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Sanofi-aventis U.S. to Acquire Oral Chronic Lymphocytic Leukemia Treatment
Date:5/11/2009

enefit such as prolongation of survival or relief of symptoms have not been performed. Studies providing a direct comparison of the clinical efficacy and safety of orally administered fludarabine phosphate relative to intravenously administered fludarabine phosphate have not been performed. The most common adverse reactions include myelosuppression (neutropenia, thrombocytopenia and anemia), fever and chills, infection, and nausea and vomiting. Serious opportunistic infections have occurred in patients with CLL treated with fludarabine phosphate.

About CLL

CLL is a slow-growing cancer of the white blood cells and bone marrow, which arises predominantly in older age groups (the majority of people with CLL are at least 50 years of age). According to the Leukemia & Lymphoma Society, CLL is the most prevalent leukemia -- with approximately 15,000 new cases diagnosed in 2008. An estimated 90,000 people are living with CLL today. More than 95 percent of all CLL cases have B-cell involvement.

About sanofi-aventis

Sanofi-aventis U.S. is an affiliate of sanofi-aventis, a leading global pharmaceutical company that discovers, develops and distributes therapeutic solutions to help improve the lives of patients. Sanofi-aventis is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY).

For more information, www.sanofi-aventis.us or www.sanofi-aventis.com.

    U.S. Contact
    Lisa Buffington
    908-981-6569
    Lisa.Buffington@sanofi-aventis.com

Forward Looking Statements

This press release contains forward-looking statements as defined in the Private
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