Navigation Links
Sangamo BioSciences Announces Presentation Of Clinical Data From Alzheimer's Disease Program
Date:11/15/2013

the nerve cells of the brain were not deteriorating significantly over this time period
  • Efficacy assessments such as mental state (MMSE), cognition (ADAS-Cog) and activities of daily living (ADAS-ADL), demonstrated no evidence of accelerated decline over 24 months, although the sample size was too small to allow any conclusions to be drawn regarding improvement in symptoms.
  • About the Ongoing CERE-110 Phase 2 Study
    Forty-nine (49) patients with mild to moderate AD were treated with a single administration of CERE-110 at 10 clinical sites throughout the U.S. Approximately half of the patients received CERE-110 while the other half received an appropriate sham (placebo) surgery control treatment. Patients will be followed for a minimum of two years with respect to safety, brain imaging, as well as measures of cognitive function and quality of life - standard tests used in Alzheimer's clinical trials. The clinical study was carried out in collaboration with the Alzheimer's Disease Cooperative Study (ADCS) based at the University of California San Diego (UCSD) and funded by a grant from the National Institute on Aging (NIA). Enrollment was completed in March 2013 and data are expected in 2015.

    About CERE-110
    CERE-110 is an adeno-associated viral (AAV) vector that encodes the gene for nerve growth factor (NGF), a naturally occurring protein that maintains survival of nerve cells in the brain. CERE-110 is surgically injected into the nucleus basalis of Meynert (NBM), a brain region where cholinergic nerve cell degeneration occurs in AD. Delivery of NGF using an AAV vector has the potential to induce sustained expression of NGF, resulting in long-lasting protection and preservation of cholinergic nerves. The cholinergic system is important in memory and cognitive function, and a restoration of the function of this system may slow the progression of the disease and possibly improve memory in individuals with AD.

    About Alzheimer's
    '/>"/>

    SOURCE Sangamo BioSciences, Inc.
    Copyright©2012 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6

    Related biology technology :

    1. Sangamo BioSciences Reports Third Quarter 2013 Financial Results
    2. Sangamo BioSciences Announces Closing Of $74.2 Million Public Offering Of Common Stock And Exercise Of Over-Allotment Option
    3. Sangamo BioSciences Proposes Public Offering Of Common Stock
    4. Biotech Firms Receive Orphan Drug Designations, Release Clinical Data, Achieve Goals, Enter Acquisitions & Forecast Revenues - Research Report on Aegerion, Oncolytics, Merrimack, Sangamo, and PDL
    5. Sangamo BioSciences Announces Presentation At The 2013 Wedbush Life Sciences Management Access Conference
    6. Sangamo BioSciences Announces Presentation at the Bank of America Merrill Lynch 2013 Health Care Conference
    7. Sangamo BioSciences Announces Presentation At The Needham Healthcare Conference
    8. Sangamo BioSciences Announces Presentation At Regen Med Investor Day
    9. Sangamo BioSciences Announces Fourth Quarter And Full Year 2012 Conference Call And Webcast
    10. Sangamo BioSciences Announces Presentation At The Lazard Capital Markets Healthcare Conference
    11. Sangamo BioSciences Announces Presentation At The Stifel Nicolaus 2012 Healthcare Conference
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:4/27/2015)... 2015  Together with its customers, Elekta raised EUR ... Barcelona . The funds will be ... mission to improve cancer care, specifically radiation oncology care, ... no patient should be denied potentially life-saving treatment simply ... with hospitals and clinics around the world to take ...
    (Date:4/24/2015)... SD and Tempe, AZ (PRWEB) April 24, 2015 ... Technology and Arizona State University (ASU) have entered into ... joint projects. , A memorandum of agreement signed by ... long distance learning, student success and other services particularly, ... resources. , “We have complementary strengths and a ...
    (Date:4/24/2015)... DIEGO , April 24, 2015  Pfenex Inc. ... the development of biosimilar therapeutics including high value and ... its follow-on public offering of 6,000,000 shares of its ... $15.50 per share. Of the shares being offered, 2,610,000 ... shares are being offered by existing stockholders. Pfenex will ...
    (Date:4/24/2015)... Seoul Semiconductor announced the expansion of its proprietary ... market. In recent months, there have been ... markets such as Russia, South America, and Southeast ... as streetlight and area lighting, tunnel lighting, industrial ... 2005 the Acrich technology from Seoul Semiconductor has ...
    Breaking Biology Technology:Elekta helps raise $33,000 to bring radiation treatment to developing countries 2Elekta helps raise $33,000 to bring radiation treatment to developing countries 3South Dakota Mines, Arizona State University Pave Way for Cooperative Research 2Pfenex Inc. Announces Pricing Of Follow-on Offering 2Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2
    ... VANCOUVER , June 30 /PRNewswire/ - Sirius Genomics, ... has been appointed Senior Director of Business Development. , ... "Sirius Genomics is on ... Kam,s extensive background in partnering with both global pharmaceutical and medical ...
    ... Tekscan, Inc. ... the traditional pin connection, Tekscan is now offering a lower-cost termination method to enable OEM ... , ... -- Tekscan, Inc. announces a new lower-cost connection option for its custom FlexiForce® sensors ...
    ... A ... users sports performance , ... Denmark (PRWEB) June 30, 2010 -- Recent researches have found scientific evidence that proves ... researchers from Denmark revealed that the level of enhancement of performance due to the use ...
    Cached Biology Technology:Sirius Genomics Announces Appointment of Senior Director of Business Development 2Lower-Cost ZIF and LIF-Compatible Connection Option for Tekscan Custom Force Sensors 2Recent Study Reports Reveals that HGH May Aid Performance 2
    (Date:4/1/2015)... 1, 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market, announces the second ... is underway to early access pre-order customers. ... at retail outlets including Walmart, Target, AT&T, Dunkin, Donuts, ... was accepted at all outlets and very easy to ...
    (Date:3/30/2015)... and Markets ( http://www.researchandmarkets.com/research/lc9bnl/global_gesture ) has announced ... in Automotive Sector 2014-2018" report to their offering. ... market in Automotive Sector to grow at a CAGR ... recognition is the ability of a device to identify ... recognition technology can be 2D-based or 3D-based. It uses ...
    (Date:3/24/2015)... 24, 2015   NexID Biometrics LLC, whose ... needs, today announced the beginning of shipments of version ... The company, based in Potsdam, N.Y. ... Connect:ID Expo, which began here today at the Walter ... 2.0 of its SDK boosts the accuracy rate range ...
    Breaking Biology News(10 mins):NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4Global Gesture Recognition Market in Automotive Sector Report 2015 - Growing Number of Partnerships 2NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2
    ... Radula buccinifera is nothing of the kind. The species ... It has gone on to be the most commonly collected ... Zealand, according to results of research led by Dr Matt Renner ... and morphological evidence show that what was thought to be one ...
    ... time quantified the energy cost to aquatic animals when they ... Studying fibreglass casts of sea turtles in a wind tunnel, ... drag by less than five per cent for large adult ... more than 100 per cent on smaller or juvenile animals. ...
    ... RIVERSIDE, Calif. Cowpea is a protein-rich legume crop that ... and their livestock. Immensely important in many parts of the ... the diet and economy of hundreds of millions of people ... a growing world population, new cowpea varieties with desirable traits, ...
    Cached Biology News:2 grants to UC Riverside boost scientists' efforts in developing improved cowpea varieties 22 grants to UC Riverside boost scientists' efforts in developing improved cowpea varieties 32 grants to UC Riverside boost scientists' efforts in developing improved cowpea varieties 42 grants to UC Riverside boost scientists' efforts in developing improved cowpea varieties 52 grants to UC Riverside boost scientists' efforts in developing improved cowpea varieties 6
    ...
    ... Cell Dissociation Buffers are membrane-filtered ... salts chelating agents and cell-conditioning agents ... balanced salt solution or Ca2+- ... dissociation of mammalian cells from support ...
    ... are membrane-filtered isotonic and enzyme-free aqueous ... cell-conditioning agents in either Ca2+- and ... Ca2+- and Mg2+-free phosphate-buffered saline ... from support substrates and each other ...
    ... Antibody Modification Services ,,GenScript offers ... labeling and antibody fragmentation. Labeling antibodies ... for visualization and quantitation of the ... is preferable to use only the ...
    Biology Products: