Navigation Links
Sangamo BioSciences Provides Update on Phase 1 Safety Trial of SB-728-T for HIV/AIDS
Date:11/18/2009

RICHMOND, Calif., Nov. 18 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that data from the University of Pennsylvania investigator sponsored Phase 1 safety study of Sangamo's zinc finger nuclease (ZFN) based product, SB-728-T, for HIV/AIDS were inadvertently and prematurely disclosed on the internet.

Data were presented in a student course at the University of Pennsylvania School of Medicine from a single subject treated with SB-728-T who, as part of the study, began a structured treatment interruption (STI) from his antiviral drug therapy four weeks after SB-728-T treatment. This subject was reported to have stable CD4+ and ZFN-modified T-cell levels and an undetectable viral load one month post STI initiation. Previous studies have shown that in subjects undergoing an STI, the average time to detection of an increase in viral load is two to four weeks. While this subject continues to demonstrate stable CD4+ T-cell counts and stable levels of ZFN-modified T-cells, by six weeks post STI initiation the subject had a detectable viral load.

As previously stated, the company and the University of Pennsylvania intend to provide updates on the two ongoing Phase 1 SB-728-T trials only at appropriate scientific or medical meetings.

About Sangamo

Sangamo BioSciences, Inc. is focused on the research and development of novel DNA-binding proteins for therapeutic gene regulation and modification. The most advanced ZFP Therapeutic(TM) development program is currently in Phase 2 clinical trials for evaluation of safety and clinical effect in patients with diabetic neuropathy and ALS. Sangamo also has two Phase 1 clinical trials to evaluate safety and clinical effect of a ZFP Therapeutic for the treatment of HIV/AIDS. Other therapeutic development programs are focused o
'/>"/>

SOURCE Sangamo BioSciences, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Sangamo BioSciences Announces Presentation at Merriman Curhan Fords Investor Summit 2009
2. Sangamo BioSciences Announces Third Quarter 2009 Conference Call and Webcast
3. Sangamo Announces Pricing of Public Offering of Common Stock
4. Sigma-Aldrich(R) and Sangamo BioSciences Announce Major Expansion of ZFP Technology License Agreement
5. Sangamo BioSciences Announces Presentation at the UBS Global Life Sciences Conference
6. Sangamos Zinc Finger Nuclease Technology Used to Efficiently Modify Human Stem Cells
7. Sangamo BioSciences Reports Second Quarter 2009 Financial Results
8. Sangamo BioSciences Announces Second Quarter 2009 Conference Call and Webcast
9. Sangamo BioSciences Announces Presentation at the Needham Life Sciences Conference
10. Sangamo BioSciences Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research
11. Sangamo BioSciences Announces Publication in Nature of the Use of Zinc Finger Nucleases to Accelerate Precision Trait Stacking in Commercial Crop Species
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... 30, 2014 Each year in ... require medical attention. In the military, burn injury ... to battlefield medical care. More than 800 service ... Burn wounds heal slowly, remain inflamed and often ... physically debilitating and functionally damaging. While developments in ...
(Date:9/29/2014)... Va. , Sept. 29, 2014  Ten ... the fields of cartilage repair, regeneration, allograft reconstruction ... from around the world gathered to discuss the ... Health Institute of Regenerative Medicine symposium, Cartilage ... . Topics included Orthopedic Biosurgery, Minced Juvenile Allograft, ...
(Date:9/29/2014)... global challenges in food security, emerging diseases and ... study published online in Science Express ... University of Arizona College of Agriculture and Life ... team of nine scientists has reviewed progress in ... medicine and environmental management using approaches that consider ...
(Date:9/29/2014)... 2014 According to ... Product (Modifying Enzymes, DNA Polymerase, Acetylase, Methyltransferase, ... Reagents), by Research Area (Developmental Biology, Oncology), ... 2019", published by MarketsandMarkets, provides a detailed ... current market trends, and strategies impacting the ...
Breaking Biology Technology:Faster Healing with Fewer Scars 2World Renowned Experts Discuss Future Of Cartilage Regeneration 2World Renowned Experts Discuss Future Of Cartilage Regeneration 3Evolutionary biology: It's not just for textbooks anymore 2Evolutionary biology: It's not just for textbooks anymore 3Epigenetics Market Worth $783.17 Million by 2019 2Epigenetics Market Worth $783.17 Million by 2019 3Epigenetics Market Worth $783.17 Million by 2019 4
... California, San Diego electrical engineers have created experimental ... to highly efficient thin-film solar cells of the ... as electron superhighways that carry electrons kicked loose ... electron-attracting electrode and this scenario could boost ...
... Morrow, who will graduate from Rensselaer Polytechnic Institute on ... his days as an elementary school student, pulling apart ... developed two innovations that could vastly improve magnetic data ... everything from ink on counterfeit currency to tissue in ...
... improvement is achieved by the use of an ultra-thin aluminum ... brings a breakthrough in the use of solar energy a ... cent (in absolute terms) may at first glance appear modest, ... the performance of their products. This is because higher efficiency ...
Cached Biology Technology:Nanowires may boost solar cell efficiency, UC San Diego engineers say 2Nanowires may boost solar cell efficiency, UC San Diego engineers say 3Nanowires may boost solar cell efficiency, UC San Diego engineers say 4Commencement 2008: Student innovation could improve data storage, magnetic sensors 2New efficiency record for solar cells 2
(Date:9/29/2014)... received a five-year, $6 million grant for clinical ... and development of safe and effective treatments for ... the National Institutes of Health, National Institute on ... Medication Development for Cocaine Use Disorder to oversee ... decisions on moving forward with more expensive large-scale ...
(Date:9/29/2014)... culture, mathematics is often deemed inaccessible or esoteric. Yet ... important role in our daily lives and a decisive ... often behind the scenes. , UC Santa Barbara,s ... and an assistant professor of mechanical engineering, often works ... his recent research published in the Proceedings of ...
(Date:9/29/2014)... The U.S. Department of Energy Joint Genome Institute ... facility, has announced that 32 new projects have ... (CSP). From sampling Antarctic lakes to Caribbean waters, ... underneath the water table in forested watersheds, the ... DOE mission-relevant science can be extracted. , ...
Breaking Biology News(10 mins):New VCU center to target cocaine addiction 2At the interface of math and science 2At the interface of math and science 3At the interface of math and science 42015 DOE JGI's science portfolio delves deeper into the Earth's data mine 22015 DOE JGI's science portfolio delves deeper into the Earth's data mine 32015 DOE JGI's science portfolio delves deeper into the Earth's data mine 42015 DOE JGI's science portfolio delves deeper into the Earth's data mine 52015 DOE JGI's science portfolio delves deeper into the Earth's data mine 62015 DOE JGI's science portfolio delves deeper into the Earth's data mine 72015 DOE JGI's science portfolio delves deeper into the Earth's data mine 82015 DOE JGI's science portfolio delves deeper into the Earth's data mine 9
... release is available in Spanish . , ... viable alternative to petroleum-based packaging products, according to a ... Tomasula for a new book, "Dairy-Derived Ingredients: Food ... by an international team of contributors and published by ...
... "original insect wrangler" who tamed 25,000 roaches, and trained ... of the Lambs," headlines the Southwest,s first Social Insect ... Garden. Designed for inquiring minds and families, the ... Arizona State University, their favorite critters and the public. ...
... breeding and high-intensity x-rays is being used by ... Research Council (BBSRC) to explore the possibility of ... potentially life-saving mineral enriched flour. The research is ... quarterly highlights magazine of BBSRC. Scientists from ...
Cached Biology News:Potential of dairy-based package wraps outlined 2Insect wranglers invade the garden at Southwestern science EXPO 2Scientists using X-ray vision to produce more nutritious flour 2
... The Rapid DNA Ligation ... or blunt-end DNA fragments in ... C. Depending on the ... DNA concentration) or concatemeric (high ...
... Polynucleotide Kinase catalyzes the transfer ... to the 5-terminus of polynucleotides ... 5-hydroxyl group. The enzyme, purified ... be used to phosphorylate RNA, ...
...
... CryoMed Freezers for IVF are designed for ... control, ease of setup and operation, and ... status are continuously displayed on the control ... data are printed by way of the ...
Biology Products: