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Sanofi Pasteur's Investigational H5N1 Influenza Vaccine Achieves High Immune Response at low Dosage
Date:9/17/2007

ine to provide cross-protection to variants of the H5N1 strains is ongoing.

Sanofi pasteur has committed, in the event of a pandemic being declared by the World Health Organization (WHO), to producing the largest possible number of doses of its most advanced pandemic influenza vaccine in the shortest possible time. In order to increase its capacity, sanofi pasteur initiated clinical trials with a novel adjuvant aimed at dramatically reducing the amount of antigen needed to elicit a protective immune response to the H5N1 strain currently identified by global health authorities and experts as a potential source for the next pandemic.

According to the WHO, the next influenza pandemic could result in 1 million to 2.3 million hospitalizations and 280,000 to 650,000 deaths in industrialized nations alone. Its impact is expected to be even more devastating in developing countries.

With production of 170 million doses of influenza vaccine in 2006, sanofi pasteur confirmed its leadership as the world's largest manufacturer of seasonal influenza vaccine, supplying a large portion of the estimated global production of about 350 million doses(1). Sanofi pasteur's Vaxigrip(R) and Fluzone(R) influenza virus vaccines are licensed in over 100 countries.

Pandemic Influenza Overview

Influenza is a disease caused by a highly infectious virus that spreads easily from person to person, primarily when an infected individual coughs or sneezes. An influenza pandemic is a global epidemic of an especially virulent virus, newly infectious for humans, and for which there is no preexisting immunity. This is why pandemic strains have such potential to cause severe morbidity and mortality. In an attempt to minimize the impact of a pandemic, many countries are developing national and transnational plans against a possible influenza pandemic situation.

Sanofi Pasteur and Pandemic Preparedness

Sanofi pasteur is committed to global pandemic preparedness. As t
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SOURCE Sanofi Pasteur
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