Navigation Links
Sarcoma Alliance Announces Tissue Bank to Help Researchers

Ann Arbor, Mich. (PRWEB) July 24, 2013

A national group of physicians and scientists who study sarcoma has opened a biospecimen bank to help research this rare cancer, the Sarcoma Alliance announced Wednesday.

SARC created the bank three years ago, and its staff and volunteers have talked to researchers about it, said President Denise Reinke, a nurse practitioner who also has an MS and MBA. Because the number of sarcoma researchers is relatively small, she said, SARC has never made a public statement about the bank before.

“We’ve never really advertised it or announced that we’re open for business,” she said, but she welcomes researchers to contact SARC if they have a specific study in mind. The nonprofit brings together physicians from different institutions to collaborate on clinical trials.

“We have been able to work together to make a difference for sarcoma patients,” said Reinke from her office in Ann Arbor, Mich.

There are more than 50 subtypes of sarcoma, a cancer of bone, muscle, nerve, fat and other connective tissues. It can arise anywhere in the body at any age, from newborn on up. It represents 15 percent of all childhood cancer cases and 1 percent of adult cancers, said Suzie Siegel of Tampa, a leiomyosarcoma survivor with the Sarcoma Alliance.

The Alliance was founded in 1999 in Mill Valley, Calif., to provide information and support to people affected by sarcoma. Siegel said it is sometimes confused with SARC, which stands for the Sarcoma Alliance for Research Through Collaboration. Both are nonprofits.

Since its founding 10 years ago, SARC has run 20 clinical trials across the country, Reinke said, and has collected thousands of biospecimens. “We’ve even got samples from the first trial.”

Tissue is saved frozen, in paraffin blocks and in unstained slides. Serum samples from blood draws are also frozen. Samples may come from different locations in the patient’s body and at different times, she said. For example, in a trial of the drug Gleevec and dermatofibrosarcoma protuberans, surgeons took fresh-frozen tissue before the patient got chemotherapy and afterward to gauge the drug’s effect.

“We have 20 paired samples, and we’re now looking for money to analyze them," she said.

SARC’s scientific leadership decides who receives samples, she said. Those leaders are divided into three committees: developmental therapeutics, concept review and clinical research. Robert Maki, MD, PhD, medical director of the sarcoma program at Mount Sinai Medical Center in New York, is the director of translational research.

“He moves among the committees; he’s the glue that holds them together,” Reinke said.

“The samples are being collected with annotated information along the way.” She said this includes the patient’s age, treatment, the response to treatment, survival, the location of the tumor, when the sample was taken, and whether the sample came from the original tumor or a metastasis. “Having annotated information is a critical component.”

Samples are stored at the biorepository at Nationwide Children’s Hospital in Columbus, Ohio, where SARC has bought space. Cooperative groups for other cancers save samples there, too, she said.

SARC doesn’t store all of its samples, Reinke said. “It costs to collect, save and analyze samples. In our IGF1R trial, for example, we had 25,000 serum samples." SARC’s scientific leadership decided they needed to keep only a third of those.

Comprehensive sarcoma centers also save biospecimens, often tied to patient details, said Dafydd G. Thomas, PhD, MD, co-director of the University of Michigan's Molecular Pathology Research Laboratory and its cancer center's Tissue and Molecular Pathology Core in Ann Arbor.

"University hospitals like Stanford, Moffitt and UM are sitting on a gold mine of tissue. I have over a thousand sarcoma specimens sitting in my freezers, linked to clinical data," he said. "Unfortunately, I do not have grant money to do much with this resource."

“We have a large tissue bank here at Memorial," said William Tap, MD, section chief for sarcoma oncology at Memorial Sloan-Kettering Cancer Center in New York. The National Cancer Institute has awarded a grant to the center to study sarcoma, and SARC is collaborating, Reinke said.

The NCI pulled together physicians, scientists and advocates who compiled a 2004 report that recommended “establishing a centralized sarcoma tumor and tissue repository.”

“It’s still critical to have a centralized bank, with the resources to properly manage it and establish quality control," Dr. Tap said. One of the challenges is cost, Reinke said, as is the high demand for biospecimens.

“Sometimes institutions don’t want to send them out, she said, because they don’t want to compromise their own institution’s ability to do research.”

For more information, go to the Sarcoma Alliance blog at:

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. Sarcoma Alliance Excited About New Drug Research
2. Study Scavenger and Announce Alliance Utilizing Smart Phone Capabilities to Bring Clinical Trials to Motivated Subjects
3. The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools
4. Edison Expands French Healthcare Sector Coverage With Initiation of Coverage on BioAlliance Pharma
5. Smart Consulting Group and The Catalyst Group Form Alliance to Supply Quality Compliance Consulting Services For the Pharmaceutical Industry
6. VG Energy Enters into a Strategic Alliance with DAK Renewable Research for LipidMax Field Trials
7. Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC
8. The Alliance for the Advancement of Adult Stem Cell Therapy and Research Recently Has Proven Stem Cells To Be Effective in Dilated Cardiomyopathy
9. Emergent Technologies and Caisson Biotech Form Strategic Alliance with Local Health Care Providers to Improve Delivery and Performance of a Therapeutic Drug
10. ClearPath Workforce Management CEO Appointed Co-chair of Northern California Leadership Forum for Woman Owned Business Alliance
11. Campbell Alliance to Release New Forward-Looking Industry Report on Deal-Making Trends at the 2013 BIO International Convention
Post Your Comments:
(Date:10/9/2015)... ROCKVILLE, Md. , Oct. 9, 2015 ... company developing next generation vaccines based on the ... into an exclusive worldwide licensing agreement with Astellas ... or prevention of any and all allergic diseases ... Therapeutics will receive an upfront payment of $300 ...
(Date:10/8/2015)... UK (PRWEB) , ... October 08, 2015 , ... Researchers ... literally see inside the living brain, providing a new tool to study how diseases ... is reported by Woo June Choi and Ruikang Wang of the UW Department of ...
(Date:10/8/2015)... Pa. , Oct. 8, 2015  Clarkston Consulting, ... the call for applications for the 2016 Clarkston Scholars ... a life sciences related field of study, a $10,000 ... selected Clarkston Scholar will receive exposure to the life ... in Pennsylvania Bio events over the course of the ...
(Date:10/8/2015)... , Oct. 8, 2015  Today, DuPont and ... for genome editing, jointly announced a strategic alliance. ... cross-licensed their respective patent portfolios, with DuPont receiving ... in major row crops, and non-exclusive rights in ... --> --> In ...
Breaking Biology Technology:
... Gretel ventured into the forest, they left a trail ... world, cellular phones, Global Positioning System (GPS), WiFi, and ... friends, family, and colleagues while helping us find our ... ubiquity of such devices, with few exceptions, today,s firefighters ...
... Kendle (Nasdaq: KNDL ), a leading, ... of its senior clinical development experts will present ... Association (DIA) 47th Annual Meeting, June 19-23, 2011, ... including the benefits of hybrid monitoring; finding an ...
... New Generation of the Ziehm Vision RFD Offers,Lower-Cost ... has launched a new generation of the Ziehm Vision,RFD mobile ... it to be used over an almost unlimited period,of time, ... to its mobility and significantly lower investment costs,the Ziehm Vision ...
Cached Biology Technology:
(Date:9/30/2015)... Sept. 30, 2015  With nearly 300,000 Americans living ... new SCIs estimated to reach 12,500 annually, the role ... Resource Services for Independent Living (SCRS-IL) is increasingly ... California opening doors to independence for ... and services, notably assistive technology services and education. ...
(Date:9/29/2015)... SUNNYVALE, Calif. , Sept. 29, 2015 ... technology improves employee productivity while also saving energy ... features such as Low Power Active Mode and embedded ... workplace transformation Fujitsu today shows that ... of new and refreshed models to its enterprise desktop ...
(Date:9/28/2015)... Sept. 28, 2015  The monitoring of vital ... body temperature, is an essential component of patient ... of deterioration in a patient,s condition. However, in ... are typically taken during routine observation rounds only ... patient deteriorates between these observation rounds, the warning ...
Breaking Biology News(10 mins):
... VTT Technical Research Centre of Finland indicates that there is ... sold in Finland as regards fuel consumption in normal driving. ... using six used cars of different make under laboratory conditions. ... fuel consumption is significantly higher with 95E10 petrol than with ...
... A group of scientists at the Instituto Gulbenkian de Cincia, ... skeleton and organ size. The team, led by Florence Janody, ... the proteins that regulates the skeleton of the cell also ... and proliferation. Their findings have implications for cancer research, as ...
... organ in the human body that metabolizes foreign compounds such ... liver as an alarm system, researchers are starting to better ... their effects on the human body. One ... the Virginia Tech Institute of Critical Technology and Applied Science,s ...
Cached Biology News:
Rabbit polyclonal to Olfactory Receptor LS189744 ( Abpromise for all tested applications)....
Recognizes the VZV nucleocapsid by indirect immunofluorescence and immunoprecipitation. Shows cross-reactivity to HSV....
Mouse monoclonal [11C9] to Zeralenone ( Abpromise for all tested applications). Antigen: Chemical / Small Molecule conjugated to BSA: Zeralenone...
AK6 Antibody...
Biology Products: