Navigation Links
SGX Pharmaceuticals Announces First Quarter Financial Results and Gives Pipeline Update
Date:5/13/2008

development of SGX523.

SGX126: The Company is continuing development of SGX126. While SGX126 shares many of the attractive preclinical properties of SGX523, it is structurally distinct, more potent in vivo and, based on the results of preclinical studies, has a different metabolism profile than that of SGX523. The Company intends to carry out further preclinical studies on SGX126 in support of clinical development and an IND submission is now targeted for early 2009.

Additional MET Inhibitors: In addition to SGX126, the Company has a number of MET inhibitors with attractive potency, selectivity and pharmacokinetic properties that it is evaluating as further MET development candidates.

BCR-ABL Program

SGX393: The Company's internal BCR-ABL program, focused on relapsed and refractory CML patients, in particular those with the T315I mutation, is progressing through IND-enabling studies, with an IND submission targeted for this quarter. Novartis continues to be responsible for the further preclinical and clinical development of BCR-ABL inhibitors identified under the collaboration, other than SGX393.

Oncology Drug Discovery

In addition to the JAK2 and RAS programs described previously, the Company's drug discovery portfolio includes other exciting cancer targets, such as RON, ALK, and IKKe. The JAK2, RON, and ALK programs are the more advanced drug discovery programs and the Company is targeting nomination of at least two development candidates from its drug discovery portfolio later this year.

Financial Results for the Three Months Ended March 31, 2008

Total revenues in the first quarter of 2008 were $17.0 million compared to $11.0 million in the first quarter of 2007. The increase of $6.0 million is primarily due to an increase in revenue recognized under the Novartis collaboration. Specifically, upon the conclusion of the research term of the collaboration in late March 2008, the Company recognized as revenue ap
'/>"/>

SOURCE SGX Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6 7 8

Related biology technology :

1. Vion Pharmaceuticals Pays Interest on 7.75% Convertible Senior Notes
2. China Biopharmaceuticals Holdings Announces Second Quarter 2007 Financial Results
3. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
4. XTL Biopharmaceuticals Announces Financial Results for the Six Months Ended June 30, 2007
5. Cadence Pharmaceuticals Reports Second Quarter 2007 Financial Results
6. Nabi Biopharmaceuticals to Present at Upcoming Industry Conferences
7. Anadys Pharmaceuticals Appoints Steve Worland, Ph.D. as President and Chief Executive Officer
8. Poniard Pharmaceuticals Announces Participation in Upcoming Conferences
9. NovaQuest Advances Virtual Development Model With Strategic Investment in TOPIGEN Pharmaceuticals
10. Drug Royalty Corporation (DRC) Announces Acquisition Regarding PEG-INTRON(R) From Enzon Pharmaceuticals, Inc. (ENZN)
11. Sunesis Pharmaceuticals Announces Reorganization to Focus Resources and Build Value in Clinical-Stage Programs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2008)...rstCall/ -- InterMune, Inc.,(Nasdaq: ITMN ) annou...8,financial results and provide a business update ...me. A live conference call and webcast will be,hos...me day., To access the live teleconference, dial ...), conference ID# 57393097. To access the,webcast,...
(Date:7/24/2008)...Help Spearhead Growth, PITTSBURGH, July 24 /PRNew.../www.hmsinc.com ), pioneering health informatics s...been appointed vice president, sales., Dockrell b...ales,management and product distribution for a ran...armaceutical companies., "Karen has an impressive...
(Date:7/24/2008)...tCall/ -- Hologic, Inc.,(Nasdaq: HOLX ) today ann...er by its direct wholly-owned subsidiary, Thunder ...ve Technologies, Inc. (Nasdaq: TWTI ) at a,price ...ring period expired at 12:00 midnight, New York Ci...tender offer period expired,at 12:00 midnight, New...
(Date:7/24/2008)...tant Advance in Radiofrequency ...uly 24 /- PEAK Surgical, Inc., a,medi... dissection system,based on a proprietary technolo...ministration has granted the company 510(k) cleara...n general surgery. The PEAK Surgery System,combine...
Breaking Biology Technology:InterMune to Release Second Quarter 2008 Financial Results and Provide Business Update on July 31 2Health Monitoring Systems Appoints Karen S. Dockrell As VP, Sales 2Hologic Completes Cash Tender Offer for Third Wave Technologies, Inc. 2Hologic Completes Cash Tender Offer for Third Wave Technologies, Inc. 3Hologic Completes Cash Tender Offer for Third Wave Technologies, Inc. 4PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 2PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 3PEAK Surgical Receives 510(k) Clearance to Market PEAK(R) Surgery System for Use in General Surgery 4
..., Achieving Ultra Fast Liquid Chromatograph...een designed to achieve,Ultra-Fast HPLC by utili...pect, we are successful,in demonstrating high sp... to high pressure, while providing high,reliabil...t,LC systems., Smaller particle columns ...
...T.J. Higley and Roy Eksteen, Tosoh Bioscience LLC,... Lexigen Pharmaceuticals, Lexington, Massachusetts...uring method development, many variables are exami...s such as elution profile, peak shape, and recover...GLP protocols. During a recent method , r...
..., Introduction , It is well k...icles are , more efficient at the expense... packed with larger particles. The gain in ef...ing column length, which in turn results in shorte...pressure. , Recently, two lines of 5 micro...
... Key words: Amino Acids, RP-HPLC, Precolumn deri...pionic acid, Ultraviolet detection., , ...cids do not significantly absorb light in the UV/..., their analysis normally includes a derivatisati...cursor to yield a strong UV/Visible chromophore or...
Other Biology Technology:Prominence UFLC 2Prominence UFLC 3Prominence UFLC 4Prominence UFLC 5Prominence UFLC 6Prominence UFLC 7Prominence UFLC 8Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column 2Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column 3Three Micron TSK-GEL ODS-100V Columns for High Throughput LCMS 2ANALYSIS OF AMINO ACIDS BY REVERSED PHASE CHROMATOGRAPHY WITH PRECOLUMN DERIVATISATION AND UV/VISIBLE DETECTION 2ANALYSIS OF AMINO ACIDS BY REVERSED PHASE CHROMATOGRAPHY WITH PRECOLUMN DERIVATISATION AND UV/VISIBLE DETECTION 3
(Date:7/23/2008)...y 24, 2008 One of the reasons people on low-carbo...their intake of fructose, a type of sugar that can...earcher at UT Southwestern Medical Center. , D...l nutrition and lead author of a study appearing i...aid her team,s findings suggest that the right typ...
(Date:7/23/2008)... parasites living in three estuaries on the Pacifi...hers have determined that biomass of these parasit... more than 20 times. , Their findings, which cou...ications, appear in this week,s issue of the journ...atter that exists in a given habitat. It is expres...
(Date:7/23/2008)... recent study shows that popular fish oil suppleme..., acute wounds in human skin. But whether that eff...cted, remains a mystery. , The omega-3 fatty aci...efit cardiovascular health and other diseases rela...inflammatory properties. But insufficient inflamma...
(Date:7/23/2008)...alif.) - In a study of free-living and parasitic s...California and Baja California, a team of research...ra, the United States Geological Survey, and Princ...ss in those habitats exceeds that of top predators... which could have significant biomedical and ecolo...
Breaking Biology News(10 mins):Limiting fructose may boost weight loss, UT Southwestern researcher reports 2Limiting fructose may boost weight loss, UT Southwestern researcher reports 3Parasites outweigh predators in Pacific Coast estuaries 2Parasites outweigh predators in Pacific Coast estuaries 3Scientists suspect omega-3 fatty acids could slow acute wound healing 2Scientists suspect omega-3 fatty acids could slow acute wound healing 3Scientists suspect omega-3 fatty acids could slow acute wound healing 4Study shows parasites outweigh predators 2Study shows parasites outweigh predators 3Results of TRIUMPH 1 Trial of Viveta in Pulmonary Arterial Hypertension to Be Announced Before Market Open on Thursday November 1 2007 711 1Results of TRIUMPH 1 Trial of Viveta in Pulmonary Arterial Hypertension to Be Announced Before Market Open on Thursday November 1 2007 711 2Health Insurance Agents Warn Against Imposing a Health Care Reform Tax in California 5163 1Health Insurance Agents Warn Against Imposing a Health Care Reform Tax in California 5163 2Health Insurance Agents Warn Against Imposing a Health Care Reform Tax in California 5163 3Boston Scientific Announces Verdict in Cordis Litigation 5159 1Boston Scientific Announces Verdict in Cordis Litigation 5159 2Boston Scientific Announces Verdict in Cordis Litigation 5159 3Diverse Partners Renew Commitment to Reproductive Health Rights in Asia 5155 1Diverse Partners Renew Commitment to Reproductive Health Rights in Asia 5155 2Diverse Partners Renew Commitment to Reproductive Health Rights in Asia 5155 3
...ng and action originates from the electrical signa...ngle of circuits. At this fundamental level, scien...y have lacked tools to understand what,s going wro... Parkinson,s disease. New Stanford-led research pu... technique to directly control brain cell activity...
...n humans, scientists have found early indicators o...elated injuries caused by repetitive motion. , Th... and prevention of debilitating conditions such as...ew study from Temple University senior researchers...t, Stephen Carp, in the March issue of Clinical Sc...
...he Ludwig Institute for Cancer Research (LICR) and...hool of Medicine have made a breakthrough in ident...cording to a report published online today in Natu...y genes (the ,what,) within the genome, it cannot ...hen, and ,where, gene products are expressed. Howe...
...s thought to be caused by hypoglycemic coma actual...e coma, according to a study in rodents led by res..., The results are surprising, say the authors, and... of diabetics in hypoglycemic coma, though they ca...polated to humans. , Insulin is an essential ho...
Other Biology News:A 'traffic light' for neurons means 'go' for improving brain research 2A 'traffic light' for neurons means 'go' for improving brain research 3A 'traffic light' for neurons means 'go' for improving brain research 4Red flag for repetitive stress injuries identified for first time in humans 2Beyond the DNA: Chemical signatures reveal genetic switches in the genome 2Glucose triggers brain cell death in rats after hypoglycemic coma 2Glucose triggers brain cell death in rats after hypoglycemic coma 3