Navigation Links
Santen and MacuSight Announce Collaboration and License Agreement for Sirolimus in Ocular Diseases and Conditions
Date:6/2/2008

olimus is a highly-potent, broad-acting compound that has demonstrated the ability to combat disease through multiple mechanisms of action including immunosuppressive, anti-angiogenic, anti-migratory, anti-proliferative, anti-fibrotic and anti-permeability activity. Based on the versatility associated with these multiple mechanisms of action, MacuSight believes that its sirolimus product may serve as a potentially highly-efficacious therapeutic for a wide range of ocular diseases and conditions, including the treatment and prevention of wet AMD and DME.

Phase 1 clinical trials in patients with wet AMD and DME have shown MacuSight's proprietary formulation of sirolimus to be safe and well-tolerated in all doses tested when delivered by either subconjunctival or intravitreal injection. Furthermore, patients who participated in these studies exhibited improvements in visual acuity that were consistent with anatomical retinal changes following a single administration of sirolimus.

About Wet Age-Related Macular Degeneration (AMD)

Age-related macular degeneration (AMD) is the leading cause of visual loss in the western world. This disease of the aging eye results in loss of the sharp, central vision that is necessary for clearly seeing objects and undertaking routine tasks including reading and driving. AMD occurs in both wet and dry forms, with the wet form accounting for the vast majority of cases of AMD-related blindness and progressing much more rapidly than dry.

About Diabetic Macular Edema

Diabetic macular edema (DME) is a serious manifestation of diabetic retinopathy that involves retinal swelling brought on by the leaking of fluid from small blood vessels within the macula. As the condition develops, central vision becomes blurred. DME can progress fairly rapidly and over just a few years can lead to permanent visual loss. There is a significant unmet need to both reverse the visual loss associated with DME and to help delay the
'/>"/>

SOURCE MacuSight, Inc.; Santen Pharmaceutical Co., Ltd.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Quest PharmaTech Announces Positive Results from Phase I Clinical Trial of its Photodynamic Therapy for Actinic Keratosis
2. GeneNews announces management changes to support commercialization of ColonSentry(TM)
3. AMDL Announces New GOODNAK Consumer Anti-Aging Products for Use in Skin Renewal Treatments
4. Pharmacyclics Announces It Received Nasdaq Notice of Compliance
5. Renhuang Pharmaceuticals, Inc. Announces Solid Fourth Quarter and Fiscal Year 2007 Results
6. Haemonetics and Octapharma AG Announce Plasma Collection Technology Contract
7. FASgen Diagnostics, LLC Announces Production and Investment Agreement With Tetracore, Inc.
8. China Biologic Products Announces SFDA Approval for the Production and Sale of Human Albumin 12.5g/vial (25%, 50 ml)
9. HistoRx Announces Expanded Access of AQUA(R) Technology to 900+ Researchers at Dana-Farber/Harvard Cancer Center
10. Favrille Announces Workforce Reduction
11. AMT Announces Presentations During the 11th Annual Meeting of the ASGT
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... Calif. , Sept. 15, 2014  FlexTech ... (RFP) for flexible, printed product demonstrators (demos) and ... two-stage RFP process with pre-proposals due on October ... 2015.  Funds for proposals ultimately selected are provided ... have a significant cost share by the proposing ...
(Date:9/15/2014)... 15, 2014 Bioptigen announced ... OCT system for the optical device metrology and pre-clinical ... S4410 SDOCT for Contact Lens Metrology is designed ... high complexity contact lens, IOL structures, and donor tissues. ... complete contact lens immersed in a hydration bath (saline), ...
(Date:9/15/2014)... Paula, CA (PRWEB) September 15, 2014 ... long term implantable silicones for the medical device ... responsive silicone gel for the implantable medical device ... a unique crosslink technology delivering a silicone gel ... The Dual Matrix technology consists of two ...
(Date:9/15/2014)... Rome, GA (PRWEB) September 15, 2014 ... ( http://www.hydrodynamics.com ) announced today that it will ... Verdes Estates, CA ( http://www.proteaf.com ) for implementing ... in high value continuous processing. Continuous flow ... in the chemical, pharmaceutical and petrochemical markets for ...
Breaking Biology Technology:FlexTech Alliance Issues 2015 Request for Proposals in Flexible, Printed Electronics 2Bioptigen Introduces Deep Imaging OCT System for Contact Lens Metrology 2Applied Silicone Launches Silicone Gel System with Dual Matrix Technology 2Hydro Dynamics Partners with the Continuous Flow Chemistry Experts of Proteaf Technologies 2
... - While much of the attention paid to ... from jellyfish, it is the company's emerging business model that ... , ,Quincy Bioscience is based in Madison's University Research ... University of Wisconsin-Milwaukee , making it a virtual poster child ...
... Madison, Wis. - Imago Scientific Instrument Corp. ... releasing an upgrade to its main product line. , ... location of atoms, to research facilities in the semiconductor, ... can offer key insights into how a material's properties ...
... all the emotional arguments, and all the IP-driven features, and ... great race for global competitiveness, economic development equals broadband connectivity ... is the need for speed. Thats all the consumer needs ... , , AT&T's Project Lightspeed offers data ...
Cached Biology Technology:Biotech firm has strokes, Alzheimer's in its sights 2Biotech firm has strokes, Alzheimer's in its sights 3Biotech firm has strokes, Alzheimer's in its sights 4Broadband blues: Don't fall for Lightspeed hype 2Broadband blues: Don't fall for Lightspeed hype 3Broadband blues: Don't fall for Lightspeed hype 4Broadband blues: Don't fall for Lightspeed hype 5
(Date:9/15/2014)... thrive in the oceans, there must be enough ... areas, extreme oxygen-starvation produces "dead zones" that decimate ... dissolved oxygen levels decline, energy is increasingly diverted ... resulting in impacts on the ecology and biogeochemistry ... years, oxygen minimum zones (OMZs) have expanded due ...
(Date:9/15/2014)... Research suggests that genes that affect hearing and cognitive ... the ability to understand and perceive rhythm, pitch, timbre, ... authors of a BioEssays article explain that ... within a population, with the majority of individuals having ... a complex trait attributable to several underlying genes, and ...
(Date:9/15/2014)... account where hippopotamuses are demonstrably shown swimming or floating ... if they can,t swim, how did they reach and ... for the methods, patterns, and timing of the colonization ... Madagascar) may need to be reconsidered. , "Although land ... are not currently supported by positive geological evidence, ...
Breaking Biology News(10 mins):Decoding virus-host interactions in the oxygen-starved ocean 2Decoding virus-host interactions in the oxygen-starved ocean 3Decoding virus-host interactions in the oxygen-starved ocean 4Decoding virus-host interactions in the oxygen-starved ocean 5
... France to NASCAR, competitors and fans know that speed is ... to use elements like aerodynamic drafting, which makes it easier ... in front -- is also critical. But in some ... pack who experiences reduced drag, while the followers encounter more ...
... University scientists concerned about lethal mold infections have found a ... gene, called srbA, allows molds to thrive during infections even ... author of a paper published in the Nov. 7 issue ... the mold becomes much more vulnerable to lack of oxygen ...
... nesting along the Mississippi River and other areas are ... says a researcher from Iowa State University. Fred ... has studied turtle nesting habits and also accumulated research ... of the turtles to find out when they make ...
Cached Biology News:Following the leader can be a drag, according to student's research on flapping flags 2Montana State University researchers find gene that regulates mold's resistance to drugs 2Turtles alter nesting dates due to temperature change says ISU researcher 2
... Daltonics and Bruker BioSpins Metabolic Profiler ... studies, and analysis of complex mixtures. ... an optional Avance NMR spectrometer and ... and statistical analysis for applications like:,Assessment ...
... movements in a Morris Water Maze. Tracks ... predefined sequence of trials.The Spatial Behavior line is ... video camera, frame grabber, and feature extraction software ... and up to 6 moving animals. Software ...
... Object Records behavior directed toward examining a novel ... a family of instruments all built around a ... and that can track two fields at once ... automatically extracts animal positions and records them, but ...
... ACS Reagent Grade C 19 H 9 ... 691.95 PRODUCT SPECIFICATIONS Form: Powder Clarity of ... pH 3.0 - Yellow pH 4.6 ... dye in agarose and acrylamide gel electrophoresis. ...
Biology Products: