Navigation Links
Sangart, Inc. Reports Positive Phase IIa Data for Novel Oxygen Therapeutic Agent MP4OX in Severe Trauma Patients
Date:8/31/2010

SAN DIEGO, Aug. 31 /PRNewswire/ -- Sangart, Inc., today announced positive results from its Phase IIa proof-of-concept study of MP4OX (oxygenated pegylated hemoglobin) in severely injured trauma patients with hemorrhagic shock causing lactic acidosis. The study demonstrated that MP4OX, when given in addition to standard of care, was effective at decreasing lactate levels in treated patients. During hemorrhagic shock, inadequate perfusion of critical organs can lead to insufficient oxygenation of tissues, which can be detected by an increase in lactate levels. MP4OX is a novel oxygen therapeutic agent that is designed to provide rapid oxygen delivery to ischemic tissues.

Study data show a statistically significant greater immediate and sustained decrease of lactic acid in patients treated with MP4OX compared to patients in the control group. The study also found that a greater proportion of patients treated with MP4OX were able to attain normal lactate levels as early as four hours post-treatment. Furthermore, data demonstrated a strong trend toward outcomes benefits through multiple measures, including reducing the average total number of days patients spent in hospital. In patients treated with MP4OX, the median hospital stay was half that of the control group. Serious adverse events were of equal rates and similar in nature between the MP4OX-treated and control groups.

"Trauma patients suffer organ dysfunction from shock and lack of oxygen supply to vital tissues.  Prolonged lactic acidosis, a marker of shock, correlates with a worse outcome and higher mortality rate. This study suggests that MP4OX has the ability to improve oxygen delivery to the body and subsequently reduce organ failure and other complications," said Karim Brohi, Professor of Trauma Sciences at Barts and the London School of Medicine & Dentistry and lead study investigator. "We are excited by the results from this study as they suggest that MP4OX has the potential to
'/>"/>

SOURCE Sangart, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Sangart, Inc. Announces Key Executive Appointments and Company Restructuring
2. Sangart, Inc. Completes Series F Funding Round
3. Sangart, Inc. Receives European Orphan Drug Designation for the Use of MP4CO in Patients With Sickle Cell Disease
4. SCOLR Pharma, Inc. Reports Second Quarter 2008 Financial Results
5. AutoImmune Inc. Reports 2008 Second Quarter Financial Results
6. Par Pharmaceutical Reports Second Quarter 2008 Results
7. ISTA Pharmaceuticals Reports Second Quarter 2008 Financial Results
8. Pharmos Corporation Reports 2008 Second Quarter Results
9. Halozyme Therapeutics Reports 2008 Second Quarter Financial Results
10. MGT Capital Investments Reports Second Quarter 2008 Financial Results and Provides Update on Recent Developments
11. BMP Sunstone Reports Second Quarter 2008 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... Parsippany, NJ (PRWEB) July 22, 2014 ... analytical, precision, portable, and mechanical balances and scales, ... precision balances has won Laboratory Equipment magazine’s 2014 ... is the second consecutive year the Explorer was ... readers. The annual Readers’ Choice Awards celebrates “excellence ...
(Date:7/22/2014)... and SHENZHEN, China , ... Co., LTD, (BGI Tech), a subsidiary of BGI, ... global launch of a new human whole exome ... This newly offered service includes in-depth bioinformatics analysis ... prices until December 31, 2014. ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Quorum Review IRB, ... service for large clinical trials called Quick Step™ . ... designed to address the research industry’s need for seamless study ... service is available for studies planning 50 or more North ... combined planned North American site count of 80 or more. ...
(Date:7/22/2014)... 2014 The next session of ... and will comprise of the increasingly popular ‘Base SAS’ ... is a series of technical hands-on classes for entry-level ... reach the next step in their professional careers. , ... by Jennifer Kang, Senior Statistician at Genentech and former ...
Breaking Biology Technology:OHAUS Explorer Voted “Best Balance” in Laboratory Equipment’s 2014 Readers’ Choice Awards 2BGI Tech Launches Human Whole Exome Sequencing Service on Complete Genomics' Advanced Platform 2BGI Tech Launches Human Whole Exome Sequencing Service on Complete Genomics' Advanced Platform 3Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 2Quorum Review IRB Launches New Quick Step™ Service for Large Clinical Trials 3Clinovo TechTrainings: Next Session of SAS and CDISC Classes Start 9th September, 2014 2Clinovo TechTrainings: Next Session of SAS and CDISC Classes Start 9th September, 2014 3
... March 21, 2011 Cell Therapeutics, Inc. ("CTI") (Nasdaq ... its randomized pivotal trial of pixantrone for the treatment ... trial is now open to patient enrollment. The trial, ... will compare a combination of pixantrone plus rituximab to ...
... 18, 2011 Driving value for customers is critical to ... points between a customer and an organization, there has to ... an organization to succeed in the marketplace. ... Practices, LLC., noted in this month,s special issue of PharmaVoice ...
... 2011 BioMarin Pharmaceutical Inc. (Nasdaq: BMRN ... Approach for PKU Treatment) in an abstract (Abstract #91 ... presented by Barbara Burton, MD at the 2011 annual ... Canada.  ADAPT, which was funded by a grant from ...
Cached Biology Technology:Cell Therapeutics Initiates Pixantrone PIX-R Pivotal Trial for Treatment of Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma 2Cell Therapeutics Initiates Pixantrone PIX-R Pivotal Trial for Treatment of Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma 3Cell Therapeutics Initiates Pixantrone PIX-R Pivotal Trial for Treatment of Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma 4Best Practices, LLC Showcases Its Expertise in Customer Relationship Management 2First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU 2First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU 3First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU 4First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU 5First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU 6First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU 7First-of-Its-Kind Study Suggests Importance of Routine Mental Health Screening in the Care of Patients Suffering From Genetic Disease PKU 8
(Date:7/22/2014)... purified crystals that split light with uncanny precision ... and, potentially, computers that manipulate light instead of ... such as etching them with a precise beam ... , Now, researchers at Princeton and Columbia universities ... scientists to customize and grow these specialized materials, ...
(Date:7/22/2014)... milk helps make their bones strong or that fish is food ... if something is good for us, it must surely taste bad? ... Research , when children hear about the benefits of healthy food, ... food is presented to children as making them strong or as ... read or count, they would conclude the food is not as ...
(Date:7/22/2014)... trees and not just asphalt and recreation equipment reduces ... Colorado Boulder study. , Working on class assignments or ... youth, according to a paper published in the journal ... of the first of its kind to focus on ... stress. , "Many schools already offer stress management programs, ...
Breaking Biology News(10 mins):Technique simplifies the creation of high-tech crystals 2Technique simplifies the creation of high-tech crystals 3Natural-terrain schoolyards reduce children's stress, says Colorado University-Boulder study 2Natural-terrain schoolyards reduce children's stress, says Colorado University-Boulder study 3
... of Medicine (BUSM) have demonstrated that certain T cells ... pro-inflammatory response in people with type 2 diabetes (T2D). ... a loss in homeostasis in this group of T ... Barbara Nikolajczyk, PhD, an associate professor of ...
... the winners of its international travel grants to ... the Baltimore Convention Center in Baltimore, Maryland, March ... is to foster and initiate further interaction between ... financial difficulties. Recipients of this competitive award ...
... rap as vermin and pests because they seem to thrive ... in Africa for the past 50 million years. From ... a stable and plentiful source of food, says paleontologist Alisa ... fossils are proving their usefulness to scientists as they help ...
Cached Biology News:Biophysical Society announces winners of 2011 International Travel Awards 2Biophysical Society announces winners of 2011 International Travel Awards 3Biophysical Society announces winners of 2011 International Travel Awards 4Rodents were diverse and abundant in prehistoric Africa when our human ancestors evolved 2Rodents were diverse and abundant in prehistoric Africa when our human ancestors evolved 3