Navigation Links
Sangamo BioSciences Announces Presentation Of Clinical Data From Alzheimer's Disease Program
Date:11/15/2013

the nerve cells of the brain were not deteriorating significantly over this time period
  • Efficacy assessments such as mental state (MMSE), cognition (ADAS-Cog) and activities of daily living (ADAS-ADL), demonstrated no evidence of accelerated decline over 24 months, although the sample size was too small to allow any conclusions to be drawn regarding improvement in symptoms.
  • About the Ongoing CERE-110 Phase 2 Study
    Forty-nine (49) patients with mild to moderate AD were treated with a single administration of CERE-110 at 10 clinical sites throughout the U.S. Approximately half of the patients received CERE-110 while the other half received an appropriate sham (placebo) surgery control treatment. Patients will be followed for a minimum of two years with respect to safety, brain imaging, as well as measures of cognitive function and quality of life - standard tests used in Alzheimer's clinical trials. The clinical study was carried out in collaboration with the Alzheimer's Disease Cooperative Study (ADCS) based at the University of California San Diego (UCSD) and funded by a grant from the National Institute on Aging (NIA). Enrollment was completed in March 2013 and data are expected in 2015.

    About CERE-110
    CERE-110 is an adeno-associated viral (AAV) vector that encodes the gene for nerve growth factor (NGF), a naturally occurring protein that maintains survival of nerve cells in the brain. CERE-110 is surgically injected into the nucleus basalis of Meynert (NBM), a brain region where cholinergic nerve cell degeneration occurs in AD. Delivery of NGF using an AAV vector has the potential to induce sustained expression of NGF, resulting in long-lasting protection and preservation of cholinergic nerves. The cholinergic system is important in memory and cognitive function, and a restoration of the function of this system may slow the progression of the disease and possibly improve memory in individuals with AD.

    About Alzheimer's
    '/>"/>

    SOURCE Sangamo BioSciences, Inc.
    Copyright©2012 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6

    Related biology technology :

    1. Sangamo BioSciences Reports Third Quarter 2013 Financial Results
    2. Sangamo BioSciences Announces Closing Of $74.2 Million Public Offering Of Common Stock And Exercise Of Over-Allotment Option
    3. Sangamo BioSciences Proposes Public Offering Of Common Stock
    4. Biotech Firms Receive Orphan Drug Designations, Release Clinical Data, Achieve Goals, Enter Acquisitions & Forecast Revenues - Research Report on Aegerion, Oncolytics, Merrimack, Sangamo, and PDL
    5. Sangamo BioSciences Announces Presentation At The 2013 Wedbush Life Sciences Management Access Conference
    6. Sangamo BioSciences Announces Presentation at the Bank of America Merrill Lynch 2013 Health Care Conference
    7. Sangamo BioSciences Announces Presentation At The Needham Healthcare Conference
    8. Sangamo BioSciences Announces Presentation At Regen Med Investor Day
    9. Sangamo BioSciences Announces Fourth Quarter And Full Year 2012 Conference Call And Webcast
    10. Sangamo BioSciences Announces Presentation At The Lazard Capital Markets Healthcare Conference
    11. Sangamo BioSciences Announces Presentation At The Stifel Nicolaus 2012 Healthcare Conference
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:9/23/2014)... , Sept. 23, 2014 /PRNewswire/ - Portage Biotech Inc. ... Exchange: PBT.U), is pleased to announce that its ... added two more  consultants to its team for ... uses a new proprietary cell permeable peptide platform ... anti-inflammatory cargo into the eye. ...
    (Date:9/23/2014)... 23, 2014 Equashield ( ...     Devices  (CSTD) for hazardous drugs, ... Medical Technology Corporation.  Equashield,s leading CSTD has been ... , China and ... to expand globally, and throughout the ...
    (Date:9/23/2014)... September 23, 2014 Healthcare ... globe will convene at the Society for ... be held October 26-28 in Houston, Texas ... and practice in individualized integrative cancer care. ... nurses, psychologists, nutritionists, naturopaths, acupuncturists, and other ...
    (Date:9/22/2014)... Pearl's Premium Ultra Low Maintenance Lawn Seed ... seed this week with the release of their Pearl's ... the fact that it is time to plant now ... , As of the date 6/4/13, Pearl's Premium had ... experts and the media including: The National Gardeners ...
    Breaking Biology Technology:Portage Announces New Consultants for its PPL-003 Development Programs 2Portage Announces New Consultants for its PPL-003 Development Programs 3Portage Announces New Consultants for its PPL-003 Development Programs 4Equashield Enters Taiwan Following Expansion to Australia, Japan, China 2International Medical Experts to Discuss Latest Integrative Oncology Research and Its Translation to Personalized Clinical Care at 11th International Conference of SIO 2International Medical Experts to Discuss Latest Integrative Oncology Research and Its Translation to Personalized Clinical Care at 11th International Conference of SIO 3Pearl's Premium Ultra Low Maintenance Lawn Seed Announces A Major Breakthrough In Drought Tolerant Grass Seed 2
    ... to 26 in Kansas City. , ... Rockville, MD ... Annual Scientific Meeting (ASM) will be held in Kansas City, Mo., ... with the USP experts responsible for establishing internationally recognized standards for ...
    ... 3 ESA Biosciences, a Magellan,Biosciences company and ... for pharmaceutical development and QA/QC, life science, and,analytical-chemistry ... Frost & Sullivan North American Technology Innovation Award ... Sullivan will present the,award to ESA,s Vice President ...
    ... HOUSTON, Sept. 3 US Oncology Specialty, LP, ... the Occupational Excellence Achievement Award from the National,Safety ... award is presented to companies who produce the ... To be eligible, organizations must report,days away from ...
    Cached Biology Technology:USP's 2008 Annual Scientific Meeting to Convene Scientific Experts from Around the World 2USP's 2008 Annual Scientific Meeting to Convene Scientific Experts from Around the World 3ESA Receives 2008 Frost & Sullivan North American Technology Innovation Award for Development of Integrated Metabolomics Systems 2ESA Receives 2008 Frost & Sullivan North American Technology Innovation Award for Development of Integrated Metabolomics Systems 3US Oncology Pharmaceutical Distribution Service Wins National Safety Council Award 2
    (Date:9/22/2014)... that after a long stay in the Intensive Care ... remain behind in patients, intestines. The team tested these ... when provoked by conditions that mimic the body,s stress ... mBio , the online open-access journal of the American ... treatment of ICU patients who can develop a life-threatening ...
    (Date:9/22/2014)... cut grass in recent years has been identified as ... says the aroma also summons beneficial insects to the ... plant signals the environment via the emission of volatile ... for parasitic wasps to come to the plant that ... insect," said Dr. Michael Kolomiets, Texas A&M AgriLife Research ...
    (Date:9/22/2014)... Scientists have discovered a key molecular cog in a ... of circadian (daily) rhythms based on temperature. , Transcription ... based on external stresses such as light, rain, ... team of researchers at USC has isolated one, called ... here and there as needed while in keeping it ...
    Breaking Biology News(10 mins):Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 2Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 3Mown grass smell sends SOS for help in resisting insect attacks, researchers say 2Mown grass smell sends SOS for help in resisting insect attacks, researchers say 3Genetic switch regulates a plant's internal clock based on temperature 2
    ... January 14, 2013 Using an innovative approach, scientists ... structure of Ltn1, a recently discovered "quality-control" protein that ... and animals. Ltn1 appears to be essential ... also be relevant to human neurodegenerative diseases, for an ...
    ... 2013Taking a vitamin D supplement and drinking cow,s milk are ... D is in a child,s body, new research has found. ... colour and exposure to the sun, according to Dr. Jonathon ... "Early childhood is a critical stage in human development, so ...
    ... is Everywhere" tenet of bacterial distribution in the ocean, ... "bipolar" species of bacteria that occur in the Arctic ... they found even fewer bipolar species than would turn ... everywhere. "That suggests that there are forces that are ...
    Cached Biology News:Scientists discover structure of protein essential for quality control, nerve function 2Scientists discover structure of protein essential for quality control, nerve function 3Supplements and cow's milk play biggest roles in determining vitamin D levels in children 2MBL scientists find 'bipolar' marine bacteria, refuting 'everything is everywhere' idea 2MBL scientists find 'bipolar' marine bacteria, refuting 'everything is everywhere' idea 3
    ... to MKK6 (phospho S207) ( Abpromise ... Antigen: Synthetic phosphopeptide ... phosphorylation site of Serine 207 (V-D-S ... Gene ID: 5608 ...
    Mouse monoclonal [1Q17] to TGE Virus peplomer ( Abpromise for all tested applications)....
    CD45/CD34 combination 50 tests...
    XPC Immunogen: XPC (NP_004619, 141 a.a. ~ 251 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
    Biology Products: