Navigation Links
Sarcoma Alliance Excited About New Drug Research
Date:6/25/2013

h-grade soft-tissue sarcomas for which doxorubicin is an appropriate front-line regimen.

Some critics have suggested that clinical trials be limited to only the sarcoma subtypes that show the greatest initial response. But Dr. Tap said he wouldn’t want to focus on one or two subtypes while other patients who might have responded go untested.

"A phase 2 study showed broad activity across sarcoma subtypes."

Some recent drug studies have looked at progression-free survival, i.e., how long a patient lives without the sarcoma returning or advancing. The TH-302 trial looks at whether patients live longer, Dr. Tap said.

“In sarcoma, in more than 30 years, we haven't had a new drug that we believe affects overall survival," he said, except those used for gastrointestinal stromal tumors.

Some people think TH-302 may fail because palifosfamide did, Beckert said. Both are chemical cousins of ifosfamide, but less toxic. Ifosfamide, an older drug, is sometimes paired with doxorubicin for chemotherapy. The palifosfamide trial combined it with doxorubicin in one arm vs. doxorubicin alone – similar to the TH-302 trial.

"They're different drugs,” Dr. Tap said. “It's like comparing apples and oranges. The key is the delivery method."

Unlike palifosfamide, TH-302 activates in tissue with low oxygen, and those conditions often exist in the center of a sarcoma, he said. This differs from other drugs that attack the edges of tumors, which have more blood vessels and thus, more oxygen.

For more information on the Sarcoma Alliance, go to http://sarcomaalliance.org

Read the full story at http://www.prweb.com/releases/2013/6/prweb10866921.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools
2. Edison Expands French Healthcare Sector Coverage With Initiation of Coverage on BioAlliance Pharma
3. Smart Consulting Group and The Catalyst Group Form Alliance to Supply Quality Compliance Consulting Services For the Pharmaceutical Industry
4. VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials
5. Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC
6. The Alliance for the Advancement of Adult Stem Cell Therapy and Research Recently Has Proven Stem Cells To Be Effective in Dilated Cardiomyopathy
7. Emergent Technologies and Caisson Biotech Form Strategic Alliance with Local Health Care Providers to Improve Delivery and Performance of a Therapeutic Drug
8. ClearPath Workforce Management CEO Appointed Co-chair of Northern California Leadership Forum for Woman Owned Business Alliance
9. Campbell Alliance to Release New Forward-Looking Industry Report on Deal-Making Trends at the 2013 BIO International Convention
10. SoundConnect Announces New Not-For-Profit Customer in Smart Card Alliance
11. Alliance to Feed the Future Congratulates Our Farmers, Supports Education for Future Generations on National Agriculture Day
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA ... disease. One of these latent viruses is the Epstein ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... by the theory, a study found that RA patients ... (1). , What is Microcompetition? , Dr. Hanan ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... of high throughput research solutions, today announced that ... companies, has received delivery of Freeslate’s CM ... form screening. , Lupin, headquartered in Mumbai, ... quality, affordable generic and branded formulations and Active ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, ... Foundation, the only national nonprofit organization solely dedicated to ... quality of life for those affected worldwide, will host ... Warrington Country Club in Warrington, Pa. , Each ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider ... major scientific, regulatory, business, and media events in ... , today announced its former associate Virginia Cox , ... office. Virginia Cox re-joins ... Commissioner for the Office of External Affairs at the U.S. ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... September 2009 Converting the trash that fills the ... both the growing energy crisis and to tackling carbon ... published in Global Change Biology: Bioenergy , reveals ... cut global carbon emissions by 80%. Biofuels produced ...
... of Michigan physicists have created the first atomic-scale ... the goal of producing "designer dots" that can ... called artificial atoms or nanoparticles---are tiny semiconductor crystals ... light-emitting devices and other technologies. Each dot is ...
... ... ClearTrial Clinical Trial Operations (CTO) software featuring new ClearTrial TRACK provides integrated planning, ... ... (PRWEB) September 29, 2009 -- ClearTrial ( www.cleartrial.com ), the leading provider of ...
Cached Biology Technology:U-M physicists create first atomic-scale map of quantum dots 2ClearTrial Launches Industry-first Software Platform for Integrating Clinical Trial Operations from Plan to Cash™, Driving Operational Efficiencies and Accelerating Clinical Development 2ClearTrial Launches Industry-first Software Platform for Integrating Clinical Trial Operations from Plan to Cash™, Driving Operational Efficiencies and Accelerating Clinical Development 3ClearTrial Launches Industry-first Software Platform for Integrating Clinical Trial Operations from Plan to Cash™, Driving Operational Efficiencies and Accelerating Clinical Development 4
(Date:4/15/2014)... Md., is home to hundreds of dedicated scientists, ... of the most cutting-edge Earth science innovation and ... innovation has earned a Goddard scientist the 2014 ... and Geography awards the Vega Medal every three ... in the fields of physical geography, exploration or ...
(Date:4/15/2014)... COLUMBIA, Mo. University of Missouri researchers have previously ... less motivated to exercise exists. In a new study, ... Veterinary Medicine, has found a potential link between the ... the speed at which mental maturation occurs. , For ... of either extreme activity or extreme laziness. Booth then ...
(Date:4/15/2014)... social behavior has developed over the course of evolution, ... gained new insights from the study of earwigs. "Young ... siblings share what is available amongst themselves, especially when ... the Evolutionary Biology section of the Institute of Zoology ... of biologists from Mainz University and the University of ...
Breaking Biology News(10 mins):Goddard scientist receives Vega Medal from King of Sweden 2Genetic pre-disposition toward exercise and mental development may be linked 2Sibling cooperation in earwig families gives clues to early evolution of social behavior 2
... Santa Barbara, CA The Bren School-based authors of a ... have observed toxicity to marine organisms resulting from exposure ... be toxic under similar conditions. Lead author and assistant ... Lenihan both Bren School professors and lead scientists at ...
... In August 2010, an entomologist at the University of California, Riverside ... never been seen in the United States until then. Nearly ... strongly suggesting that the wasp is well established in the country. ... millimeter long and arrived in North America from Europe. It ...
... 2012The time for commercial development of gene therapy has come. ... deserve access to the technology, which has demonstrated both its ... Human Gene Therapy in a provocative commentary ... and Human Gene Therapy (HGT) Methods are ...
Cached Biology News:Nano form of titanium dioxide can be toxic to marine organisms 2Wasp found in upstate New York shows up in Southern California 2Gene therapy is a 'disruptive science' ready for commercial development 2
... solution is an isotonic, balanced salt solution. It ... permits the storage of whole blood at refrigerator ... equal volume of blood is collected into a ... mixed. The solution is placed in a refrigerator ...
... Hollandes is a fixative useful for routine ... It is stable and will decalcify small ... Hollande's can be stained successfully with most ... solution stabilizes red blood cell membranes and ...
... a single-channel sample processing head, an 8-channel ... dispenser all in one compact, affordable product. ... tips, the Precision XS autoclavable and organic ... for transferring larger volumes. Intuitive Precision Power ...
... The RapidPlate 96/384 workstation offers precise 96 ... scalable format. Utilizing 100ul and 200ul disposable ... delivers excellent accuracy and precision across a ... rotary deck includes two positions that enable ...
Biology Products: