forum for Woman Owned Business Alliance
9. Campbell Alliance to Release New Forward-Looking Industry Report on Deal-Making Trends at the 2013 BIO International Convention
10. SoundConnect Announces New Not-For-Profit Customer in Smart Card Alliance
11. Alliance to Feed the Future Congratulates Our Farmers, Supports Education for Future Generations on National Agriculture Day
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... University of Minnesota electrical engineering researchers have developed ... time demonstrates mechanical transportation of light. The discovery ... more efficient optical devices for computation and communication. ... electrical and computer engineering assistant professor Mo Li ... published online and will appear in the October ...
(Date:9/22/2014)... Lawrence Livermore National Laboratory Director ... Friday renewed their institutional commitment by signing a ... to expand the collaborative work in the areas ... energy and environmental sciences. , This renewal represents ... in December 2009 and is a framework to ...
(Date:9/22/2014)... YORK , Sept. 22, 2014 US ... US demand for specialty biocides is forecast to rise ... In volume terms, demand is projected to increase 1.3 ... same period. A strong rebound in construction expenditures will ... paint and coatings markets, while growth in consumer spending ...
(Date:9/22/2014)... Jose, California (PRWEB) September 22, 2014 ... Chitin and chitosan are natural biopolymers available in ... extracted from easily available resources such as shells ... and chitosan is mainly due to the high ... cellulose. Chitosan finds application in various industries owing ...
Breaking Biology Technology:Engineers show light can play seesaw at the nanoscale 2Lawrence Livermore Renews Pact with Georgetown University to Expand Research and Education in Science and Policy 2US Biocides Market 2US Biocides Market 3Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 2Emergence of New Application Areas to Drive the Global Chitin and Chitosan Market, According to New Report by Global Industry Analysts, Inc. 3
... SAN DIEGO, Oct. 15 PURE Bioscience (Nasdaq:,PURE), ... today reported revenues for the fiscal year ended ... 340% compared with $336,400 in the,prior fiscal year. ... taxes,of $(6,540,300), or $(0.24) per share, compared with ...
... Receptor ... CCR9 for Gastrointestinal Diseases, MOUNTAIN VIEW, Calif., ... initiated a Phase I clinical trial of CCX025,the company,s ... inhibits the chemokine receptor known as CCR9.,Structurally distinct from ...
... Oct. 15 The increased emphasis on,safety by ... medical,product development programs and requires rapid, cost-effective and,resource ... effect constructive change can be found in consulting ... clients from compliance errors,that can lead to adverse ...
Cached Biology Technology:PURE Bioscience Reports Fourth Quarter and Year End Results 2PURE Bioscience Reports Fourth Quarter and Year End Results 3PURE Bioscience Reports Fourth Quarter and Year End Results 4PURE Bioscience Reports Fourth Quarter and Year End Results 5PURE Bioscience Reports Fourth Quarter and Year End Results 6PURE Bioscience Reports Fourth Quarter and Year End Results 7ChemoCentryx Advances Second Orally Available CCR9 Antagonist CCX025 Into Clinical Development 2ChemoCentryx Advances Second Orally Available CCR9 Antagonist CCX025 Into Clinical Development 3ChemoCentryx Advances Second Orally Available CCR9 Antagonist CCX025 Into Clinical Development 4Ground Zero Pharmaceuticals Announces Expansion of Regulatory and Product Development Consulting Services 2Ground Zero Pharmaceuticals Announces Expansion of Regulatory and Product Development Consulting Services 3
(Date:9/22/2014)... Antarctic fishes that manufacture their own "antifreeze" proteins ... suffer an unfortunate side effect, researchers report: The ... resist melting even when temperatures warm. , ... of the National Academy of Sciences . , ... consequence of the evolution of antifreeze proteins in ...
(Date:9/22/2014)... manufacturing (AM), or 3D printing, has rapidly advanced ... components strong enough for structural applications. However, developing ... well as quality standards to test the manufactured ... Engineers at the University of Pittsburgh,s Swanson School ... and simulation (M&S) technology and new qualification standards ...
(Date:9/22/2014)... Conn. , Sept. 22, 2014 NXT-ID, ... company focused on the growing mobile commerce market, issues ... NASDAQ and the recent funding. ... completed an essential round of funding and joined the ... well as expand its other biometric and authentication products ...
Breaking Biology News(10 mins):Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 2Study: Antifreeze proteins in Antarctic fishes prevent freezingand melting 3Pitt engineers receive grants to enhance additive manufacturing 2Pitt engineers receive grants to enhance additive manufacturing 3NXT-ID Issues Shareholder Corporate Update 2NXT-ID Issues Shareholder Corporate Update 3NXT-ID Issues Shareholder Corporate Update 4
... to a friend's house or deciding on a political ... make decisions based on incomplete information and update those ... such sophisticated decision making in the cerebral cortex, which ... and little understood," according to Wako Yoshida and Shin ...
... little plastic model of a molecule he keeps in ... a ball. That's about the shape of a soy ... assistant professor of agricultural and biosystems engineering. Then he ... what happens when researchers add some glycerin ?a byproduct ...
... all have tastes we love, and tastes we hate. And yet, ... as we get older or we get tired of eating the ... study gives new evidence about what's going on in the brain ... something we once hated. , And although the study used ...
Cached Biology News:Where we change our mind 2Iowa State researchers improving plastics made from corn and soy proteins 2Tastes great! Study shows brain's response to pleasing -- and changing -- tastes 2Tastes great! Study shows brain's response to pleasing -- and changing -- tastes 3
FluoSpheres® biotin-labeled microspheres, 0.2 µm, yellow-green fluorescent (505/515) *1% solids*...
GM130 Immunogen: Recombinant purified rat GM130 Family / Subclass 1: Signal Transduction Storage: 4 C...
... Anti-NY-ESO-1, clone E978 ... : NM_001327 Immunogen ... protein Formulation: mouse ascites ... Quality Assurance: routinely evaluated ...
R26.4C...
Biology Products: