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Sanofi Pasteur Responds to Nation's Need for Hib Vaccine With Increased Supply
Date:6/25/2009

oximately half the Hib vaccine in the U.S. each year, but we have been able to substantially increase supply in 2009 to help make up for the shortfall created by the other manufacturer's continued absence."

"The reinstatement of the booster dose of Hib vaccine is important due to recent epidemiologic trends," said Dr. Gary Overturf, professor of pediatrics and pathology at the University of New Mexico. "The deferral of the booster dose was always meant to be a temporary situation, but now that nearly 18 months have passed, we have seen several cases of Hib disease primarily among unimmunized and partially immunized children. This could represent an increase of Hib carriage and transmission from older non-symptomatic children to those children whose parents refused vaccination or are too young to have received their full primary series. While this is a hypothesis, it's reassuring to know we won't have to put it to the test, and can begin immunizing with the full schedule again."

The CDC recommends that children receive a primary series of Hib vaccinations during infancy and a booster dose at 12-15 months of age. Sanofi Pasteur has been working closely with the CDC since December of 2007 to meet the country's Hib immunization needs, and maximize the availability of the vaccine to the greatest number of children. As is the case with many vaccines, Hib vaccine manufacturing is a complex biological process with lengthy production cycles.

To maintain adequate supplies of Hib vaccine throughout the reinstatement period, the CDC is encouraging all health-care providers to administer the booster dose of Hib vaccine to children older than 12 months of age who were previously deferred, at the next regularly-scheduled medical encounter. This practice will help ensure a steady stream of available supply, which remains constrained in the short term.

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