Navigation Links
SGX Pharmaceuticals Provides Update on SGX523 Clinical Trials
Date:3/27/2008

Company Presents Today at BioCentury Future Leaders Conference

SAN DIEGO, March 27 /PRNewswire-FirstCall/ -- SGX Pharmaceuticals (Nasdaq: SGXP) is providing an update today on the SGX523 clinical program.

In January 2008, the Company initiated two parallel, multi-center Phase 1 clinical trials of SGX523 in patients with solid tumor cancers. The first trial has been designed to examine twice daily, oral dosing on a continuous 28-day cycle and the second trial has been designed to examine interrupted dosing (a repeating 21 day cycle of 14 days on therapy followed by 7 days off).

In both trials, the Company observed dose limiting toxicity earlier than anticipated. The toxicity is of a nature that was not anticipated based on the preclinical profile of SGX523. The interrupted dosing trial started at a higher dose than the continuous dosing trial and no patients are currently receiving treatment on the interrupted dosing trial. In the continuous dosing trial, patients are continuing to be treated at a lower dose level, and the Company is evaluating the safety and efficacy of treatment at that dose level.

"From the initial clinical data, the profile of SGX523 appears to be different than the preclinical data would suggest," said Mike Grey, president and chief executive officer of SGX Pharmaceuticals. "On the continuous dosing trial, patients continue on study at the initial dose and we may explore whether alternative doses and schedules are safe and efficacious. We continue the preclinical development of the BCR-ABL inhibitor SGX393 and the second MET inhibitor SGX126. In addition, we are targeting the identification of two development candidates this year from our drug discovery programs to further enhance our pi
'/>"/>

SOURCE SGX Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Alseres Pharmaceuticals to Host 2007 Financial Results Conference Call
2. Millennium Biotechnologies, Inc. Signs Marketing and Distribution Agreement with Ferring Pharmaceuticals
3. Nereus Pharmaceuticals Initiates Clinical Trial of NPI-2358 in Non-Small Cell Lung Cancer Following Encouraging Phase 1 Data
4. XTL Biopharmaceuticals Signs $108 Million Deal for the Licensing of its Pre- Clinical Program in Hepatitis C to Presidio Pharmaceuticals
5. SGX Pharmaceuticals to Present at the BioCentury Future Leaders in the Biotech Industry Conference
6. Raptor Pharmaceuticals Corp. Enters Agreements to Advance Clinical Pipeline
7. LigoCyte Pharmaceuticals Finalizes Agreement for $28M Series C Financing Round
8. Jazz Pharmaceuticals, Inc. Announces Expansion of Senior Debt
9. Vion Pharmaceuticals to Host Conference Call to Discuss 2007 Fourth Quarter and Year-End Financial Results
10. MiddleBrook Pharmaceuticals to Present at Lehman Brothers Global Healthcare Conference
11. Cadence Pharmaceuticals to Present at the Cowen and Company 28th Annual Health Care Conference on March 20, 2008 in Boston
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... (PRWEB) July 12, 2014 ... various reagents used in the life science ... the life science reagents market towards remarkable ... manufacturers and providers of life science reagents. ... Report: http://www.transparencymarketresearch.com/life-sciences-reagents-analytical-reagents.html . , The global ...
(Date:7/11/2014)... , July 11, 2014 ... to announce the appointment of John P. Donoghue ... Biotech   in  Geneva . The ... Campus Biotech in Geneva , has ... recognised neuroscientists. John P. Donoghue , founder of ...
(Date:7/10/2014)... Canada (PRWEB) July 10, 2014 ... present in very low abundance and are often ... challenging and time-consuming. , Join presenters Dr. Rowel ... and Dr. John Anders, Head of Quality at ... spectrometer-based approach that can speed detection and quantitation ...
(Date:7/10/2014)... Poway, CA (PRWEB) July 10, 2014 Robert ... Regenerative Veterinary Medicine company, is proud to announce the relaunch ... Pets, launching with a new series called “ What are ... to give an honest and straightforward foundation in the basics ... an educated decision on the right type of treatment when ...
Breaking Biology Technology:Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 2Transparency Market Research: Life Science Reagents Market- PCR Reagent Kits, Cell and Tissue Culture, Flow Cytometry, Electrophoresis and Chromatography 3John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 3Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3
... research that gives literal meaning to the term "power ... nanofibers that could one day be woven into clothing ... properties that allow them to convert into electricity the ... "This technology could eventually lead to wearable ,smart ...
... 12 CoAxia™, Inc. of Maple Grove, MN ... randomized, controlled, pivotal trial of NeuroFlo™ Perfusion Augmentation Therapy as ... to complete data collection and analysis of results in Q3 ... US FDA. , Ischemic stroke is one of the largest ...
... ... announce that Maastricht based forensics lab DNalysis have successfully rolled out PatentSafe, protecting their ... secure electronic repository. , ... Bracknell, UK (PRWEB) Feburary 10, 2010 -- Amphora Research Systems is pleased to ...
Cached Biology Technology:New fiber nanogenerators could lead to electric clothing 2CoAxia Announces Completion of Enrollment in Ischemic Stroke Trial 2CoAxia Announces Completion of Enrollment in Ischemic Stroke Trial 3Independent Forensics Company DNalysis Implement Amphora's PatentSafe Solution to Preserve and Secure Findings 2Independent Forensics Company DNalysis Implement Amphora's PatentSafe Solution to Preserve and Secure Findings 3
(Date:7/14/2014)... have shown how the main psychoactive ingredient in cannabis ... Research published today reveals the existence of previously unknown ... in shrinking tumours. , It is hoped that ... anti-cancer properties. , The research was co-led ... used samples of human breast cancer cells to induce ...
(Date:7/13/2014)... release is available in French . ... An international research project, led by the Research ... Montreal, reports that a new oral medication is showing ... congenital amaurosis (LCA). Until now, this inherited retinal disease ... complete blindness, has remained untreatable. The study is published ...
(Date:7/11/2014)... eastern New South Wales, Australia when NASA,s Aqua satellite ... on July 11 (12:35 p.m. local time/11:35 p.m. EDT ... South Wales (NSW), the Moderate Resolution Imaging Spectroradiometer (MODIS) ... and spotted smoke (light brown) from various fires. Actively ... in red. , The New South Wales, Australia Government ...
Breaking Biology News(10 mins):UEA research reveals how cannabis compound could slow tumour growth 2MUHC researcher unveils novel treatment for a form of childhood blindness 2
... of California, San Francisco (UCSF) have uncovered a handful ... offering a new tool for understanding obesity and finding ... described in a paper published this month in the ... took armies of microscopic worms called C.elegans ...
... multitouch microscope integrates two Finnish innovations and brings new ... Institute for Molecular Medicine Finland (FIMM) have in collaboration ... and finger gesture controlled microscope. The method is a ... giant-size multitouch display. The result is an entirely ...
... NEW YORK, March 24, 2011 Reportlinker.com announces ... in its catalogue: Bioinformatics ... http://www.reportlinker.com/p0461692/Bioinformatics-–-A-Global-Market-Overview.html At the ... in creating and maintaining a database that stored ...
Cached Biology News:UCSF team shows how to make skinny worms fat and fat worms skinny 2UCSF team shows how to make skinny worms fat and fat worms skinny 3Big size multitouch display turned into a microscope 2Reportlinker Adds Bioinformatics - A Global Market Overview 2Reportlinker Adds Bioinformatics - A Global Market Overview 3Reportlinker Adds Bioinformatics - A Global Market Overview 4Reportlinker Adds Bioinformatics - A Global Market Overview 5Reportlinker Adds Bioinformatics - A Global Market Overview 6Reportlinker Adds Bioinformatics - A Global Market Overview 7Reportlinker Adds Bioinformatics - A Global Market Overview 8Reportlinker Adds Bioinformatics - A Global Market Overview 9Reportlinker Adds Bioinformatics - A Global Market Overview 10Reportlinker Adds Bioinformatics - A Global Market Overview 11Reportlinker Adds Bioinformatics - A Global Market Overview 12Reportlinker Adds Bioinformatics - A Global Market Overview 13Reportlinker Adds Bioinformatics - A Global Market Overview 14Reportlinker Adds Bioinformatics - A Global Market Overview 15Reportlinker Adds Bioinformatics - A Global Market Overview 16Reportlinker Adds Bioinformatics - A Global Market Overview 17Reportlinker Adds Bioinformatics - A Global Market Overview 18Reportlinker Adds Bioinformatics - A Global Market Overview 19Reportlinker Adds Bioinformatics - A Global Market Overview 20
... spectrofluorometer with a minimum 1 nm resolution ... or greater for the Raman band of ... keep in mind in order to meet ... or anisotropic measurements. ,The FP-6500 is designed ...
... Microarrays designed for genome-wide microRNA expression ... and powerful Paraflo microfluidic on-chip synthesis ... part of our comprehensive microRNA Expression ... The Arabidopsis microRNA Microarray contains ...
... Microarrays designed for genome-wide microRNA expression ... powerful Paraflo microfluidic on-chip synthesis platform. These ... comprehensive microRNA Expression Profiling Service. ... contains all known cow microRNAs (108 unique ...
... microRNA expression profiling and built on ... on-chip synthesis platform. These microarrays are ... microRNA Expression Profiling Service. ... Microarray contains all known virus microRNAs ...
Biology Products: