Navigation Links
Sangamo BioSciences Announces ZFP Therapeutic Data From Nerve Regeneration Program at Society for Neuroscience Meeting
Date:11/7/2007

Statistically Significant Improvements in Function and Tissue Preservation

with ZFP TF Treatment in Spinal Cord Injury Model

SAN DIEGO, Nov. 7 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today the presentation of preclinical data from its ZFP Therapeutic(TM) program in nerve regeneration at Neuroscience 2007, the 37th Annual Meeting of the Society for Neuroscience. A statistically significant effect on both recovery of hind-limb function and spinal cord tissue preservation was demonstrated in a severe model of spinal cord injury (SCI) following treatment at the time of injury with a zinc finger DNA-binding protein activator of vascular endothelial growth factor (VEGF ZFP TF).

"We are excited by the statistically significant improvements in measures of both nerve health and, more importantly, nerve function after treatment with our VEGF ZFP TF," said Dale Ando, M.D. Sangamo's vice president of therapeutic development and chief medical officer. "Data generated in these studies are consistent with other data from a variety of models that suggest that our ZFP TF activator of VEGF expression has regenerative effects on nerves and increases the density of blood vessels in and around the treated tissue.

We believe that these effects will prove therapeutically important in conditions that involve nerve damage including diabetic neuropathy, ALS, stroke and traumatic injuries to the brain, spinal cord and other nerves. We are very pleased to collaborate with Dr. Michael Fehlings, senior author of this study, who is world-renown for his work on SCI and has significant clinical trial experience in this area."

Sangamo is currently developing SB-509, a plasmid fo
'/>"/>

SOURCE Sangamo BioSciences, Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related biology technology :

1. Sangamo BioSciences Presents Data Demonstrating In Vivo Protection Against HIV Infection by CCR5-ZFN Therapeutic
2. Sangamo BioSciences to Present at the UBS Global Life Sciences Conference
3. Sangamo BioSciences to Present at the 2007 BIO InvestorForum
4. Sangamo BioSciences Announces Third Quarter 2007 Conference Call and Webcast
5. YM BIOSCIENCES ANNOUNCES COMPLIANCE WITH AIM RULE 26
6. Selection of Development Candidate Triggers $0.5 Million Milestone Payment to Ardea Biosciences, Inc.
7. ImmuneRegen BioSciences Files 8-K that Highlights Enclosed Shareholder Letter Discussing Recent Achievements and Outlook
8. ONCOSCIENCE AG, THE EUROPEAN PARTNER OF YM BIOSCIENCES, ANNOUNCES COMPLETION OF PATIENT ENROLLMENT IN PHASE III BRAIN CANCER TRIAL OF NIMOTUZUMAB
9. Pressure BioSciences, Inc. Reports Second Quarter 2007 Financial Results and Provides Business Update
10. YM BIOSCIENCES, EUROPEAN PARTNER, ONCOSCIENCE AG, ANNOUNCES INITIATION OF ADVANCED NIMOTUZUMAB TRIALS IN ADULT GLIOMA AND PANCREATIC CANCER
11. Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2007
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2013)... (PRWEB) June 20, 2013 The ... outcomes measurement because of variability in Patient-Reported Outcomes ... sensitivity of such scales to culture, their cross-cultural ... laboratory testing for the successful development of a ... steps for maximizing cross-cultural equivalence of scales assessing ...
(Date:6/20/2013)... 20, 2013 Based on its recent ... Sullivan presents bitop AG with the 2013 European ... The company,s path-breaking extremolyte platform enables a naturally-derived ... dry eye or dry nose syndrome, and respiratory ... to revolutionize how allergies are treated. ...
(Date:6/20/2013)... June 20, 2013 Over the years, ... has received many questions that can be summed up in ... Owner of GLM Displays, Matt Lunser, sat down and ... between his products and offer some useful tips on how ... , “This buyer's guide is meant to help our clients ...
(Date:6/20/2013)... Belatrix Software, the leading global Nearshore Agile ... latest initiative – the Belatrix Software Innovation University (BSIU). ... and business and technology executives to participate in a ... the initiative is to fuel business leaders with what ... innovation efforts. It’s that inspiration that has the ...
Breaking Biology Technology:Cross-Cultural Qualitative Research for Simultaneous Scale Development, New Life Science Webinar Hosted by Xtalks 2Frost & Sullivan Presents bitop AG with the 2013 New Product Innovation Award in the Extremolytes Therapeutics Market 2Frost & Sullivan Presents bitop AG with the 2013 New Product Innovation Award in the Extremolytes Therapeutics Market 3Frost & Sullivan Presents bitop AG with the 2013 New Product Innovation Award in the Extremolytes Therapeutics Market 4Belatrix Software Kicks off Major Innovation Effort and Invites Innovation Expert to Share How Agile + Design Thinking Accelerate Product Innovation 2
... 2011 K-V Pharmaceutical Company (NYSE:  KVa/KVb) announced today ... divest Nesher Pharmaceuticals, Inc., its generics subsidiary, and the ... Inc. for approximately $60 million in cash. The transaction ... KV,s 2012 fiscal year, subject to customary closing conditions. ...
... they left a trail of breadcrumbs to find their ... System (GPS), WiFi, and Bluetooth are the digital signals ... helping us find our location and map our routes. ... few exceptions, today,s firefighters still rely on 20th-century radios, ...
... Background : The U.S. House of Representatives ... appropriations bill, co-sponsored by Rep. Don Young (R-AK) and Rep. ... Drug Administration approval of salmon grown from AquaBounty Technologie,s AquAdvantage ... ten of the total 435 House members. ...
Cached Biology Technology:K-V Pharmaceutical Announces Divestiture of Generics Business to Zydus 2K-V Pharmaceutical Announces Divestiture of Generics Business to Zydus 3K-V Pharmaceutical Announces Divestiture of Generics Business to Zydus 4K-V Pharmaceutical Announces Divestiture of Generics Business to Zydus 5K-V Pharmaceutical Announces Divestiture of Generics Business to Zydus 6K-V Pharmaceutical Announces Divestiture of Generics Business to Zydus 7Wireless 'breadcrumbs' that wont become toast when baked...or soggy when hosed 2Wireless 'breadcrumbs' that wont become toast when baked...or soggy when hosed 3Statement by Ronald L. Stotish, Ph.D., President and CEO of AquaBounty Technologies 2
(Date:6/19/2013)... , June 20, 2013 Based ... market, Frost & Sullivan recognizes geneOnyx Limited with ... New Product Innovation. geneOnyx leverages a DNA testing ... create an on-the-spot genetic test for anti-aging cosmetics. ... DNA collection procedure from saliva to examine single ...
(Date:6/19/2013)... network in Tanzania is playing a vital role in ... west in response to climate and environmental changes, according ... Using data on savannah birds from the Tanzanian Bird ... over recent decades - the researchers found that they ... move to areas further west where dry seasons are ...
(Date:6/19/2013)... 2013   Mercy Medical Center ... for conducting on-demand, Hemoglobin A 1c ... as analysis of important red blood cell, ... new system enables the hospital to provide ... and their patients, which can improve treatment ...
Breaking Biology News(10 mins):Frost & Sullivan Applauds geneOnyx for its DNA Testing Solution for the Personalized Cosmeceuticals Market 2Frost & Sullivan Applauds geneOnyx for its DNA Testing Solution for the Personalized Cosmeceuticals Market 3Frost & Sullivan Applauds geneOnyx for its DNA Testing Solution for the Personalized Cosmeceuticals Market 4Protected areas provide African birds with stepping stones to survival 2Mercy Lab Offers Faster On-demand Diabetes Testing, Cellular Studies 2Mercy Lab Offers Faster On-demand Diabetes Testing, Cellular Studies 3Mercy Lab Offers Faster On-demand Diabetes Testing, Cellular Studies 4
... In much of Africa, a herd of cattle is ... dowry, funeral fund, symbol of wealth, and hedge against drought. ... cow to disease can spell ruin. Yet a grievous ... puts annual losses from disease at $40 billion, some twenty-five ...
... HOUSTON -- (Aug. 17, 2010) -- The most robust statistical ... Eve" -- the maternal ancestor of all living humans -- ... University study was based on a side-by-side comparison of 10 ... lived using a very different set of assumptions about the ...
... could lead to a brand new class of drugs to ... and back pain without numbing the whole body. ... Council (BBSRC) and working at UCL (University College London), have ... pain are regulated by molecules inside cells called small RNAs. ...
Cached Biology News:Cow vaccines go vroom 2Cow vaccines go vroom 3Mother of all humans lived 200,000 years ago 2Mother of all humans lived 200,000 years ago 3Scientists uncover Achilles heel of chronic inflammatory pain 2
... Shimadzus GCMS-QP2010s Gas Chromatograph/Mass Spectrometer, utilizing ... the GCMS-QP2010 Plus, offers high throughput ... an excellent performance-to-cost ratio. Like the ... constant linear velocity for optimum separation, ...
... combines a single-channel sample processing head, an ... reagent dispenser all in one compact, affordable ... pipette tips, the Precision XS autoclavable and ... available for transferring larger volumes. Intuitive Precision ...
... world of discovery races ever faster, you need ... fast track. So our constant focus is on ... research. Thats why our Biomek 3000 Laboratory Automation ... advanced as it is flexible. By integrating all ...
... Zymeds MaxArray Rabbit Tissue Arrays contain 60 ... slides. Each package contains 4 unstained slides and ... your reference. Each slide contains 15 different tissues ... 60 tissue samples per slide. Each tissue sample ...
Biology Products: