Navigation Links
SRI Awarded $150 Million NIAID-DAIDS Contract to Provide Development and Manufacturing Support for Promising HIV-Prevention Products
Date:12/6/2016

MENLO PARK, Calif., Dec. 6, 2016 /PRNewswire/ -- SRI International has been awarded a contract of up to $150 million from the National Institutes of Health's National Institute of Allergy and Infectious Diseases and the Division of AIDS (NIAID-DAIDS) to support the manufacturing and characterization of HIV microbicides and other non-vaccine pre-exposure (PreP) agents. Under the seven-year contract, SRI will provide a comprehensive suite of preclinical product development services for candidate HIV-prevention products that emerge from investigator-initiated studies or from collaborations with outside companies and organizations.

An estimated 36.7 million people worldwide are currently living with HIV, and the development of highly effective strategies to prevent further spread of the virus remains one of the highest priorities for the NIAID and DAIDS.1 The availability of safe, effective, and acceptable non-vaccine biomedical prevention products could play a major role in the worldwide reduction of the estimated 5,000 new HIV infections per day.2 However, as promising products emerge, advancement through the development process has been a significant barrier, particularly for academic groups and small to mid-sized companies.

Under the contract issued by DAIDS, SRI Biosciences, a division of SRI International, will manufacture and characterize high-quality drug products to support the progression of promising microbicide and PreP agents through both preclinical and clinical studies. SRI will also provide support for specific activities required by the U.S. Food and Drug Administration to move products into clinical testing.

"Since the early 2000s, researchers at SRI International have been involved in drug development activities to help move many microbicides, PrEP agents, and multipurpose prevention technologies through IND-enabling studies," said Gita Shankar, Ph.D., director, Formulations R&D, Center for Pharmaceutical and Chemical Technologies, SRI Biosciences, and principal investigator for the DAIDS contract. "We are very pleased to be given an opportunity to contribute to the acceleration of promising HIV products into clinical testing and the creation of a sustainable pipeline of prevention products and strategies."

SRI has broad experience with similar studies for DAIDS and for many other divisions of the National Institutes of Health, as well as for private sponsors. Since 2010, Dr. Shankar has led the development of a multipurpose HIV-prevention microbicide bioadhesive gel, which is funded by another NIAID grant (R33AI098658-03). Between 2000 and 2004, SRI manufactured drug products and supplied clinical sites with microbicides and contraceptive controls such as Gynol II® Vaginal Jelly, sodium cellulose sulfate 6% gel, ACIDFORM™ gel and BufferGel®. 

This project has been funded in whole or in part with Federal funds from the Division of AIDS (DAIDS), National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN272201600010I.

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

About SRI Biosciences
SRI Biosciences, a division of SRI International, integrates basic biomedical research with drug and diagnostics discovery and preclinical and clinical development. SRI International, a research center headquartered in Menlo Park, California, creates world-changing solutions to make people safer, healthier, and more productive.

1 No. NAID-DAIDS-NIHAI2015029

2 http://www.unaids.org/en/resources/fact-sheet

 

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/sri-awarded-150-million-niaid-daids-contract-to-provide-development-and-manufacturing-support-for-promising-hiv-prevention-products-300373910.html


'/>"/>
SOURCE SRI International
Copyright©2016 PR Newswire.
All rights reserved


Related biology technology :

1. S&D Marketing Advertising Awarded WBENC Certification
2. Boston Heart Diagnostics Awarded $450,000 in Tax Incentives from the Massachusetts Life Sciences Center
3. Cellular Dynamics and Coriell Institute for Medical Research Awarded Multi-Million Dollar Grants from California Institute for Regenerative Medicine to Manufacture and Bank Stem Cell Lines
4. BioPharm Insight Journalist Awarded Fellowship by Association of Health Care Journalists
5. Selenium, Ltd. Awarded $500,000 SBIR Grant for Biofouling Prevention Technology
6. Nanotherapeutics Awarded Defense Department Contract for Advanced Development and Manufacturing of Medical Countermeasures
7. Provitro Biosciences Awarded First-Ever U.S. Patent For Large-Scale Production Of Bamboo Plants
8. Empire Genomics Awarded SBIR Phase I Grant from NCI for Companion Diagnostics for Multiple Myeloma
9. University of Huddersfield awarded £93k award from the EPSRC
10. Puritan Awarded New Canadian Patent for PurFlock® Ultra Flocked Swab
11. ConfometRx Awarded Patent on GPCRs that Contain a Stabilizing IC2 Fusion Protein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... Washington, USA (PRWEB) , ... May 22, 2017 ... ... SPIE Optics and Photonics 2017 in San Diego, California, this August will ... reality, solar fuels, and autonomous vehicles. , SPIE Optics and Photonics, the largest ...
(Date:5/23/2017)... ... 2017 , ... Kathy Goin is joining myClin ... years of expertise in establishing and leading clinical operations at Sponsors including Trevena, ... therapist, through a variety of leadership roles in Clinical Operations, to her current ...
(Date:5/23/2017)... ... 2017 , ... Customers often prefer PLC and network ... METTLER TOLEDO has released two new videos that show how they have solved ... ACT350 into Siemens and Allen Bradley PLCs is easy and fast. ...
(Date:5/22/2017)... ... May 22, 2017 , ... ... is exhibiting in booth B2 at the Association for Pathology Informatics Annual ... , In addition to demonstrating its Cancer Diagnostic Cockpit and Consultation Portal, Inspirata ...
Breaking Biology Technology:
(Date:3/22/2017)... , March 21, 2017 Vigilant ... company serving law enforcement agencies, announced today the appointment ... as director of public safety business development. ... law enforcement experience, including a focus on the aviation ... his most recent position, Mr. Sheridan served as the ...
(Date:3/20/2017)... ALLENTOWN, Pa. , March 20, 2017 ... PD 2.0 personal spirometer and Wellness Management System (WMS), ... Founded in 2010, PMD Healthcare is a ... Company with a mission dedicated to creating innovative solutions ... of life. With that intent focus, PMD developed the ...
(Date:3/13/2017)... 2017 Future of security: Biometric Face Matching software  ... ... DERMALOGs Face Matching enables to match face pictures against each other or ... individuals. (PRNewsFoto/Dermalog Identification Systems) ... "Face Matching" is the fastest software for biometric Face Matching on the market. ...
Breaking Biology News(10 mins):