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Salk scientists use Amazon Cloud to view molecular machinery in remarkable detail
Date:2/1/2013

that provides access to supercomputing via the Internet, allowing massive computing tasks to be distributed over banks of computers.

To make PALM more practical for use in biomedical research, the team wrote a computer script that allows any biologist to upload and process PALM images using Amazon Cloud.

As a demonstration, Cang, Lippincott-Schwartz and post-doctoral researcher Ying Hu reconstructed the images of podosomes, which are molecular machines that appear to encourage cancer cells to spread. In one instance, they dropped the time needed to process an image from a whole day to 72 minutes. They also imaged tubulin, a protein essential for building various structures within cells. In that case, they were able to drop the time from nine days to under three and a half hours.

Their new paper provides a how-to tutorial for using the code to process PALM images through Amazon Cloud, helping the other labs achieve similar increases in speed.


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Contact: andy Hoang
ahoang@salk.edu
619-861-5811
Salk Institute
Source:Eurekalert  

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